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AI-based vascular segmentation is becoming increasingly common in enhancing the screening and treatment of ophthalmic diseases. Deep learning structures based on U-Net have achieved relatively good performance in vascular segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Zhihao Zhao , Yinzheng Zhao , Junjie Yang , Kai Huang , Nassir Navab , M. Ali Nasseri

Liver cirrhosis is a major global health problem causing millions of deaths annually, and timely detection with aggressive treatment can significantly improve patients' quality of life. Modelling complex diseases from biomedical data is…

Other Quantitative Biology · Quantitative Biology 2026-04-29 Xueyuan Huang , Yuheng Wang , Yuanzhi He , Siqi Gou , Lu Bai , Wenqian Wu , Peifeng Liu , Aijia Wang , Tianhui Fan , Ze Zhou , Jiayu Xu

In this paper, we propose a method for characterizing 3D shapes from point clouds and we show a direct application on a study of organ temporal deformations. As an example, we characterize the behavior of a bladder during a forced…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Karim Makki , Amine Bohi , Augustin C. Ogier , Marc-Emmanuel Bellemare

We propose a new framework that formulates point cloud registration as a denoising diffusion process from noisy transformation to object transformation. During training stage, object transformation diffuses from ground-truth transformation…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Yue Wu , Yongzhe Yuan , Xiaolong Fan , Xiaoshui Huang , Maoguo Gong , Qiguang Miao

Abdominal CT data are limited by high annotation costs and privacy constraints, which hinder the development of robust segmentation and diagnostic models. We present a Prior-Integrated Variation Modeling (PIVM) framework, a diffusion-based…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Dinglun He , Baoming Zhang , Xu Wang , Yao Hao , Deshan Yang , Ye Duan

As the demand for more descriptive machine learning models grows within medical imaging, bottlenecks due to data paucity will exacerbate. Thus, collecting enough large-scale data will require automated tools to harvest data/label pairs from…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Bo Zhou , Adam P. Harrison , Jiawen Yao , Chi-Tung Cheng , Jing Xiao , Chien-Hung Liao , Le Lu

Accurate segmentation of the liver is a prerequisite for the diagnosis of disease. Automated segmentation is an important application of computer-aided detection and diagnosis of liver disease. In recent years, automated processing of…

Image and Video Processing · Electrical Eng. & Systems 2022-06-29 Zhiqi Lee , Sumin Qi , Chongchong Fan , Ziwei Xie

This work introduces a new latent diffusion model to generate high-quality 3D chest CT scans conditioned on 3D anatomical masks. The method synthesizes volumetric images of size 256x256x256 at 1 mm isotropic resolution using a single…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anna Oliveras , Roger Marí , Rafael Redondo , Oriol Guardià , Ana Tost , Bhalaji Nagarajan , Carolina Migliorelli , Vicent Ribas , Petia Radeva

Precise segmentation of organs and tumors plays a crucial role in clinical applications. It is a challenging task due to the irregular shapes and various sizes of organs and tumors as well as the significant class imbalance between the…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Ziqiang Li , Hong Pan , Yaping Zhu , A. K. Qin

Expansion of diffusion MRI (dMRI) both into the realm of strong gradients, and into accessible imaging with portable low-field devices, brings about the challenge of gradient nonlinearities. Spatial variations of the diffusion gradients…

Computed tomography (CT) is one of the modalities for effective lung cancer screening, diagnosis, treatment, and prognosis. The features extracted from CT images are now used to quantify spatial and temporal variations in tumors. However,…

Image and Video Processing · Electrical Eng. & Systems 2023-03-28 Md Selim , Jie Zhang , Michael A. Brooks , Ge Wang , Jin Chen

Denoising diffusion models hold great promise for generating diverse and realistic human motions. However, existing motion diffusion models largely disregard the laws of physics in the diffusion process and often generate…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Ye Yuan , Jiaming Song , Umar Iqbal , Arash Vahdat , Jan Kautz

Diffusion-weighted (DW) MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells. Recent developments in micro-structure imaging and…

Background: The assessment of left ventricular (LV) function by myocardial perfusion SPECT (MPS) relies on accurate myocardial segmentation. The purpose of this paper is to develop and validate a new method incorporating deep learning with…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Fubao Zhu , Jinyu Zhao , Chen Zhao , Shaojie Tang , Jiaofen Nan , Yanting Li , Zhongqiang Zhao , Jianzhou Shi , Zenghong Chen , Zhixin Jiang , Weihua Zhou

Precise and automated segmentation of the liver and its tumor within CT scans plays a pivotal role in swift diagnosis and the development of optimal treatment plans for individuals with liver diseases and malignancies. However, automated…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Chandravardhan Singh Raghaw , Jasmer Singh Sanjotra , Mohammad Zia Ur Rehman , Shubhi Bansal , Shahid Shafi Dar , Nagendra Kumar

Modeling of respiratory motion is important for a more accurate understanding and accounting of its effect on dose to cancers in the thorax and abdomen by radiotherapy. We have developed a model of respiration-induced organ motion in the…

Optical microscopy is an essential tool in biology and medicine. Imaging thin, yet non-flat objects in a single shot (without relying on more sophisticated sectioning setups) remains challenging as the shallow depth of field that comes with…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Adrian Shajkofci , Michael Liebling

Medical image segmentation is critical for diagnosing and treating spinal disorders. However, the presence of high noise, ambiguity, and uncertainty makes this task highly challenging. Factors such as unclear anatomical boundaries,…

Image and Video Processing · Electrical Eng. & Systems 2023-09-13 Zhiqing Zhang , Guojia Fan , Tianyong Liu , Nan Li , Yuyang Liu , Ziyu Liu , Canwei Dong , Shoujun Zhou

The point spread function (PSF) is fundamental to any type of microscopy, most importantly so for single-molecule localization techniques, where the exact PSF shape is crucial for precise molecule localization at the nanoscale. However,…

In the field of 3D medical imaging, accurately extracting and representing the blood vessels with curvilinear structures holds paramount importance for clinical diagnosis. Previous methods have commonly relied on discrete representation…

Computer Vision and Pattern Recognition · Computer Science 2025-06-09 Ziwei Zhao , Zhixing Zhang , Yuhang Liu , Zhao Zhang , Haojun Yu , Dong Wang , Liwei Wang