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Related papers: Large Language Models in Bioinformatics: A Survey

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Large Language Models (LLMs) deliver powerful AI capabilities but face deployment challenges due to high resource costs and latency, whereas Small Language Models (SLMs) offer efficiency and deployability at the cost of reduced performance.…

Artificial Intelligence · Computer Science 2025-05-13 Yi Chen , JiaHao Zhao , HaoHao Han

This research paper discusses the advances made in the past decade in biomedicine and Large Language Models. To understand how the advances have been made hand-in-hand with one another, the paper also discusses the integration of Natural…

Computation and Language · Computer Science 2024-06-26 Michael Ackerman

The adoption of large language models (LLMs) to assist clinicians has attracted remarkable attention. Existing works mainly adopt the close-ended question-answering (QA) task with answer options for evaluation. However, many clinical…

The ever-increasing workload of digital forensic labs raises concerns about law enforcement's ability to conduct both cyber-related and non-cyber-related investigations promptly. Consequently, this article explores the potential and…

Cryptography and Security · Computer Science 2025-02-03 Akila Wickramasekara , Frank Breitinger , Mark Scanlon

Speech understanding is essential for interpreting the diverse forms of information embedded in spoken language, including linguistic, paralinguistic, and non-linguistic cues that are vital for effective human-computer interaction. The…

Audio and Speech Processing · Electrical Eng. & Systems 2025-12-08 Jing Peng , Yucheng Wang , Bohan Li , Yiwei Guo , Hankun Wang , Yangui Fang , Yu Xi , Haoyu Li , Xu Li , Ke Zhang , Shuai Wang , Kai Yu

In the rapidly evolving field of large language models (LLMs), data augmentation (DA) has emerged as a pivotal technique for enhancing model performance by diversifying training examples without the need for additional data collection. This…

Computation and Language · Computer Science 2024-07-03 Bosheng Ding , Chengwei Qin , Ruochen Zhao , Tianze Luo , Xinze Li , Guizhen Chen , Wenhan Xia , Junjie Hu , Anh Tuan Luu , Shafiq Joty

Large Language Models (LLMs) are increasingly applied in the fields of mechanical engineering and materials science. As models that establish connections through the interface of language, LLMs can be applied for step-wise reasoning through…

Applied Physics · Physics 2025-07-22 Adrian Ehrenhofer , Thomas Wallmersperger , Gianaurelio Cuniberti

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

Optimization algorithms and large language models (LLMs) enhance decision-making in dynamic environments by integrating artificial intelligence with traditional techniques. LLMs, with extensive domain knowledge, facilitate intelligent…

Neural and Evolutionary Computing · Computer Science 2024-05-17 Sen Huang , Kaixiang Yang , Sheng Qi , Rui Wang

Large Language Models (LLMs) have become a milestone in the field of artificial intelligence and natural language processing. However, their large-scale deployment remains constrained by the need for significant computational resources.…

Computation and Language · Computer Science 2025-08-07 Julián Camilo Velandia Gutiérrez

The impact of Transformer-based language models has been unprecedented in Natural Language Processing (NLP). The success of such models has also led to their adoption in other fields including bioinformatics. Taking this into account, this…

Machine Learning · Computer Science 2025-07-21 Nimisha Ghosh , Daniele Santoni , Debaleena Nawn , Eleonora Ottaviani , Giovanni Felici

Large language models (LLMs) are complex artificial intelligence systems capable of understanding, generating and translating human language. They learn language patterns by analyzing large amounts of text data, allowing them to perform…

Cryptography and Security · Computer Science 2024-03-15 Biwei Yan , Kun Li , Minghui Xu , Yueyan Dong , Yue Zhang , Zhaochun Ren , Xiuzhen Cheng

Recent years have witnessed remarkable progress made in large language models (LLMs). Such advancements, while garnering significant attention, have concurrently elicited various concerns. The potential of these models is undeniably vast;…

Computation and Language · Computer Science 2023-09-27 Tianhao Shen , Renren Jin , Yufei Huang , Chuang Liu , Weilong Dong , Zishan Guo , Xinwei Wu , Yan Liu , Deyi Xiong

Emerging topics in biomedical research are continuously expanding, providing a wealth of information about genes and their function. This rapid proliferation of knowledge presents unprecedented opportunities for scientific discovery and…

Genomics · Quantitative Biology 2024-12-25 Zhijian Chen , Chuan Hu , Min Wu , Qingqing Long , Xuezhi Wang , Yuanchun Zhou , Meng Xiao

Large Language Models (LLMs) have introduced a paradigm shift in interaction with AI technology, enabling knowledge workers to complete tasks by specifying their desired outcome in natural language. LLMs have the potential to increase…

Human-Computer Interaction · Computer Science 2025-03-24 Michelle Brachman , Amina El-Ashry , Casey Dugan , Werner Geyer

In the rapidly evolving landscape of artificial intelligence (AI), generative large language models (LLMs) stand at the forefront, revolutionizing how we interact with our data. However, the computational intensity and memory consumption of…

Machine Learning · Computer Science 2025-07-24 Xupeng Miao , Gabriele Oliaro , Zhihao Zhang , Xinhao Cheng , Hongyi Jin , Tianqi Chen , Zhihao Jia

The rapid advances of large language models (LLMs), such as ChatGPT, are revolutionizing data science and statistics. These state-of-the-art tools can streamline complex processes. As a result, it reshapes the role of data scientists. We…

Computers and Society · Computer Science 2023-07-10 Xinming Tu , James Zou , Weijie J. Su , Linjun Zhang

Large Language Models (LLMs) are increasingly adopted as conversational assistants in genomics, where they are mainly used to reason over biological knowledge, annotations, and analysis outputs through natural language interfaces. However,…

Genomics · Quantitative Biology 2026-04-08 Weicai Long , Yusen Hou , Junning Feng , Houcheng Su , Shuo Yang , Donglin Xie , Yanlin Zhang

With the advancement of Artificial Intelligence (AI) and Large Language Models (LLMs), there is a profound transformation occurring in the realm of natural language processing tasks within the legal domain. The capabilities of LLMs are…

Computation and Language · Computer Science 2024-04-02 Weicong Qin , Zhongxiang Sun

Natural Language Processing (NLP) is witnessing a remarkable breakthrough driven by the success of Large Language Models (LLMs). LLMs have gained significant attention across academia and industry for their versatile applications in text…

Computation and Language · Computer Science 2024-04-16 Taojun Hu , Xiao-Hua Zhou