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We evaluate the performance of federated learning (FL) in developing deep learning models for analysis of digitized tissue sections. A classification application was considered as the example use case, on quantifiying the distribution of…
Modern single-cell flow and mass cytometry technologies measure the expression of several proteins of the individual cells within a blood or tissue sample. Each profiled biological sample is thus represented by a set of hundreds of…
Advances in sensor technology and automation have ushered in an era of data abundance, where the ability to identify and extract relevant information in real time has become increasingly critical. Traditional filtering approaches, which…
Despite recent advancements in deep learning, deep neural networks continue to suffer from performance degradation when applied to new data that differs from training data. Test-time adaptation (TTA) aims to address this challenge by…
As the quantities of data recorded by embedded edge sensors grow, so too does the need for intelligent local processing. Such data often comes in the form of time-series signals, based on which real-time predictions can be made locally…
In this paper, we present contemporary techniques for visualising the feature space of a deep learning image classification neural network. These techniques are viewed in the context of a feed-forward network trained to classify low…
Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…
The process of identifying and characterizing B-cell epitopes, which are the portions of antigens recognized by antibodies, is important for our understanding of the immune system, and for many applications including vaccine development,…
Accurate annotation of fixation type is a critical step in slide preparation for pathology laboratories. However, this manual process is prone to errors, impacting downstream analyses and diagnostic accuracy. Existing methods for verifying…
Under the impact of global climate changes and human activities, harmful algae blooms in surface waters have become a growing concern due to negative impacts on water related industries. Therefore, reliable and cost effective methods of…
The discovery of patterns associated with diagnosis, prognosis, and therapy response in digital pathology images often requires intractable labeling of large quantities of histological objects. Here we release an open-source labeling tool,…
Sclera segmentation is crucial for developing automatic eye-related medical computer-aided diagnostic systems, as well as for personal identification and verification, because the sclera contains distinct personal features. Deep…
Bright-field microscopy, a cost-effective solution for live-cell culture, is often the only resource available, along with standard CPUs, for many low-budget labs. The inherent challenges of bright-field images -- their noisiness, low…
Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and…
Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…
A major challenge that prevents the training of DL models is the limited availability of accurately labeled data. This shortcoming is highlighted in areas where data annotation becomes a time-consuming and error-prone task. In this regard,…
Federated Learning(FL) is a privacy-preserving machine learning paradigm where a global model is trained in-situ across a large number of distributed edge devices. These systems are often comprised of millions of user devices and only a…
Monitoring cavity-nesting wild bees and wasps is vital for biodiversity research and conservation. Layer trap nests (LTNs) are emerging as a valuable tool to study the abundance and species richness of these insects, offering insights into…
High-throughput screening using automated microscopes is a key driver in biopharma drug discovery, enabling the parallel evaluation of thousands of drug candidates for diseases such as cancer. Traditional image analysis and deep learning…
High-quality labeled datasets are essential for deep learning. Traditional manual annotation methods are not only costly and inefficient but also pose challenges in specialized domains where expert knowledge is needed. Self-supervised…