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Machine learning (ML) is transforming all areas of science. The complex and time-consuming calculations in molecular simulations are particularly suitable for a machine learning revolution and have already been profoundly impacted by the…

Chemical Physics · Physics 2019-11-11 Frank Noé , Alexandre Tkatchenko , Klaus-Robert Müller , Cecilia Clementi

Molecular dynamics (MD) has become a powerful tool for studying biophysical systems, due to increasing computational power and availability of software. Although MD has made many contributions to better understanding these complex…

Computational Physics · Physics 2019-09-27 Yihang Wang , Joao Marcelo Lamim Ribeiro , Pratyush Tiwary

Physics is living an era of unprecedented cross-fertilization among the different areas of science. In this perspective review, we discuss the manifold impact that ultracold-atom quantum technologies can have in fundamental and applied…

Quantum Physics · Physics 2024-05-13 Jorge Yago Malo , Luca Lepori , Laura Gentini , Maria Luisa Chiofalo

A force field as accurate as quantum mechanics (QM) and as fast as molecular mechanics (MM), with which one can simulate a biomolecular system efficiently enough and meaningfully enough to get quantitative insights, is among the most ardent…

Computational studies of chemical reactions in complex environments such as proteins, nanostructures, or on surfaces require accurate and efficient atomistic models applicable to the nanometer scale. In general, an accurate parametrization…

Chemical Physics · Physics 2020-02-18 Christoph Brunken , Markus Reiher

Atomistic simulations provide insights into structure-property relations on an atomic size and length scale, that are complementary to the macroscopic observables that can be obtained from experiments. Quantitative predictions, however, are…

Materials Science · Physics 2021-04-14 Nataliya Lopanitsyna , Chiheb Ben Mahmoud , Michele Ceriotti

We present PDE-FM, a modular foundation model for physics-informed machine learning that unifies spatial, spectral, and temporal reasoning across heterogeneous partial differential equation (PDE) systems. PDE-FM combines spatial-spectral…

Machine Learning · Computer Science 2025-12-01 Eduardo Soares , Emilio Vital Brazil , Victor Shirasuna , Breno W. S. R. de Carvalho , Cristiano Malossi

Understanding material failure is critical for designing stronger and lighter structures by identifying weaknesses that could be mitigated. Existing full-physics numerical simulation techniques involve trade-offs between speed, accuracy,…

Machine learning has proven to be a valuable tool to approximate functions in high-dimensional spaces. Unfortunately, analysis of these models to extract the relevant physics is never as easy as applying machine learning to a large dataset…

Materials Science · Physics 2020-05-06 Conrad W. Rosenbrock , Eric R. Homer , Gábor Csányi , Gus L. W. Hart

Recent physics foundation models claim general spatiotemporal forecasting ability, yet their evaluations often collapse performance into a single average score under a fixed training distribution. This makes it difficult to determine…

Machine Learning · Computer Science 2026-05-29 Mengdi Chu , Yang Liu , Ayan Biswas , Han-Wei Shen

Food security remains a global concern as population grows and climate change intensifies, demanding innovative solutions for sustainable agricultural productivity. Recent advances in foundation models have demonstrated remarkable…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Vishal Nedungadi , Xingguo Xiong , Aike Potze , Ron Van Bree , Tao Lin , Marc Rußwurm , Ioannis N. Athanasiadis

Molecular dynamics simulations have the potential to provide atomic-level detail and insight to important questions in chemical physics that cannot be observed in typical experiments. However, simply generating a long trajectory is…

Chemical Physics · Physics 2015-06-22 Christian R. Schwantes , Robert T. McGibbon , Vijay S. Pande

Foundational vision transformer models have shown impressive few shot performance on many vision tasks. This research presents a novel investigation into the application of parameter efficient fine-tuning methods within an active learning…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Athmanarayanan Lakshmi Narayanan , Ranganath Krishnan , Amrutha Machireddy , Mahesh Subedar

Foundation models have revolutionized artificial intelligence, setting new benchmarks in performance and enabling transformative capabilities across a wide range of vision and language tasks. However, despite the prevalence of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Adam Goodge , Wee Siong Ng , Bryan Hooi , See Kiong Ng

Over the recent years, the field of robotics has been undergoing a transformative paradigm shift from fixed, single-task, domain-specific solutions towards adaptive, multi-function, general-purpose agents, capable of operating in complex,…

The behavior of an atom in a molecule, liquid or solid is governed by the force it experiences. If the dependence of this vectorial force on the atomic chemical environment can be $learned$ efficiently with high-fidelity from benchmark…

Materials Science · Physics 2015-10-28 Venkatesh Botu , Rampi Ramprasad

The accuracy of atomistic simulations depends on the precision of force fields. Traditional numerical methods often struggle to optimize the empirical force field parameters for reproducing target properties. Recent approaches rely on…

The discovery of ferroelectricity in HfO$_2$-based thin films opens up new opportunities for using this silicon-compatible ferroelectric to realize low-power logic circuits and high-density non-volatile memories. The functional performances…

Materials Science · Physics 2021-02-03 Jing Wu , Yuzhi Zhang , Linfeng Zhang , Shi Liu

Behavioral Foundation Models (BFMs) proved successful in producing policies for arbitrary tasks in a zero-shot manner, requiring no test-time training or task-specific fine-tuning. Among the most promising BFMs are the ones that estimate…

Machine Learning · Computer Science 2026-05-05 Maksim Bobrin , Ilya Zisman , Alexander Nikulin , Vladislav Kurenkov , Dmitry Dylov

Quantum-accurate computer simulations play a central role in understanding phase-change materials (PCMs) for advanced memory technologies. However, direct quantum-mechanical simulations are necessarily limited to simplified models,…

Materials Science · Physics 2022-09-20 Yuxing Zhou , Wei Zhang , En Ma , Volker L. Deringer
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