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The Transformer architecture has shown a remarkable ability in modeling global relationships. However, it poses a significant computational challenge when processing high-dimensional medical images. This hinders its development and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Zhaohu Xing , Tian Ye , Yijun Yang , Guang Liu , Lei Zhu

The advent of Transformer and Mamba-based architectures has significantly advanced 3D medical image segmentation by enabling global contextual modeling, a capability traditionally limited in Convolutional Neural Networks (CNNs). However,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Duy D. Nguyen , Phat T. Tran-Truong

The adoption of Vision Transformers (ViTs) based architectures represents a significant advancement in 3D Medical Image (MI) segmentation, surpassing traditional Convolutional Neural Network (CNN) models by enhancing global contextual…

Computer Vision and Pattern Recognition · Computer Science 2024-04-25 Shehan Perera , Pouyan Navard , Alper Yilmaz

Convolutional neural networks have primarily led 3D medical image segmentation but may be limited by small receptive fields. Transformer models excel in capturing global relationships through self-attention but are challenged by high…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Ao Chang , Jiajun Zeng , Ruobing Huang , Dong Ni

U-shaped architectures have long dominated the field of medical image segmentation, while Transformers are widely employed for modeling long-range dependencies. The former typically handles scale variations implicitly by aggregating…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yanhua Zhang , Ke Zhang , Jingyu Wang , Gabriella Balestra , Samanta Rosati , Yulin Wu , Wuwei Wang , Valentina Giannini

Recently, the field of 3D medical segmentation has been dominated by deep learning models employing Convolutional Neural Networks (CNNs) and Transformer-based architectures, each with their distinctive strengths and limitations. CNNs are…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Luca Lumetti , Vittorio Pipoli , Kevin Marchesini , Elisa Ficarra , Costantino Grana , Federico Bolelli

Mamba, a special case of the State Space Model, is gaining popularity as an alternative to template-based deep learning approaches in medical image analysis. While transformers are powerful architectures, they have drawbacks, including…

Mamba, with its selective State Space Models (SSMs), offers a more computationally efficient solution than Transformers for long-range dependency modeling. However, there is still a debate about its effectiveness in high-resolution 3D…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Chaohan Wang , Yutong Xie , Qi Chen , Yuyin Zhou , Qi Wu

Accurate 3D medical image segmentation demands architectures capable of reconciling global context modeling with spatial topology preservation. While State Space Models (SSMs) like Mamba show potential for sequence modeling, existing…

Image and Video Processing · Electrical Eng. & Systems 2025-06-06 Hangyu Ji

Weakly supervised semantic segmentation offers a label-efficient solution to train segmentation models for volumetric medical imaging. However, existing approaches often rely on 2D encoders that neglect the inherent volumetric nature of the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Yiheng Lyu , Lian Xu , Mohammed Bennamoun , Farid Boussaid , Coen Arrow , Girish Dwivedi

In the domain of 3D biomedical image segmentation, Mamba exhibits the superior performance for it addresses the limitations in modeling long-range dependencies inherent to CNNs and mitigates the abundant computational overhead associated…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Weitong Wu , Zhaohu Xing , Jing Gong , Qin Peng , Lei Zhu

Sequence modeling plays a vital role across various domains, with recurrent neural networks being historically the predominant method of performing these tasks. However, the emergence of transformers has altered this paradigm due to their…

General networks for 3D medical image segmentation have recently undergone extensive exploration. Behind the exceptional performance of these networks lies a significant demand for a large volume of pixel-level annotated data, which is…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Hualiang Wang , Yiqun Lin , Xinpeng Ding , Xiaomeng Li

Convolutional Neural Networks (CNNs) and Transformers have been the most popular architectures for biomedical image segmentation, but both of them have limited ability to handle long-range dependencies because of inherent locality or…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Jun Ma , Feifei Li , Bo Wang

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Accurate microscopic medical image segmentation plays a crucial role in diagnosing various cancerous cells and identifying tumors. Driven by advancements in deep learning, convolutional neural networks (CNNs) and transformer-based models…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Daniya Najiha Abdul Kareem , Abdul Hannan , Mubashir Noman , Jean Lahoud , Mustansar Fiaz , Hisham Cholakkal

In the field of biomedical image analysis, the quest for architectures capable of effectively capturing long-range dependencies is paramount, especially when dealing with 3D image segmentation, classification, and landmark detection.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Haifan Gong , Luoyao Kang , Yitao Wang , Xiang Wan , Haofeng Li

Abnormality detection in medical imaging is a critical task requiring both high efficiency and accuracy to support effective diagnosis. While convolutional neural networks (CNNs) and Transformer-based models are widely used, both face…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Yao Wang , Dong Yang , Zhi Qiao , Wenjian Huang , Liuzhi Yang , Zhen Qian

Widely used traditional pipelines for subcortical brain segmentation are often inefficient and slow, particularly when processing large datasets. Furthermore, deep learning models face challenges due to the high resolution of MRI images and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Aaron Cao , Zongyu Li , Jordan Jomsky , Andrew F. Laine , Jia Guo

Accurate and computationally efficient 3D medical image segmentation remains a critical challenge in clinical workflows. Transformer-based architectures often demonstrate superior global contextual modeling but at the expense of excessive…

Image and Video Processing · Electrical Eng. & Systems 2026-02-19 Kavyansh Tyagi , Vishwas Rathi , Puneet Goyal
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