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In the era of fast-paced precision medicine, observational studies play a major role in properly evaluating new treatments in clinical practice. Yet, unobserved confounding can significantly compromise causal conclusions drawn from…

Machine Learning · Statistics 2026-03-20 Piersilvio De Bartolomeis , Javier Abad , Konstantin Donhauser , Fanny Yang

As causal ground truth is incredibly rare, causal discovery algorithms are commonly only evaluated on simulated data. This is concerning, given that simulations reflect preconceptions about generating processes regarding noise…

Owing to the cross-pollination between causal discovery and deep learning, non-statistical data (e.g., images, text, etc.) encounters significant conflicts in terms of properties and methods with traditional causal data. To unify these data…

Machine Learning · Computer Science 2023-08-14 Hang Chen , Xinyu Yang , Qing Yang

Entropic causal inference is a recent framework for learning the causal graph between two variables from observational data by finding the information-theoretically simplest structural explanation of the data, i.e., the model with smallest…

Machine Learning · Computer Science 2025-09-23 Spencer Compton , Kristjan Greenewald , Dmitriy Katz , Murat Kocaoglu

Causal disentanglement aims to learn about latent causal factors behind data, holding the promise to augment existing representation learning methods in terms of interpretability and extrapolation. Recent advances establish identifiability…

Machine Learning · Computer Science 2024-12-25 Ryan Welch , Jiaqi Zhang , Caroline Uhler

In the algorithm Intersort, Chevalley et al. (2024) proposed a score-based method to discover the causal order of variables in a Directed Acyclic Graph (DAG) model, leveraging interventional data to outperform existing methods. However, as…

Machine Learning · Computer Science 2024-10-14 Mathieu Chevalley , Arash Mehrjou , Patrick Schwab

Directed acyclic graphs (DAGs) constitute a central modeling tool to enable principled reasoning about cause-effect interactions in complex systems. However, since the causal structure underlying a group of variables is often unknown and…

Machine Learning · Statistics 2026-05-25 Gonzalo Mateos , Samuel Rey , Hamed Ajorlou , Mariano Tepper

If $X,Y,Z$ denote sets of random variables, two different data sources may contain samples from $P_{X,Y}$ and $P_{Y,Z}$, respectively. We argue that causal inference can help inferring properties of the 'unobserved joint distributions'…

Statistics Theory · Mathematics 2018-05-18 Dominik Janzing

While deep representation learning has become increasingly capable of separating task-relevant representations from other confounding factors in the data, two significant challenges remain. First, there is often an unknown and potentially…

Machine Learning · Computer Science 2019-05-07 Prashnna K Gyawali , Cameron Knight , Sandesh Ghimire , B. Milan Horacek , John L. Sapp , Linwei Wang

Assuming a directed acyclic graph (DAG) that represents prior knowledge of causal relationships between variables is a common starting point for cause-effect estimation. Existing literature typically invokes hypothetical domain expert…

Machine Learning · Statistics 2025-03-11 Kirtan Padh , Zhufeng Li , Cecilia Casolo , Niki Kilbertus

Open world object detection faces a significant challenge in domain-invariant representation, i.e., implicit non-causal factors. Most domain generalization (DG) methods based on domain adversarial learning (DAL) pay much attention to learn…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Zhilong Zhang , Lei Zhang , Qing He , Shuyin Xia , Guoyin Wang , Fuxiang Huang

Going beyond correlations, the understanding and identification of causal relationships in observational time series, an important subfield of Causal Discovery, poses a major challenge. The lack of access to a well-defined ground truth for…

Machine Learning · Statistics 2021-04-19 Andrew R. Lawrence , Marcus Kaiser , Rui Sampaio , Maksim Sipos

Causal discovery from observational data is a challenging task that can only be solved up to a set of equivalent solutions, called an equivalence class. Such classes, which are often large in size, encode uncertainties about the orientation…

Machine Learning · Computer Science 2022-03-01 Philippe Brouillard , Perouz Taslakian , Alexandre Lacoste , Sebastien Lachapelle , Alexandre Drouin

Graph data is becoming increasingly prevalent due to the growing demand for relational insights in AI across various domains. Organizations regularly use graph data to solve complex problems involving relationships and connections. Causal…

Machine Learning · Computer Science 2026-02-23 Simi Job , Xiaohui Tao , Taotao Cai , Haoran Xie , Jianming Yong , Xin Wang

We present a method for assessing the sensitivity of the true causal effect to unmeasured confounding. The method requires the analyst to set two intuitive parameters. Otherwise, the method is assumption-free. The method returns an interval…

Methodology · Statistics 2022-02-07 Jose M. Peña

A major challenge in estimating treatment effects in observational studies is the reliance on untestable conditions such as the assumption of no unmeasured confounding. In this work, we propose an algorithm that can falsify the assumption…

Methodology · Statistics 2025-06-03 Rickard K. A. Karlsson , Jesse H. Krijthe

Background: There is increasing interest in approaches for analyzing the effect of exposure mixtures on health. A key issue is how to simultaneously analyze often highly collinear components of the mixture, which can create problems such as…

Methodology · Statistics 2020-07-06 Thomas F. Webster , Marc G. Weisskopf

Understanding causal relationships among features is fundamental for explaining machine learning model decisions. However, traditional causal discovery methods face challenges with categorical variables due to numerical instability in…

Artificial Intelligence · Computer Science 2026-01-30 Henry Salgado , Meagan R. Kendall , Martine Ceberio

Unsupervised feature selection (UFS) has recently gained attention for its effectiveness in processing unlabeled high-dimensional data. However, existing methods overlook the intrinsic causal mechanisms within the data, resulting in the…

Machine Learning · Computer Science 2025-01-28 Zongxin Shen , Yanyong Huang , Dongjie Wang , Minbo Ma , Fengmao Lv , Tianrui Li

Nowadays, the need for causal discovery is ubiquitous. A better understanding of not just the stochastic dependencies between parts of a system, but also the actual cause-effect relations, is essential for all parts of science. Thus, the…

Machine Learning · Computer Science 2024-12-10 Boris Lorbeer , Mustafa Mohsen