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The emergence and spread of deadly pandemics has repeatedly occurred throughout history, causing widespread infections and loss of life. The rapid spread of pandemics have made governments across the world adopt a range of actions,…

Populations and Evolution · Quantitative Biology 2024-01-15 Marianna Karapitta , Andreas Kasis , Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

Methodology · Statistics 2022-06-17 Adam Spannaus , Theodore Papamarkou , Samantha Erwin , J. Blair Christian

We recently described a dynamic causal model of a COVID-19 outbreak within a single region. Here, we combine several of these (epidemic) models to create a (pandemic) model of viral spread among regions. Our focus is on a second wave of new…

The COVID-19 pandemic provides new motivation for a classic problem in epidemiology: estimating the empirical rate of transmission during an outbreak (formally, the time-varying reproduction number) from case counts. While standard methods…

Methodology · Statistics 2020-12-08 Bryan Wilder , Michael J. Mina , Milind Tambe

The world is currently witnessing dangerous shifts in the epidemic of emerging SARS-CoV-2, the causative agent of (COVID-19) coronavirus. The infection, and death numbers reported by World Health Organization (WHO) about this epidemic…

Cryptography and Security · Computer Science 2020-04-14 Mohamed Torky , Aboul Ella Hassanien

COVID-19 pandemic has an unprecedented impact all over the world since early 2020. During this public health crisis, reliable forecasting of the disease becomes critical for resource allocation and administrative planning. The results from…

Machine Learning · Computer Science 2021-04-07 Xiaoyong Jin , Yu-Xiang Wang , Xifeng Yan

This paper extends the canonical model of epidemiology, SIRD model, to allow for time varying parameters for real-time measurement of the stance of the COVID-19 pandemic. Time variation in model parameters is captured using the generalized…

Populations and Evolution · Quantitative Biology 2021-02-11 Cem Cakmakli , Yasin Simsek

The present paper introduces a data-driven framework for describing the time-varying nature of an SIRD model in the context of COVID-19. By embedding a rolling regression in a mixed integer bilevel nonlinear programming problem, our aim is…

Populations and Evolution · Quantitative Biology 2021-03-04 Javier Rubio-Herrero , Yuchen Wang

The widespread, and in many countries unprecedented, use of non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic has highlighted the need for mathematical models which can estimate the impact of these measures while…

A key scientific challenge during the outbreak of novel infectious diseases is to predict how the course of the epidemic changes under different countermeasures that limit interaction in the population. Most epidemiological models do not…

Physics and Society · Physics 2023-01-25 Mansi Sood , Anirudh Sridhar , Rashad Eletreby , Chai Wah Wu , Simon A. Levin , H. Vincent Poor , Osman Yagan

In this paper, we propose a new real-time differential virus transmission model, which can give more accurate and robust short-term predictions of COVID-19 transmitted infectious disease with benefits of near-term trend projection.…

Populations and Evolution · Quantitative Biology 2020-05-05 Sheldon X. D. Tan , Liang Chen

The SIR-compartment model is among the simplest models that describe the spread of a disease through a population. The model makes the unrealistic assumption that the population through which the disease is spreading is well-mixed. Although…

Populations and Evolution · Quantitative Biology 2022-11-16 Ryan Wilkinson , Marcus Roper

The coronavirus disease (COVID-19) pandemic has changed our lives and still poses a challenge to science. Numerous studies have contributed to a better understanding of the pandemic. In particular, inhalation of aerosolised pathogens has…

Populations and Evolution · Quantitative Biology 2022-09-02 Simon Rahn , Marion Gödel , Gerta Köster , Gesine Hofinger

This work aims to assess the risks of Covid-19 disease spread in diverse daily-life situations (referred to as scenarios) involving crowds of maskless pedestrians, mostly outdoors. More concretely, we develop a method to infer the global…

Physics and Society · Physics 2021-11-04 Willy Garcia , Simon Mendez , Baptiste Fray , Alexandre Nicolas

The primary tool for predicting infectious disease spread and intervention effectiveness is the mass action Susceptible-Infected-Recovered model of Kermack and McKendrick. Its usefulness derives largely from its conceptual and mathematical…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Anja C. Slim , Erik M. Volz

The surprisingly mercurial Covid-19 pandemic has highlighted the need to not only accelerate research on infectious disease, but to also study them using novel techniques and perspectives. A major contributor to the difficulty of containing…

Populations and Evolution · Quantitative Biology 2022-07-21 Aminur Rahman , Angela Peace , Ramesh Kesawan , Souparno Ghosh

The world is still fighting against COVID-19, which has been lasting for more than a year. Till date, it has been a greatest challenge to human beings in fighting against COVID-19 since, the pathogen SARS-COV-2 that causes COVID-19 has…

Populations and Evolution · Quantitative Biology 2021-06-17 P. Tamilalagan , B. Krithika , P. Manivannan

Since the start of the still ongoing COVID-19 pandemic, there have been many modeling efforts to assess several issues of importance to public health. In this work, we review the theory behind some important mathematical models that have…

Populations and Evolution · Quantitative Biology 2022-01-06 Fernando Saldaña , Jorge X Velasco-Hernández

We introduce a methodology to guarantee safety against the spread of infectious diseases by viewing epidemiological models as control systems and by considering human interventions (such as quarantining or social distancing) as control…

Systems and Control · Electrical Eng. & Systems 2022-11-21 Tamas G. Molnar , Andrew W. Singletary , Gabor Orosz , Aaron D. Ames

In this research, we study the propagation patterns of epidemic diseases such as the COVID-19 coronavirus, from a mathematical modeling perspective. The study is based on an extensions of the well-known susceptible-infected-recovered (SIR)…

Populations and Evolution · Quantitative Biology 2021-01-01 Reza Sameni