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Infectious diseases are a threat for human health with tremendous impact on our society at large. The recent COVID-19 pandemic, caused by the SARS-CoV-2, is the latest example of a highly infectious disease ravaging the world, since late…

Populations and Evolution · Quantitative Biology 2021-09-17 Giacomo Cacciapaglia , Corentin Cot , Michele Della Morte , Stefan Hohenegger , Francesco Sannino , Shahram Vatani

Multiple lines of evidence strongly suggest that infection hotspots, where a single individual infects many others, play a key role in the transmission dynamics of COVID-19. However, most of the existing epidemiological models fail to…

This work provides an overview on deterministic and stochastic models that have previously been proposed by us to study the transmission dynamics of the Coronavirus Disease 2019 (COVID-19) in Europe and USA. Briefly, we describe realistic…

Populations and Evolution · Quantitative Biology 2022-07-11 Giorgio Sonnino , Philippe Peeters , Pasquale Nardone

Within a short period of time, COVID-19 grew into a world-wide pandemic. Transmission by pre-symptomatic and asymptomatic viral carriers rendered intervention and containment of the disease extremely challenging. Based on reported infection…

Populations and Evolution · Quantitative Biology 2021-02-24 Liang Tian , Xuefei Li , Fei Qi , Qian-Yuan Tang , Viola Tang , Jiang Liu , Zhiyuan Li , Xingye Cheng , Xuanxuan Li , Yingchen Shi , Haiguang Liu , Lei-Han Tang

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

Optimization and Control · Mathematics 2020-08-20 Mauricio C. de Oliveira

An urgent problem in controlling COVID-19 spreading is to understand the role of undocumented infection. We develop a five-state model for COVID-19, taking into account the unique features of the novel coronavirus, with key parameters…

Populations and Evolution · Quantitative Biology 2020-03-27 Yong-Shang Long , Zheng-Meng Zhai , Li-Lei Han , Jie Kang , Yi-Lin Li , Zhao-Hua Lin , Lang Zeng , Da-Yu Wu , Chang-Qing Hao , Ming Tang , Zonghua Liu , Ying-Cheng Lai

Nowcasting and forecasting of epidemic spreading rely on incidence series of reported cases to derive the fundamental epidemiological parameters for a given pathogen. Two relevant drawbacks for predictions are the unknown fractions of…

Populations and Evolution · Quantitative Biology 2022-08-31 Guilherme S. Costa , Wesley Cota , Silvio C. Ferreira

We propose a novel approach that integrates machine learning into compartmental disease modeling to predict the progression of COVID-19. Our model is explainable by design as it explicitly shows how different compartments evolve and it uses…

To increase situational awareness and support evidence-based policy-making, we formulated two types of mathematical models for COVID-19 transmission within a regional population. One is a fitting function that can be calibrated to reproduce…

Novel Coronavirus disease (COVID-19) has abruptly and undoubtedly changed the world as we know it at the end of the 2nd decade of the 21st century. COVID-19 is extremely contagious and quickly spreading globally making its early diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2020-04-20 Parnian Afshar , Shahin Heidarian , Farnoosh Naderkhani , Anastasia Oikonomou , Konstantinos N. Plataniotis , Arash Mohammadi

During 2020, the infection rate of COVID-19 has been investigated by many scholars from different research fields. In this context, reliable and interpretable forecasts of disease incidents are a vital tool for policymakers to manage…

Machine Learning · Computer Science 2021-01-05 Cornelius Fritz , Emilio Dorigatti , David Rügamer

The Covid-19 pandemic is ongoing worldwide, and the damage it has caused is unprecedented. For prevention, South Korea has adopted a local quarantine strategy rather than a global lockdown. This approach not only minimizes economic damage,…

Physics and Society · Physics 2022-02-15 K. Choi , Hoyun Choi , B. Kahng

In regard to infectious diseases socioeconomic determinants are strongly associated with differential exposure and susceptibility however they are seldom accounted for by standard compartmental infectious disease models. These associations…

Applications · Statistics 2022-11-28 Alison C Hale , Jonathan M Read , Christopher P Jewell

During the COVID-19 pandemic, community containment measures have been implemented in different parts of the world. However, despite government recommendations and mandates, a progressive increase in mobility was observed in several sites.…

Physics and Society · Physics 2021-03-29 Ariel Félix Gualtieri , Pedro Hecht

The complexities involved in modelling the transmission dynamics of COVID-19 has been a roadblock in achieving predictability in the spread and containment of the disease. In addition to understanding the modes of transmission, the…

Physics and Society · Physics 2021-09-28 Ayan Paul , Jayanta Kumar Bhattacharjee , Akshay Pal , Sagar Chakraborty

Despite the progress in medical data collection the actual burden of SARS-CoV-2 remains unknown due to under-ascertainment of cases. This was apparent in the acute phase of the pandemic and the use of reported deaths has been pointed out as…

Applications · Statistics 2023-07-13 Anastasia Chatzilena , Nikolaos Demiris , Konstantinos Kalogeropoulos

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

Applications · Statistics 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

Recently, the world has witnessed the most severe pandemic (COVID-19) in this century. Studies on epidemic prediction and simulation have received increasing attention. However, the current methods suffer from three issues. First, most of…

Social and Information Networks · Computer Science 2023-03-31 Haoyu Geng , Guanjie Zheng , Zhengqing Han , Hua Wei , Zhenhui Li
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