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Digital assays represent a shift from traditional diagnostics and enable the precise detection of low-abundance analytes, critical for early disease diagnosis and personalized medicine, through discrete counting of biomolecular reporters.…

Computational Physics · Physics 2025-12-08 Neil H. Kim , Xiao-Liu Chu , Joseph B. DeGrandchamp , Matthew R. Foreman

Accurate annotation of fixation type is a critical step in slide preparation for pathology laboratories. However, this manual process is prone to errors, impacting downstream analyses and diagnostic accuracy. Existing methods for verifying…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Oskar Thaeter , Tanja Niedermair , Jan E. G. Albin , Johannes Raffler , Ralf Huss , Peter J. Schüffler

Segmentation is one of the most important tasks in the medical imaging pipeline as it influences a number of image-based decisions. To be effective, fully supervised segmentation approaches require large amounts of manually annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Tyler Ward , Aaron Moseley , Abdullah-Al-Zubaer Imran

Automatically determining the position of every slice in a CT scan is a basic yet powerful capability allowing fast retrieval of region of interest for visual inspection and automated analysis. Unlike conventional localization approaches…

Image and Video Processing · Electrical Eng. & Systems 2023-12-06 Amit Oved

[Purpose] The pathology is decisive for disease diagnosis, but relies heavily on the experienced pathologists. Recently, pathological artificial intelligence (PAI) is thought to improve diagnostic accuracy and efficiency. However, the high…

Image and Video Processing · Electrical Eng. & Systems 2022-05-25 Yuanqing Yang , Kai Sun , Yanhua Gao , Kuangsong Wang , Gang Yu

In digital pathology, acquiring all-in-focus images is essential to high-quality imaging and high-efficient clinical workflow. Traditional scanners achieve this by scanning at multiple focal planes of varying depths and then merging them,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Jiangdong Cai , Yan Chen , Zhenrong Shen , Haotian Jiang , Honglin Xiong , Kai Xuan , Lichi Zhang , Qian Wang

Pathology images of histopathology can be acquired from camera-mounted microscopes or whole slide scanners. Utilizing similarity calculations to match patients based on these images holds significant potential in research and clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-03-25 H. R. Tizhoosh , Liron Pantanowitz

With the rapid growth of the PCB manufacturing industry, there is an increasing demand for computer vision inspection to detect defects during production. Improving the accuracy and generalization of PCB defect detection models remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Bowen Liu , Dongjie Chen , Xiao Qi

Objective: Surveillance imaging of chronic aortic diseases, such as dissections, relies on obtaining and comparing cross-sectional diameter measurements at predefined aortic landmarks, over time. Due to a lack of robust tools, the…

Cervical spondylosis, a complex and prevalent condition, demands precise and efficient diagnostic techniques for accurate assessment. While MRI offers detailed visualization of cervical spine anatomy, manual interpretation remains…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Qi Zhang , Xiuyuan Chen , Ziyi He , Lianming Wu , Kun Wang , Jianqi Sun , Hongxing Shen

Deep learning classifiers for characterization of whole slide tissue morphology require large volumes of annotated data to learn variations across different tissue and cancer types. As is well known, manual generation of digital pathology…

Image and Video Processing · Electrical Eng. & Systems 2019-07-10 Shahira Abousamra , Le Hou , Rajarsi Gupta , Chao Chen , Dimitris Samaras , Tahsin Kurc , Rebecca Batiste , Tianhao Zhao , Shroyer Kenneth , Joel Saltz

Computer vision has transformed medical diagnosis, treatment, and research through advanced image processing and machine learning techniques. Fracture classification, a critical area in healthcare, has greatly benefited from these…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Snigdha Paul , Sambit Mallick , Anindya Sen

Mammography is a vital screening technique for early revealing and identification of breast cancer in order to assist to decrease mortality rate. Practical applications of mammograms are not limited to breast cancer revealing,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-08 Aparna Bhale , Manish Joshi

Efforts to utilize growing volumes of clinical imaging data to generate tumor evaluations continue to require significant manual data wrangling owing to the data heterogeneity. Here, we propose an artificial intelligence-based solution for…

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Algorithmic decision support is rapidly becoming a staple of personalized medicine, especially for high-stakes recommendations in which access to certain information can drastically alter the course of treatment, and thus, patient outcome;…

Computer Vision and Pattern Recognition · Computer Science 2021-08-16 Haomin Chen , T. Y. Alvin Liu , Catalina Gomez , Zelia Correa , Mathias Unberath

Automatic cell image segmentation methods in connectomics produce merge and split errors, which require correction through proofreading. Previous research has identified the visual search for these errors as the bottleneck in interactive…

Computer Vision and Pattern Recognition · Computer Science 2017-04-05 Daniel Haehn , Verena Kaynig , James Tompkin , Jeff W. Lichtman , Hanspeter Pfister

An accurate steatosis quantification with pathology tissue samples is of high clinical importance. However, such pathology measurement is manually made in most clinical practices, subject to severe reader variability due to large sampling…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Mousumi Roy , Fusheng Wang , George Teodoro , Miriam B Vos , Alton Brad Farris , Jun Kong

Ensuring the structural integrity and safety of bridges is crucial for the reliability of transportation networks and public safety. Traditional crack detection methods are increasingly being supplemented or replaced by advanced artificial…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Woubishet Zewdu Taffese , Ritesh Sharma , Mohammad Hossein Afsharmovahed , Gunasekaran Manogaran , Genda Chen

Recent advances in agentic artificial intelligence, i.e. systems capable of autonomous perception, reasoning, and tool use, offer new opportunities for digital pathology. In this pilot study, we evaluate whether two agentic multimodal AI…

Human-Computer Interaction · Computer Science 2026-01-21 Marc Aubreville , Taryn A. Donovan , Christof A. Bertram
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