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Cancer prognosis is a critical task that involves predicting patient outcomes and survival rates. To enhance prediction accuracy, previous studies have integrated diverse data modalities, such as clinical notes, medical images, and genomic…

Machine Learning · Computer Science 2025-02-04 Jie Peng , Shuang Zhou , Longwei Yang , Yiran Song , Mohan Zhang , Kaixiong Zhou , Feng Xie , Mingquan Lin , Rui Zhang , Tianlong Chen

Multimodal learning seeks to utilize data from multiple sources to improve the overall performance of downstream tasks. It is desirable for redundancies in the data to make multimodal systems robust to missing or corrupted observations in…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Md Kaykobad Reza , Ashley Prater-Bennette , M. Salman Asif

Integrating the different data modalities of cancer patients can significantly improve the predictive performance of patient survival. However, most existing methods ignore the simultaneous utilization of rich semantic features at different…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Liangrui Pan , Yijun Peng , Yan Li , Yiyi Liang , Liwen Xu , Qingchun Liang , Shaoliang Peng

Generating multi-contrasts/modal MRI of the same anatomy enriches diagnostic information but is limited in practice due to excessive data acquisition time. In this paper, we propose a novel deep-learning model for joint reconstruction and…

Image and Video Processing · Electrical Eng. & Systems 2022-06-30 Wanyu Bian , Qingchao Zhang , Xiaojing Ye , Yunmei Chen

In the domain of multimedia and multimodal processing, the efficient handling of diverse data streams such as images, video, and sensor data is paramount. Model compression and multitask learning (MTL) are crucial in this field, offering…

Computer Vision and Pattern Recognition · Computer Science 2024-08-08 Mingcan Xiang , Steven Jiaxun Tang , Qizheng Yang , Hui Guan , Tongping Liu

Unsupervised anomaly detection aims to build models to effectively detect unseen anomalies by only training on the normal data. Although previous reconstruction-based methods have made fruitful progress, their generalization ability is…

Machine Learning · Computer Science 2022-01-04 Yuxin Zhang , Jindong Wang , Yiqiang Chen , Han Yu , Tao Qin

We propose cross-modal attentive connections, a new dynamic and effective technique for multimodal representation learning from wearable data. Our solution can be integrated into any stage of the pipeline, i.e., after any convolutional…

Machine Learning · Computer Science 2022-06-10 Anubhav Bhatti , Behnam Behinaein , Paul Hungler , Ali Etemad

Currently intelligent diagnosis systems lack the ability of continually learning to diagnose new diseases once deployed, under the condition of preserving old disease knowledge. In particular, updating an intelligent diagnosis system with…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Wentao Zhang , Yujun Huang , Tong Zhang , Qingsong Zou , Wei-Shi Zheng , Ruixuan Wang

The choice of input text prompt plays a critical role in the performance of Vision-Language Pretrained (VLP) models such as CLIP. We present APoLLo, a unified multi-modal approach that combines Adapter and Prompt learning for…

Machine Learning · Computer Science 2023-12-05 Sanjoy Chowdhury , Sayan Nag , Dinesh Manocha

In multi-party collaborative learning, the parameter server sends a global model to each data holder for local training and then aggregates committed models globally to achieve privacy protection. However, both the dragger issue of…

Machine Learning · Computer Science 2021-06-29 Guangmeng Zhou , Ke Xu , Qi Li , Yang Liu , Yi Zhao

The use of diverse modalities, such as omics, medical images, and clinical data can not only improve the performance of prognostic models but also deepen an understanding of disease mechanisms and facilitate the development of novel…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Maria Boyko , Aleksandra Beliaeva , Dmitriy Kornilov , Alexander Bernstein , Maxim Sharaev

Accurate survival prediction is crucial for development of precision cancer medicine, creating the need for new sources of prognostic information. Recently, there has been significant interest in exploiting routinely collected clinical and…

Machine Learning · Computer Science 2021-03-23 Sejin Kim , Michal Kazmierski , Benjamin Haibe-Kains

Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

Image and Video Processing · Electrical Eng. & Systems 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie

This paper proposes a novel discriminative regression method, called adaptive locality preserving regression (ALPR) for classification. In particular, ALPR aims to learn a more flexible and discriminative projection that not only preserves…

Computer Vision and Pattern Recognition · Computer Science 2019-01-04 Jie Wen , Zuofeng Zhong , Zheng Zhang , Lunke Fei , Zhihui Lai , Runze Chen

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Multimodal learning that integrates histopathology images and genomic data holds great promise for cancer survival prediction. However, existing methods face key limitations: 1) They rely on multimodal mapping and metrics in Euclidean…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Jiaqi Yang , Wenting Chen , Xiaohan Xing , Sean He , Xiaoling Luo , Xinheng Lyu , Linlin Shen , Guoping Qiu

Adaptive therapy (AT) is designed to postpone the emergence of drug resistance by exploiting evolutionary competition among tumor subclones. Most mathematical models of AT assume a binary population structure of drug-sensitive and…

Populations and Evolution · Quantitative Biology 2026-05-19 Rui Yue , Chenghang Li , Jinzhi Lei

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang

Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

Quantitative Methods · Quantitative Biology 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

Major pathological response (pR) following neoadjuvant therapy is a clinically meaningful endpoint in non-small cell lung cancer, strongly associated with improved survival. However, accurate preoperative prediction of pR remains…