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Machine learning models for medical image analysis often suffer from poor performance on important subsets of a population that are not identified during training or testing. For example, overall performance of a cancer detection model may…

Machine Learning · Computer Science 2019-11-18 Luke Oakden-Rayner , Jared Dunnmon , Gustavo Carneiro , Christopher Ré

Machine learning (ML) models are increasingly used to support clinical decision-making. However, real-world medical datasets are often noisy, incomplete, and imbalanced, leading to performance disparities across patient subgroups. These…

Analyzing machine learning model performance stratified by patient and recording properties is becoming the accepted norm and often yields crucial insights about important model failure modes. Performing such analyses in a statistically…

Machine Learning · Computer Science 2025-12-22 Dishantkumar Sutariya , Eike Petersen

Machine learning models have achieved high overall accuracy in medical image analysis. However, performance disparities on specific patient groups pose challenges to their clinical utility, safety, and fairness. This can affect known…

Machine Learning · Computer Science 2024-10-23 Vincent Olesen , Nina Weng , Aasa Feragen , Eike Petersen

In machine learning, disparity metrics are often defined by measuring the difference in the performance or outcome of a model, across different sub-populations (groups) of datapoints. Thus, the inputs to disparity quantification consist of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-15 Shervin Ardeshir , Cristina Segalin , Nathan Kallus

Distribution shifts remain a fundamental problem for the safe application of machine learning systems. If undetected, they may impact the real-world performance of such systems or will at least render original performance claims invalid. In…

Machine Learning · Computer Science 2023-03-10 Lisa M. Koch , Christian M. Schürch , Christian F. Baumgartner , Arthur Gretton , Philipp Berens

We investigate performance disparities in deep classifiers. We find that the ability of classifiers to separate individuals into subgroups varies substantially across medical imaging modalities and protected characteristics; crucially, we…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Charles Jones , Mélanie Roschewitz , Ben Glocker

Across a wide array of disciplines, many researchers use machine learning (ML) algorithms to identify a subgroup of individuals who are likely to benefit from a treatment the most (``exceptional responders'') or those who are harmed by it.…

Methodology · Statistics 2025-09-03 Michael Lingzhi Li , Kosuke Imai

Machine learning (ML) models that achieve high average accuracy can still underperform on semantically coherent subsets ("slices") of data. This behavior can have significant societal consequences for the safety or bias of the model in…

Human-Computer Interaction · Computer Science 2024-02-12 Nari Johnson , Ángel Alexander Cabrera , Gregory Plumb , Ameet Talwalkar

Machine learning (ML) is increasingly employed in real-world applications like medicine or economics, thus, potentially affecting large populations. However, ML models often do not perform homogeneously, leading to underperformance or,…

Machine Learning · Computer Science 2025-08-28 Tom Siegl , Kutalmış Coşkun , Bjarne C. Hiller , Amin Mirzaei , Florian Lemmerich , Martin Becker

Supervised learning models often make systematic errors on rare subsets of the data. When these subsets correspond to explicit labels in the data (e.g., gender, race) such poor performance can be identified straightforwardly. This paper…

Machine Learning · Computer Science 2021-10-19 Greg d'Eon , Jason d'Eon , James R. Wright , Kevin Leyton-Brown

Machine learning (ML) algorithms can often differ in performance across domains. Understanding $\textit{why}$ their performance differs is crucial for determining what types of interventions (e.g., algorithmic or operational) are most…

Machine Learning · Computer Science 2024-02-23 Jean Feng , Harvineet Singh , Fan Xia , Adarsh Subbaswamy , Alexej Gossmann

It has been rightfully emphasized that the use of AI for clinical decision making could amplify health disparities. An algorithm may encode protected characteristics, and then use this information for making predictions due to undesirable…

Machine Learning · Computer Science 2022-07-22 Ben Glocker , Charles Jones , Melanie Bernhardt , Stefan Winzeck

Machine learning in medicine leverages the wealth of healthcare data to extract knowledge, facilitate clinical decision-making, and ultimately improve care delivery. However, ML models trained on datasets that lack demographic diversity…

Machine Learning · Computer Science 2021-11-19 Songzi Liu , Yuan Luo

As in traditional machine learning models, models trained with federated learning may exhibit disparate performance across demographic groups. Model holders must identify these disparities to mitigate undue harm to the groups. However,…

Machine Learning · Computer Science 2023-01-12 Marc Juarez , Aleksandra Korolova

Machine learning (ML) models frequently experience performance degradation when deployed in new contexts. Such degradation is rarely uniform: some subgroups may suffer large performance decay while others may not. Understanding where and…

Machine Learning · Computer Science 2025-06-03 Harvineet Singh , Fan Xia , Alexej Gossmann , Andrew Chuang , Julian C. Hong , Jean Feng

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

We study the problem of understanding where two populations differ within a feature space, which we formalize in the concept of a differential subgroup: a subset of individuals from both populations who, despite sharing similar…

Machine Learning · Computer Science 2026-05-01 Sascha Xu , Jilles Vreeken

Classifiers in machine learning are often brittle when deployed. Particularly concerning are models with inconsistent performance on specific subgroups of a class, e.g., exhibiting disparities in skin cancer classification in the presence…

Machine Learning · Computer Science 2020-08-18 Karan Goel , Albert Gu , Yixuan Li , Christopher Ré

Monitoring machine learning systems post deployment is critical to ensure the reliability of the systems. Particularly importance is the problem of monitoring the performance of machine learning systems across all the data subgroups…

Machine Learning · Computer Science 2022-12-19 Huong Ha
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