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The quantum circuit Born machine (QCBM) is a quantum physics inspired implicit generative model naturally suitable for learning binary images, with a potential advantage of modeling discrete distributions that are hard to simulate…

Quantum Physics · Physics 2022-11-21 Pengyuan Zhai

Deep Boltzmann machines (DBMs), one of the first ``deep'' learning methods ever studied, are multi-layered probabilistic models governed by a pairwise energy function that describes the likelihood of all variables/nodes in the network. In…

Machine Learning · Computer Science 2023-07-12 Zhili Feng , Ezra Winston , J. Zico Kolter

Restricted Boltzmann Machines (RBMs) are generative models designed to learn from data with a rich underlying structure. In this work, we explore a teacher-student setting where a student RBM learns from examples generated by a teacher RBM,…

Disordered Systems and Neural Networks · Physics 2026-02-02 Gianluca Manzan , Daniele Tantari

A new approach to maximum likelihood learning of discrete graphical models and RBM in particular is introduced. Our method, Perturb and Descend (PD) is inspired by two ideas (I) perturb and MAP method for sampling (II) learning by…

Neural and Evolutionary Computing · Computer Science 2014-05-08 Siamak Ravanbakhsh , Russell Greiner , Brendan Frey

Given a quantum circuit, a quantum computer can sample the output distribution exponentially faster in the number of bits than classical computers. A similar exponential separation has yet to be established in generative models through…

Predicting and enhancing inherent properties based on molecular structures is paramount to design tasks in medicine, materials science, and environmental management. Most of the current machine learning and deep learning approaches have…

Machine Learning · Computer Science 2024-04-08 Zachary R. Fox , Ayana Ghosh

The incredible capabilities of generative artificial intelligence models have inevitably led to their application in the domain of drug discovery. Within this domain, the vastness of chemical space motivates the development of more…

Machine Learning · Computer Science 2024-02-08 Gregory W. Kyro , Anton Morgunov , Rafael I. Brent , Victor S. Batista

The deep extension of the restricted Boltzmann machine (RBM), known as the deep Boltzmann machine (DBM), is an expressive family of machine learning models which can serve as compact representations of complex probability distributions.…

Machine Learning · Computer Science 2021-02-18 Haik Manukian , Massimiliano Di Ventra

Traditional drug discovery programs are being transformed by the advent of machine learning methods. Among these, Generative AI methods (GM) have gained attention due to their ability to design new molecules and enhance specific properties…

Understanding the results of deep neural networks is an essential step towards wider acceptance of deep learning algorithms. Many approaches address the issue of interpreting artificial neural networks, but often provide divergent…

Machine Learning · Computer Science 2021-11-16 Vadim Borisov , Johannes Meier , Johan van den Heuvel , Hamed Jalali , Gjergji Kasneci

Machine learning (ML) can be used to construct surrogate models for the fast prediction of a property of interest. ML can thus be applied to chemical projects, where the usual experimentation or calculation techniques can take hours or days…

Classification of sequence data is the topic of interest for dynamic Bayesian models and Recurrent Neural Networks (RNNs). While the former can explicitly model the temporal dependencies between class variables, the latter have a capability…

Machine Learning · Computer Science 2018-03-12 Son N. Tran , Srikanth Cherla , Artur Garcez , Tillman Weyde

A model of music needs to have the ability to recall past details and have a clear, coherent understanding of musical structure. Detailed in the paper is a deep reinforcement learning architecture that predicts and generates polyphonic…

Sound · Computer Science 2018-12-05 Nikhil Kotecha

A method which casts the chemical source term computation into an artificial neural network (ANN)-inspired form is presented. This approach is well-suited for use on emerging supercomputing platforms that rely on graphical processing units…

Chemical Physics · Physics 2021-05-11 Shivam Barwey , Venkat Raman

We present a theoretical analysis of Gaussian-binary restricted Boltzmann machines (GRBMs) from the perspective of density models. The key aspect of this analysis is to show that GRBMs can be formulated as a constrained mixture of…

Neural and Evolutionary Computing · Computer Science 2017-02-06 Nan Wang , Jan Melchior , Laurenz Wiskott

Understanding the dynamics of a system is important in many scientific and engineering domains. This problem can be approached by learning state transition rules from observations using machine learning techniques. Such observed time-series…

Machine Learning · Computer Science 2022-12-08 Koji Watanabe , Katsumi Inoue

Modern deep learning has enabled unprecedented achievements in various domains. Nonetheless, employment of machine learning for wave function representations is focused on more traditional architectures such as restricted Boltzmann machines…

Quantum Physics · Physics 2019-02-20 Yoav Levine , Or Sharir , Nadav Cohen , Amnon Shashua

Deep generative models have become ubiquitous due to their ability to learn and sample from complex distributions. Despite the proliferation of various frameworks, the relationships among these models remain largely unexplored, a gap that…

Machine Learning · Computer Science 2025-10-24 J. Quetzalcóatl Toledo-Marin , Anindita Maiti , Geoffrey C. Fox , Roger G. Melko

The restricted Boltzmann machine (RBM) is used to investigate short-range order in binary alloys. The network is trained on the data collected by Monte Carlo simulations for a simple Ising-like binary alloy model and used to calculate the…

Disordered Systems and Neural Networks · Physics 2021-11-01 M. A. Timirgazin , A. K. Arzhnikov

Sampling configurations at thermodynamic equilibrium is a central challenge in statistical physics. Boltzmann Generators (BGs) tackle it by combining a generative model with a Monte Carlo (MC) correction step to obtain asymptotically…

Machine Learning · Statistics 2026-01-30 Louis Grenioux , Maxence Noble
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