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Magnetic Particle Imaging (MPI) is a tomographic imaging technique for determining the spatial distribution of superparamagnetic nanoparticles. Current MPI systems are capable of imaging iron masses over a wide dynamic range of more than…

Quantitative cardiac magnetic resonance imaging (MRI) is an increasingly important diagnostic tool for cardiovascular diseases. Yet, co-registration of all baseline images within the quantitative MRI sequence is essential for the accuracy…

Image and Video Processing · Electrical Eng. & Systems 2023-11-06 Xinqi Li , Yi Zhang , Yidong Zhao , Jan van Gemert , Qian Tao

Quantification of tissue parameters using MRI is emerging as a powerful tool in clinical diagnosis and research studies. The need for multiple long scans with different acquisition parameters prohibits quantitative MRI from reaching…

Quantitative Methods · Quantitative Biology 2024-08-07 Amir Heydari , Abbas Ahmadi , Tae Hyung Kim , Berkin Bilgic

Transcranial magnetic stimulation (TMS) is a popular method for the noninvasive stimulation of neurons in the brain. It has become a standard instrument in experimental brain research and is approved for a range of diagnostic and…

Medical Physics · Physics 2023-12-27 Max Koehler , Stefan Goetz

Ultra-high resolution 7 tesla (7T) magnetic resonance imaging (MRI) provides detailed anatomical views, offering better signal-to-noise ratio, resolution and tissue contrast than 3T MRI, though at the cost of accessibility. We present an…

Purpose: This study demonstrated an MR signal multitask learning method for 3D simultaneous segmentation and relaxometry of human brain tissues. Materials and Methods: A 3D inversion-prepared balanced steady-state free precession sequence…

Medical Physics · Physics 2019-12-02 Peng Cao , Jing Liu , Shuyu Tang , Andrew Leynes , Janine M. Lupo , Duan Xu , Peder E. Z. Larson

Quantification of cardiac biomarkers from cine cardiovascular magnetic resonance (CMR) data using deep learning (DL) methods offers many advantages, such as increased accuracy and faster analysis. However, only a few studies have focused on…

Quantitative Methods · Quantitative Biology 2024-08-22 Dewmini Hasara Wickremasinghe , Yiyang Xu , Esther Puyol-Antón , Paul Aljabar , Reza Razavi , Andrew P. King

Purpose: Universal Pulses (UPs) are excitation pulses that reduce the flip angle inhomogeneity in high field MRI systems without subject-specific optimization, originally developed for parallel transmit (PTX) systems at 7T. We investigated…

Multiparametric mapping MRI has become a viable tool for myocardial tissue characterization. However, misalignment between multiparametric maps makes pixel-wise analysis challenging. To address this challenge, we developed a generalizable…

Image and Video Processing · Electrical Eng. & Systems 2025-10-31 Xinqi Li , Yi Zhang , Li-Ting Huang , Hsiao-Huang Chang , Thoralf Niendorf , Min-Chi Ku , Qian Tao , Hsin-Jung Yang

Objective: we propose a procedure for calibrating 4 parameters governing the mechanical boundary conditions (BCs) of a thoracic aorta (TA) model derived from one patient with ascending aortic aneurysm. The BCs reproduce the visco-elastic…

Electrocardiography (ECG) serves as an indispensable diagnostic tool in clinical practice, yet existing multimodal large language models (MLLMs) remain unreliable for ECG interpretation, often producing plausible but clinically incorrect…

Computation and Language · Computer Science 2026-05-26 Jiarui Jin , Haoyu Wang , Xingliang Wu , Xiaocheng Fang , Xiang Lan , Zihan Wang , Deyun Zhang , Bo Liu , Yingying Zhang , Xian Wu , Hongyan Li , Shenda Hong

Quantitative magnetic resonance (MR) T1\r{ho} mapping is a promising approach for characterizing intrinsic tissue-dependent information. However, long scan time significantly hinders its widespread applications. Recently, low-rank tensor…

Image and Video Processing · Electrical Eng. & Systems 2023-01-31 Yuanyuan Liu , Dong Liang , Zhuo-Xu Cui , Yuxin Yang , Chentao Cao , Qingyong Zhu , Jing Cheng , Caiyun Shi , Haifeng Wang , Yanjie Zhu

Open gantry C-arm systems that are placed within the interventional room enable 3-D imaging and guidance for stroke therapy without patient transfer. This can profit in drastically reduced time-totherapy, however, due to the interventional…

Robust fine tuning of multi-leaf collimator (MLC) Treatment Planning System (TPS) modeling parameters is crucial for creating an optimal beam model, particularly with the ever-increasing accuracy required for advancing techniques.…

A model-based reconstruction technique for accelerated T2 mapping with improved accuracy is proposed using undersampled Cartesian spin-echo MRI data. The technique employs an advanced signal model for T2 relaxation that accounts for…

Medical Physics · Physics 2015-03-03 Tilman J. Sumpf , Andreas Petrovic , Martin Uecker , Florian Knoll , Jens Frahm

Oscillometry is the standard method for non-invasive, cuff-based blood pressure (BP) measurement, but it introduces systematic errors that may impact clinical accuracy. This study investigates the sources of these errors--primarily the…

Signal Processing · Electrical Eng. & Systems 2025-08-22 Masoud Nateghi , Reza Sameni

Purpose: This study aims to improve 0.55T T2-weighted PROPELLER lung MRI through a self-supervised joint reconstruction and denoising model. Methods: T2-weighted 0.55T lung MRI dataset including 44 patients with previous covid infection…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Jingjia Chen , Haoyang Pei , Christoph Maier , Mary Bruno , Qiuting Wen , Seon-Hi Shin , William Moore , Hersh Chandarana , Li Feng

Continuous monitoring of blood oxygen saturation levels is vital for patients with pulmonary disorders. Traditionally, SpO$_2$ monitoring has been carried out using transmittance pulse oximeters due to its dependability. However, SpO$_2$…

Signal Processing · Electrical Eng. & Systems 2020-04-15 Sricharan Vijayarangan , Prithvi Suresh , Preejith SP , Jayaraj Joseph , Mohansankar Sivaprakasam

Recent developments in cardiovascular modelling allow us to simulate blood flow in an entire human body. Such model can also be used to create databases of virtual subjects, with sizes limited only by computational resources. In this work,…

Medical Physics · Physics 2020-07-01 Janne M. J. Huttunen , Leo Kärkkäinen , Harri Lindholm

Abnormal patterns of ventricular repolarisation contribute to lethal arrhythmias in various cardiac conditions, including inherited and acquired channelopathies, cardiomyopathies, and ischaemic heart disease. However, methods to detect…

Medical Physics · Physics 2025-06-30 James A Coleman , Julia Camps , Abdallah I Hasaballa , Alfonso Bueno-Orovio