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Automatic image segmentation is a critical component of medical image analysis, and hence quantifying segmentation performance is crucial. Challenges in medical image segmentation are mainly due to spatial variations of regions to be…

Image and Video Processing · Electrical Eng. & Systems 2021-09-09 Ammu R , Neelam Sinha

Semantic segmentation is an essential component of medical image analysis research, with recent deep learning algorithms offering out-of-the-box applicability across diverse datasets. Despite these advancements, segmentation failures remain…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Maximilian Zenk , David Zimmerer , Fabian Isensee , Jeremias Traub , Tobias Norajitra , Paul F. Jäger , Klaus Maier-Hein

Current medical image segmentation relies on the region-based (Dice, F1-score) and boundary-based (Hausdorff distance, surface distance) metrics as the de-facto standard. While these metrics are widely used, they lack a unified…

Image and Video Processing · Electrical Eng. & Systems 2024-05-15 Zheyuan Zhang , Ulas Bagci

Deep neural networks for medical image segmentation are often overconfident, compromising both reliability and clinical utility. In this work, we propose differentiable formulations of marginal L1 Average Calibration Error (mL1-ACE) as an…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Theodore Barfoot , Luis C. Garcia-Peraza-Herrera , Samet Akcay , Ben Glocker , Tom Vercauteren

The Dice similarity coefficient (DSC) is both a widely used metric and loss function for biomedical image segmentation due to its robustness to class imbalance. However, it is well known that the DSC loss is poorly calibrated, resulting in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Michael Yeung , Leonardo Rundo , Yang Nan , Evis Sala , Carola-Bibiane Schönlieb , Guang Yang

Deep neural networks for medical image segmentation often produce overconfident results misaligned with empirical observations. Such miscalibration, challenges their clinical translation. We propose to use marginal L1 average calibration…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Theodore Barfoot , Luis Garcia-Peraza-Herrera , Ben Glocker , Tom Vercauteren

The performance of medical image segmentation models is usually evaluated using metrics like the Dice score and Hausdorff distance, which compare predicted masks to ground truth annotations. However, when applying the model to unseen data,…

Image and Video Processing · Electrical Eng. & Systems 2025-04-23 Jingchen Zou , Jianqiang Li , Gabriel Jimenez , Qing Zhao , Daniel Racoceanu , Matias Cosarinsky , Enzo Ferrante , Guanghui Fu

Calibrated confidence estimates obtained from neural networks are crucial, particularly for safety-critical applications such as autonomous driving or medical image diagnosis. However, although the task of confidence calibration has been…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Fabian Küppers , Anselm Haselhoff , Jan Kronenberger , Jonas Schneider

The segmentation of medical images is a fundamental step in automated clinical decision support systems. Existing medical image segmentation methods based on supervised deep learning, however, remain problematic because of their reliance on…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Euijoon Ahn , Dagan Feng , Jinman Kim

An important issue in medical image processing is to be able to estimate not only the performances of algorithms but also the precision of the estimation of these performances. Reporting precision typically amounts to reporting…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Rosana El Jurdi , Olivier Colliot

Deploying deep learning (DL) models in medical applications relies on predictive performance and other critical factors, such as conveying trustworthy predictive uncertainty. Uncertainty estimation (UE) methods provide potential solutions…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Kudaibergen Abutalip , Numan Saeed , Ikboljon Sobirov , Vincent Andrearczyk , Adrien Depeursinge , Mohammad Yaqub

Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ke Zou , Yidi Chen , Ling Huang , Xuedong Yuan , Xiaojing Shen , Meng Wang , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

Medical image segmentation is one of the fundamental problems for artificial intelligence-based clinical decision systems. Current automatic medical image segmentation methods are often failed to meet clinical requirements. As such, a…

Computer Vision and Pattern Recognition · Computer Science 2021-11-16 Wenhao Li , Qisen Xu , Chuyun Shen , Bin Hu , Fengping Zhu , Yuxin Li , Bo Jin , Xiangfeng Wang

In medical imaging, segmentation models have known a significant improvement in the past decade and are now used daily in clinical practice. However, similar to classification models, segmentation models are affected by adversarial attacks.…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Othmane Laousy , Alexandre Araujo , Guillaume Chassagnon , Nikos Paragios , Marie-Pierre Revel , Maria Vakalopoulou

The assessment of segmentation quality plays a fundamental role in the development, optimization, and comparison of segmentation methods which are used in a wide range of applications. With few exceptions, quality assessment is performed…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Niklas Rottmayer , Claudia Redenbach

Medical image segmentation is a critical process in the field of medical imaging, playing a pivotal role in diagnosis, treatment, and research. It involves partitioning of an image into multiple regions, representing distinct anatomical or…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Charulkumar Chodvadiya , Navyansh Mahla , Kinshuk Gaurav Singh , Kshitij Sharad Jadhav

Medical image segmentation is crucial for clinical applications, but it is frequently disrupted by noisy annotations and ambiguous anatomical boundaries, limiting its application in real-world scenarios. Existing methods often directly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Chenyu Mu , Guihai Chen , Xun Yang , Erkun Yang , Cheng Deng

Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Medical image segmentation serves as a critical component of precision medicine, enabling accurate localization and delineation of pathological regions, such as lesions. However, existing models empirically apply fixed thresholds (e.g.,…

Image and Video Processing · Electrical Eng. & Systems 2025-10-22 Binyu Tan , Zhiyuan Wang , Jinhao Duan , Kaidi Xu , Heng Tao Shen , Xiaoshuang Shi , Fumin Shen

Segmentation of medical images constitutes an essential component of medical image analysis, providing the foundation for precise diagnosis and efficient therapeutic interventions in clinical practices. Despite substantial progress, most…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Muzammal Shafique , Nasir Rahim , Jamil Ahmad , Mohammad Siadat , Khalid Malik , Ghaus Malik
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