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Modern language models often rely on Reinforcement Learning from Human Feedback (RLHF) to encourage safe behaviors. However, they remain vulnerable to adversarial attacks due to three key limitations: (1) the inefficiency and high cost of…

Recent advances in computational pathology and artificial intelligence have significantly enhanced the utilization of gigapixel whole-slide images and and additional modalities (e.g., genomics) for pathological diagnosis. Although deep…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Qichen Sun , Zhengrui Guo , Rui Peng , Hao Chen , Jinzhuo Wang

Multi-modal learning, which focuses on utilizing various modalities to improve the performance of a model, is widely used in video recognition. While traditional multi-modal learning offers excellent recognition results, its computational…

Computer Vision and Pattern Recognition · Computer Science 2021-05-13 Rameswar Panda , Chun-Fu Chen , Quanfu Fan , Ximeng Sun , Kate Saenko , Aude Oliva , Rogerio Feris

Accurate cancer survival prediction requires integration of diverse data modalities that reflect the complex interplay between imaging, clinical parameters, and textual reports. However, existing multimodal approaches suffer from simplistic…

Machine Learning · Computer Science 2025-07-01 Aakash Tripathi , Asim Waqas , Matthew B. Schabath , Yasin Yilmaz , Ghulam Rasool

Deep learning based analysis of histopathology images shows promise in advancing the understanding of tumor progression, tumor micro-environment, and their underpinning biological processes. So far, these approaches have focused on…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Adalberto Claudio Quiros , Nicolas Coudray , Anna Yeaton , Wisuwat Sunhem , Roderick Murray-Smith , Aristotelis Tsirigos , Ke Yuan

This work addresses challenges in evaluating adaptive artificial intelligence (AI) models for medical devices, where iterative updates to both models and evaluation datasets complicate performance assessment. We introduce a novel approach…

Artificial Intelligence · Computer Science 2026-04-07 Alexis Burgon , Berkman Sahiner , Nicholas A Petrick , Gene Pennello , Ravi K Samala

Multimodal Federated Learning (MFL) with mixed modalities enables unimodal and multimodal clients to collaboratively train models while ensuring clients' privacy. As a representative sample of local data, prototypes offer an approach with…

Machine Learning · Computer Science 2025-08-05 Keke Gai , Mohan Wang , Jing Yu , Dongjue Wang , Qi Wu

Morphological attributes from histopathological images and molecular profiles from genomic data are important information to drive diagnosis, prognosis, and therapy of cancers. By integrating these heterogeneous but complementary data, many…

Machine Learning · Computer Science 2022-02-28 Kaiwen Tan , Weixian Huang , Xiaofeng Liu , Jinlong Hu , Shoubin Dong

Multimodal models trained on complete modality data often exhibit a substantial decrease in performance when faced with imperfect data containing corruptions or missing modalities. To address this robustness challenge, prior methods have…

Multimedia · Computer Science 2023-10-24 Mengxi Chen , Jiangchao Yao , Linyu Xing , Yu Wang , Ya Zhang , Yanfeng Wang

Breast cancer remains a leading cause of cancer-related mortality worldwide. Early detection is critical, yet manual histopathology analysis is complex and subject to inter-observer variability. While deep neural network-based diagnostic…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Gul Sheeraz , Qun Chen , Liu Feiyu , Zhou Fengjin

Visual instruction datasets from various distributors are released at different times and often contain a significant number of semantically redundant text-image pairs, depending on their task compositions (i.e., skills) or reference…

Machine Learning · Computer Science 2025-03-25 Adyasha Maharana , Jaehong Yoon , Tianlong Chen , Mohit Bansal

Survival prediction plays a crucial role in assisting clinicians with the development of cancer treatment protocols. Recent evidence shows that multimodal data can help in the diagnosis of cancer disease and improve survival prediction.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Ruiquan Ge , Xiangyang Hu , Rungen Huang , Gangyong Jia , Yaqi Wang , Renshu Gu , Changmiao Wang , Elazab Ahmed , Linyan Wang , Juan Ye , Ye Li

Cross-domain few-shot classification induces a much more challenging problem than its in-domain counterpart due to the existence of domain shifts between the training and test tasks. In this paper, we develop a novel Adaptive Parametric…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Marzi Heidari , Abdullah Alchihabi , Qing En , Yuhong Guo

To improve the prediction of cancer survival using whole-slide images and transcriptomics data, it is crucial to capture both modality-shared and modality-specific information. However, multimodal frameworks often entangle these…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Aniek Eijpe , Soufyan Lakbir , Melis Erdal Cesur , Sara P. Oliveira , Sanne Abeln , Wilson Silva

The current cancer treatment practice collects multimodal data, such as radiology images, histopathology slides, genomics and clinical data. The importance of these data sources taken individually has fostered the recent raise of radiomics…

Machine Learning · Computer Science 2023-06-16 Matteo Tortora , Ermanno Cordelli , Rosa Sicilia , Lorenzo Nibid , Edy Ippolito , Giuseppe Perrone , Sara Ramella , Paolo Soda

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

Machine Learning · Computer Science 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Multimodal survival methods combining gigapixel histology whole-slide images (WSIs) and transcriptomic profiles are particularly promising for patient prognostication and stratification. Current approaches involve tokenizing the WSIs into…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Andrew H. Song , Richard J. Chen , Guillaume Jaume , Anurag J. Vaidya , Alexander S. Baras , Faisal Mahmood

This paper focuses on the task of survival time analysis for lung cancer. Although much progress has been made in this problem in recent years, the performance of existing methods is still far from satisfactory. Traditional and some deep…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Yujiao Wu , Yaxiong Wang , Xiaoshui Huang , Fan Yang , Sai Ho Ling , Steven Weidong Su

While vision-and-language models significantly advance in many fields, the challenge of continual learning is unsolved. Parameter-efficient modules like adapters and prompts present a promising way to alleviate catastrophic forgetting.…

Machine Learning · Computer Science 2024-10-16 Hong Li , Zhiquan Tan , Xingyu Li , Weiran Huang

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu