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Research has shown that deep networks tend to be overly optimistic about their predictions, leading to an underestimation of prediction errors. Due to the limited nature of data, existing studies have proposed various methods based on model…

Machine Learning · Computer Science 2023-10-24 Jia-Qi Yang , De-Chuan Zhan , Le Gan

Spatially variant dynamic convolution provides a principled approach of integrating spatial adaptivity into deep neural networks. However, mainstream designs in medical segmentation commonly generate dynamic kernels through average pooling,…

Image and Video Processing · Electrical Eng. & Systems 2026-03-02 Bo Shi , Wei-ping Zhu , M. N. S. Swamy

Fully convolutional neural networks (FCNs), and in particular U-Nets, have achieved state-of-the-art results in semantic segmentation for numerous medical imaging applications. Moreover, batch normalization and Dice loss have been used…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Alireza Mehrtash , William M. Wells , Clare M. Tempany , Purang Abolmaesumi , Tina Kapur

Reliable probabilities are critical in high-risk applications, yet common calibration criteria (confidence, class-wise) are only necessary for full distributional calibration, and post-hoc methods often lack distribution-free guarantees. We…

Machine Learning · Statistics 2025-10-17 Daniil Kazantsev , Mohsen Guizani , Eric Moulines , Maxim Panov , Nikita Kotelevskii

In semantic segmentation, even state-of-the-art deep learning models fall short of the performance required in certain high-stakes applications such as medical image analysis. In these cases, performance can be improved by allowing a model…

Machine Learning · Computer Science 2026-05-26 Bruno Laboissiere Camargos Borges , Bruno Machado Pacheco , Danilo Silva

In medical imaging, accurate image segmentation is crucial for quantifying diseases, assessing prognosis, and evaluating treatment outcomes. However, existing methods lack an in-depth integration of global and local features, failing to pay…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 Yizhi Pan , Junyi Xin , Tianhua Yang , Teeradaj Racharak , Le-Minh Nguyen , Guanqun Sun

Segmentation is a fundamental task in medical image analysis. The clinical interest is often to measure the volume of a structure. To evaluate and compare segmentation methods, the similarity between a segmentation and a predefined ground…

Image and Video Processing · Electrical Eng. & Systems 2020-10-09 Jeroen Bertels , David Robben , Dirk Vandermeulen , Paul Suetens

Topological consistency plays a crucial role in the task of boundary segmentation for reticular images, such as cell membrane segmentation in neuron electron microscopic images, grain boundary segmentation in material microscopic images and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Chuni Liu , Boyuan Ma , Xiaojuan Ban , Yujie Xie , Hao Wang , Weihua Xue , Jingchao Ma , Ke Xu

Class imbalance and the difficulty imbalance are the two types of data imbalance that affect the performance of neural networks in medical segmentation tasks. In class imbalance the loss is dominated by the majority classes and in…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Seyed Mohsen Hosseini

Medical image segmentation has played an important role in medical analysis and widely developed for many clinical applications. Deep learning-based approaches have achieved high performance in semantic segmentation but they are limited to…

Image and Video Processing · Electrical Eng. & Systems 2020-12-07 Ngan Le , Trung Le , Kashu Yamazaki , Toan Duc Bui , Khoa Luu , Marios Savides

Most machine learning-based image segmentation models produce pixel-wise confidence scores that represent the model's predicted probability for each class label at every pixel. While this information can be particularly valuable in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Bruno Viti , Elias Karabelas , Martin Holler

Probabilistic classifiers output confidence scores along with their predictions, and these confidence scores should be calibrated, i.e., they should reflect the reliability of the prediction. Confidence scores that minimize standard metrics…

This paper proposes a new metric to measure the calibration error of probabilistic binary classifiers, called test-based calibration error (TCE). TCE incorporates a novel loss function based on a statistical test to examine the extent to…

Machine Learning · Statistics 2023-06-27 Takuo Matsubara , Niek Tax , Richard Mudd , Ido Guy

Recent advances in deep learning based image segmentation methods have enabled real-time performance with human-level accuracy. However, occasionally even the best method fails due to low image quality, artifacts or unexpected behaviour of…

Medical image segmentation is usually regarded as one of the most important intermediate steps in clinical situations and medical imaging research. Thus, accurately assessing the segmentation quality of the automatically generated…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Zhenxi Zhang , Chunna Tian , Jie Li , Zhusi Zhong , Zhicheng Jiao , Xinbo Gao

Neural networks for automated image segmentation are typically trained to achieve maximum accuracy, while less attention has been given to the calibration of their confidence scores. However, well-calibrated confidence scores provide…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Axel-Jan Rousseau , Thijs Becker , Jeroen Bertels , Matthew B. Blaschko , Dirk Valkenborg

Medical image segmentation is a crucial task in medical image analysis, but it can be very challenging especially when there are less labeled data but with large unlabeled data. Contrastive learning has proven to be effective for medical…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Shihuan He , Zhihui Lai , Ruxin Wang , Heng Kong

While significant progress has been made in specifying neural networks capable of representing uncertainty, deep networks still often suffer from overconfidence and misaligned predictive distributions. Existing approaches for measuring this…

Machine Learning · Computer Science 2025-10-24 Spencer Young , Riley Sinema , Cole Edgren , Andrew Hall , Nathan Dong , Porter Jenkins

Image segmentation is a popular area of research in computer vision that has many applications in automated image processing. A recent technique called piecewise flat embeddings (PFE) has been proposed for use in image segmentation; PFE…

Computer Vision and Pattern Recognition · Computer Science 2016-12-21 Renee T. Meinhold , Tyler L. Hayes , Nathan D. Cahill

Precise lens structure segmentation is essential for the design of intraocular lenses (IOLs) in cataract surgery. Existing deep segmentation networks typically weight all pixels equally under cross-entropy (CE) loss, overlooking the fact…

Computer Vision and Pattern Recognition · Computer Science 2025-08-13 Zunjie Xiao , Xiao Wu , Tianhang Liu , Lingxi Hu , Yinling Zhang , Xiaoqing Zhang , Risa Higashita , Jiang Liu