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Generative Pre-trained Transformer (GPT) models have achieved remarkable performance on various natural language processing tasks, and have shown great potential as backbones for audio-and-text large language models (LLMs). Previous…

Classes, as fundamental elements of Computer Vision, have been extensively studied within incremental learning frameworks. In contrast, tokens, which play essential roles in many research fields, exhibit similar characteristics of growth,…

Machine Learning · Computer Science 2025-11-19 Jiaxin Qi , Yan Cui , Jianqiang Huang , Gaogang Xie

Single-cell RNA sequencing (scRNA-seq) provides a high throughput, quantitative and unbiased framework for scientists in many research fields to identify and characterize cell types within heterogeneous cell populations from various…

Quantitative Methods · Quantitative Biology 2022-09-28 Yeganeh Madadi , Aboozar Monavarfeshani , Hao Chen , W. Daniel Stamer , Robert W. Williams , Siamak Yousefi

The emerging paradigm of leveraging pretrained large language models (LLMs) for time series forecasting has predominantly employed linguistic-temporal modality alignment strategies through token-level or layer-wise feature mapping. However,…

Artificial Intelligence · Computer Science 2025-05-20 Siming Sun , Kai Zhang , Xuejun Jiang , Wenchao Meng , Qinmin Yang

This paper investigates how Large Language Models (LLMs) represent non-English tokens -- a question that remains underexplored despite recent progress. We propose a lightweight intervention method using representation steering, where a…

Computation and Language · Computer Science 2025-08-27 Omar Mahmoud , Buddhika Laknath Semage , Thommen George Karimpanal , Santu Rana

Single-cell RNA sequencing (scRNA-seq) enables dissecting cellular heterogeneity in tissues, resulting in numerous biological discoveries. Various computational methods have been devised to delineate cell types by clustering scRNA-seq data…

Quantitative Methods · Quantitative Biology 2023-09-18 Tram Huynh , Zixuan Cang

RNAs are essential molecules that carry genetic information vital for life, with profound implications for drug development and biotechnology. Despite this importance, RNA research is often hindered by the vast literature available on the…

Genomics · Quantitative Biology 2024-11-15 Yijia Xiao , Edward Sun , Yiqiao Jin , Wei Wang

Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

We introduce Sentence-level Language Modeling, a new pre-training objective for learning a discourse language representation in a fully self-supervised manner. Recent pre-training methods in NLP focus on learning either bottom or top-level…

Computation and Language · Computer Science 2020-11-02 Haejun Lee , Drew A. Hudson , Kangwook Lee , Christopher D. Manning

Recent multimodal embedding approaches leveraging multimodal large language models (MLLMs) fine-tuned with contrastive learning (CL) have shown promising results, yet the underlying reasons behind their superiority remain underexplored.…

Computation and Language · Computer Science 2025-10-14 Chenghao Xiao , Hou Pong Chan , Hao Zhang , Weiwen Xu , Mahani Aljunied , Yu Rong

Scientific literature is growing exponentially, creating a critical bottleneck for researchers to efficiently synthesize knowledge. While general-purpose Large Language Models (LLMs) show potential in text processing, they often fail to…

Computation and Language · Computer Science 2025-09-11 Fengyu She , Nan Wang , Hongfei Wu , Ziyi Wan , Jingmian Wang , Chang Wang

The recent development of multimodal single-cell technology has made the possibility of acquiring multiple omics data from individual cells, thereby enabling a deeper understanding of cellular states and dynamics. Nevertheless, the…

Genomics · Quantitative Biology 2023-10-16 Wenzhuo Tang , Hongzhi Wen , Renming Liu , Jiayuan Ding , Wei Jin , Yuying Xie , Hui Liu , Jiliang Tang

Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

With hundreds of thousands of language models available on Huggingface today, efficiently evaluating and utilizing these models across various downstream, tasks has become increasingly critical. Many existing methods repeatedly learn…

Computation and Language · Computer Science 2024-10-18 Richard Zhuang , Tianhao Wu , Zhaojin Wen , Andrew Li , Jiantao Jiao , Kannan Ramchandran

Speech representation learning plays a vital role in speech processing. Among them, self-supervised learning (SSL) has become an important research direction. It has been shown that an SSL pretraining model can achieve excellent performance…

Audio and Speech Processing · Electrical Eng. & Systems 2021-10-20 Yi-Chen Chen , Shu-wen Yang , Cheng-Kuang Lee , Simon See , Hung-yi Lee

Self-supervised graph representation learning (SSGRL) is a representation learning paradigm used to reduce or avoid manual labeling. An essential part of SSGRL is graph data augmentation. Existing methods usually rely on heuristics commonly…

Machine Learning · Computer Science 2024-12-25 Ahmed E. Samy , Zekarias T. Kefatoa , Sarunas Girdzijauskasa

This paper presents a self-supervised learning framework, named MGF, for general-purpose speech representation learning. In the design of MGF, speech hierarchy is taken into consideration. Specifically, we propose to use generative learning…

Sound · Computer Science 2021-02-04 Yucheng Zhao , Dacheng Yin , Chong Luo , Zhiyuan Zhao , Chuanxin Tang , Wenjun Zeng , Zheng-Jun Zha

Despite recent advancements in speech emotion recognition (SER) models, state-of-the-art deep learning (DL) approaches face the challenge of the limited availability of annotated data. Large language models (LLMs) have revolutionised our…

Sound · Computer Science 2024-06-21 Siddique Latif , Muhammad Usama , Mohammad Ibrahim Malik , Björn W. Schuller

Currently, learning better unsupervised sentence representations is the pursuit of many natural language processing communities. Lots of approaches based on pre-trained language models (PLMs) and contrastive learning have achieved promising…

Computation and Language · Computer Science 2023-05-11 Nuo Chen , Linjun Shou , Ming Gong , Jian Pei , Bowen Cao , Jianhui Chang , Daxin Jiang , Jia Li

Large Language Models (LLMs) have demonstrated superior abilities in tasks such as chatting, reasoning, and question-answering. However, standard LLMs may ignore crucial paralinguistic information, such as sentiment, emotion, and speaking…

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