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Banks utilize credit scoring as an important indicator of financial strength and eligibility for credit. Scoring models aim to assign statistical odds or probabilities for predicting if there is a risk of nonpayment in relation to many…

Risk Management · Quantitative Finance 2023-03-10 Oguz Koc , Omur Ugur , A. Sevtap Kestel

Background: Survival prediction models are often less reliable in clinical groups with limited sample sizes or few outcome events. Target-only models may be unstable, whereas models from larger cohorts may transfer poorly when risk-factor…

Methodology · Statistics 2026-05-18 Junhan Yu , Yurui Chen , Juan Delgado-SanMartin , Dennis Wang , Hong Pan , Doudou Zhou

Machine learning (ML) is poised to drive innovations in clinical microbiomics, such as in disease diagnostics and prognostics. However, the successful implementation of ML in these domains necessitates the development of reproducible,…

Genomics · Quantitative Biology 2024-12-02 Natasha K. Dudek , Mariam Chakhvadze , Saba Kobakhidze , Omar Kantidze , Yuriy Gankin

Blood biomarkers are an essential tool for healthcare providers to diagnose, monitor, and treat a wide range of medical conditions. Current reference values and recommended ranges often rely on population-level statistics, which may not…

Machine Learning · Computer Science 2024-07-11 A. Ali Heydari , Naghmeh Rezaei , Javier L. Prieto , Shwetak N. Patel , Ahmed A. Metwally

Optimal data detection in massive multiple-input multiple-output (MIMO) systems often requires prohibitively high computational complexity. A variety of detection algorithms have been proposed in the literature, offering different…

Econometrics · Economics 2025-07-02 Yong Li , Sushanta K. Mallick , Tao Zeng , Junxing Zhang

Probabilistic survival predictions from models trained with Maximum Likelihood Estimation (MLE) can have high, and sometimes unacceptably high variance. The field of meteorology, where the paradigm of maximizing sharpness subject to…

Machine Learning · Computer Science 2019-06-20 Anand Avati , Tony Duan , Sharon Zhou , Kenneth Jung , Nigam H. Shah , Andrew Ng

Creating impact in real-world settings requires artificial intelligence techniques to span the full pipeline from data, to predictive models, to decisions. These components are typically approached separately: a machine learning model is…

Machine Learning · Computer Science 2018-11-22 Bryan Wilder , Bistra Dilkina , Milind Tambe

Recent advances in probabilistic modelling have led to a large number of simulation-based inference algorithms which do not require numerical evaluation of likelihoods. However, a public benchmark with appropriate performance metrics for…

Machine Learning · Statistics 2021-04-12 Jan-Matthis Lueckmann , Jan Boelts , David S. Greenberg , Pedro J. Gonçalves , Jakob H. Macke

Model-based reinforcement learning (MBRL) is widely seen as having the potential to be significantly more sample efficient than model-free RL. However, research in model-based RL has not been very standardized. It is fairly common for…

In this paper, we present a technique for balancing predictive relevance models related to supervised modelling ligand biochemical activities to biological targets. We train uncalibrated models employing conventional supervised machine…

Machine Learning · Computer Science 2021-04-07 Marek Pecha

It is common to evaluate the performance of a machine learning model by measuring its predictive power on a test dataset. This approach favors complicated models that can smoothly fit complex functions and generalize well from training data…

Machine Learning · Computer Science 2022-10-07 Hugo Cisneros , Josef Sivic , Tomas Mikolov

Prognostic models in survival analysis are aimed at understanding the relationship between patients' covariates and the distribution of survival time. Traditionally, semi-parametric models, such as the Cox model, have been assumed. These…

Machine Learning · Statistics 2020-11-06 Denise Rava , Jelena Bradic

Variable selection problem for the nonlinear Cox regression model is considered. In survival analysis, one main objective is to identify the covariates that are associated with the risk of experiencing the event of interest. The Cox…

Machine Learning · Statistics 2022-11-18 Kexuan Li

Mixture cure models are widely used in survival analysis when a portion of patients is considered cured and is no longer at risk for the event of interest. In clinical settings, dynamic survival prediction is particularly important to…

Methodology · Statistics 2025-09-24 Marta Cipriani , Marco Alfò , Mirko Signorelli

Because large language models are expensive to pretrain on different datasets, using smaller-scale experiments to decide on data is crucial for reducing costs. Which benchmarks and methods of making decisions from observed performance at…

Pathology foundation models (PFMs) have recently emerged as powerful pretrained encoders for computational pathology, enabling transfer learning across a wide range of downstream tasks. However, systematic comparisons of these models for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Fredrik K. Gustafsson , Constance Boissin , Johan Vallon-Christersson , David A. Clifton , Mattias Rantalainen

This article analyzes the problem of estimating the time until an event occurs, also known as survival modeling. We observe through substantial experiments on large real-world datasets and use-cases that populations are largely…

Machine Learning · Computer Science 2019-05-13 David Hubbard , Benoit Rostykus , Yves Raimond , Tony Jebara

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

A significant level of stigma and inequality exists in mental healthcare, especially in under-served populations. Inequalities are reflected in the data collected for scientific purposes. When not properly accounted for, machine learning…

Longitudinal and time-to-event data are often analyzed in biomarker research to study the association between the longitudinal biomarker measurements and the event-time outcome, in which the longitudinal information contributes to the…

Methodology · Statistics 2025-09-09 Minzee Kim , Joel A. Dubin