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Quantifying the accuracy of segmentation and manual delineation of organs, tissue types and tumors in medical images is a necessary measurement that suffers from multiple problems. One major shortcoming of all accuracy measures is that they…

Computer Vision and Pattern Recognition · Computer Science 2016-04-19 Hamid R. Tizhoosh , Ahmed A. Othman

Semantic segmentation is a core task in computer vision with applications in biomedical imaging, remote sensing, and autonomous driving. While standard loss functions such as cross-entropy and Dice loss perform well in general cases, they…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Renhao Lu

Deep learning based semi-supervised learning (SSL) methods have achieved strong performance in medical image segmentation, which can alleviate doctors' expensive annotation by utilizing a large amount of unlabeled data. Unlike most existing…

Image and Video Processing · Electrical Eng. & Systems 2022-07-26 Zihang Xu , Zhenghua Xu , Shuo Zhang , Thomas Lukasiewicz

Deep learning-based medical image segmentation techniques have shown promising results when evaluated based on conventional metrics such as the Dice score or Intersection-over-Union. However, these fully automatic methods often fail to meet…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Liu Li , Qiang Ma , Cheng Ouyang , Johannes C. Paetzold , Daniel Rueckert , Bernhard Kainz

Reliable semantic segmentation is essential for clinical decision making, yet deep models rarely provide explicit statistical guarantees on their errors. We introduce a simple post-hoc framework that constructs confidence masks with…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Luca Mossina , Corentin Friedrich

When introducing advanced image computing algorithms, e.g., whole-heart segmentation, into clinical practice, a common suspicion is how reliable the automatically computed results are. In fact, it is important to find out the failure cases…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Rongzhao Zhang , Albert C. S. Chung

Model calibration measures the agreement between the predicted probability estimates and the true correctness likelihood. Proper model calibration is vital for high-risk applications. Unfortunately, modern deep neural networks are poorly…

Image and Video Processing · Electrical Eng. & Systems 2022-09-14 Skylar E. Stolte , Kyle Volle , Aprinda Indahlastari , Alejandro Albizu , Adam J. Woods , Kevin Brink , Matthew Hale , Ruogu Fang

Semi-supervised medical image segmentation aims to leverage minimal expert annotations, yet remains confronted by challenges in maintaining high-quality consistency learning. Excessive perturbations can degrade alignment and hinder precise…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Wenbo Xiao , Zhihao Xu , Guiping Liang , Yangjun Deng , Yi Xiao

Modern medical image segmentation methods primarily use discrete representations in the form of rasterized masks to learn features and generate predictions. Although effective, this paradigm is spatially inflexible, scales poorly to…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Yejia Zhang , Pengfei Gu , Nishchal Sapkota , Danny Z. Chen

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

We propose two novel loss functions, Multiplicative Loss and Confidence-Adaptive Multiplicative Loss, for semantic segmentation in medical and cellular images. Although Cross Entropy and Dice Loss are widely used, their additive combination…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuto Yokoi , Kazuhiro Hotta

Most segmentation losses are arguably variants of the Cross-Entropy (CE) or Dice losses. On the surface, these two categories of losses seem unrelated, and there is no clear consensus as to which category is a better choice, with varying…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Bingyuan Liu , Jose Dolz , Adrian Galdran , Riadh Kobbi , Ismail Ben Ayed

Image segmentation algorithms can be understood as a collection of pixel classifiers, for which the outcomes of nearby pixels are correlated. Classifier models can be calibrated using Inductive Conformal Prediction, but this requires…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Joren Brunekreef , Eric Marcus , Ray Sheombarsing , Jan-Jakob Sonke , Jonas Teuwen

Segmentation is a key stage in dermoscopic image processing, where the accuracy of the border line that defines skin lesions is of utmost importance for subsequent algorithms (e.g., classification) and computer-aided early diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Pedro M. M. Pereira , Rui Fonseca-Pinto , Rui Pedro Paiva , Luis M. N. Tavora , Pedro A. A. Assuncao , Sergio M. M. de Faria

In clinical applications, the utility of segmentation models is often based on the accuracy of derived downstream metrics such as organ size, rather than by the pixel-level accuracy of the segmentation masks themselves. Thus, uncertainty…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Matt Y. Cheung , Ashok Veeraraghavan , Guha Balakrishnan

In weakly supervised medical image segmentation, the absence of structural priors and the discreteness of class feature distribution present a challenge, i.e., how to accurately propagate supervision signals from local to global regions…

Computer Vision and Pattern Recognition · Computer Science 2024-05-21 Yu Lei , Haolun Luo , Lituan Wang , Zhenwei Zhang , Lei Zhang

In semantic segmentation, the accuracy of models heavily depends on the high-quality annotations. However, in many practical scenarios, such as medical imaging and remote sensing, obtaining true annotations is not straightforward and…

Image and Video Processing · Electrical Eng. & Systems 2026-04-07 Ryu Tadokoro , Tsukasa Takagi , Shin-ichi Maeda

Despite remarkable advancements in pixel-level medical image perception, existing methods are either limited to specific tasks or heavily rely on accurate bounding boxes or text labels as input prompts. However, the medical knowledge…

Computer Vision and Pattern Recognition · Computer Science 2025-04-24 Qinyue Tong , Ziqian Lu , Jun Liu , Yangming Zheng , Zheming Lu

Image segmentation is a central topic in image processing and computer vision and a key issue in many applications, e.g., in medical imaging, microscopy, document analysis and remote sensing. According to the human perception, image…

Numerical Analysis · Mathematics 2022-06-24 Laura Antonelli , Valentina De Simone , Daniela di Serafino

Measuring cross-sectional areas in ultrasound images is a standard tool to evaluate disease progress or treatment response. Often addressed today with supervised deep-learning segmentation approaches, existing solutions highly depend upon…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Vanessa Gonzalez Duque , Leonhard Zirus , Yordanka Velikova , Nassir Navab , Diana Mateus