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Quantum computers and simulators may offer significant advantages over their classical counterparts, providing insights into quantum many-body systems and possibly improving performance for solving exponentially hard problems, such as…

Quantum optimization allows for up to exponential quantum speedups for specific, possibly industrially relevant problems. As the key algorithm in this field, we motivate and discuss the Quantum Approximate Optimization Algorithm (QAOA),…

Quantum Physics · Physics 2025-11-18 Jonas Stein , Maximilian Zorn , Leo Sünkel , Thomas Gabor

We introduce a quantum approximate optimization algorithm (QAOA) for continuous optimization. The algorithm is based on the dynamics of a quantum system moving in an energy potential which encodes the objective function. By approximating…

Quantum Physics · Physics 2019-02-04 Guillaume Verdon , Juan Miguel Arrazola , Kamil Brádler , Nathan Killoran

Optimization is often cited as a promising application of quantum computers. However, the low degree of provable quantum speedups has led prior rigorous end-to-end resource analyses to conclude that a quantum computer is unlikely to surpass…

Molecular docking is an important tool for structure-based drug design, accelerating the efficiency of drug development. Complex and dynamic binding processes between proteins and small molecules require searching and sampling over a wide…

Chemical Physics · Physics 2024-02-23 Runqiu Shu , Bowen Liu , Zhaoping Xiong , Xiaopeng Cui , Yunting Li , Wei Cui , Man-Hong Yung , Nan Qiao

The quantum approximate optimization algorithm (QAOA) has been introduced as a heuristic digital quantum computing scheme to find approximate solutions of combinatorial problems with shallow circuits. We present a scheme to parallelize this…

Quantum Physics · Physics 2018-03-02 Wolfgang Lechner

The ability of the Quantum Approximate Optimization Algorithm (QAOA) to deliver a quantum advantage on combinatorial optimization problems is still unclear. Recently, a scaling advantage over a classical solver was postulated to exist for…

Quantum Physics · Physics 2024-12-02 Thorge Müller , Ajainderpal Singh , Frank K. Wilhelm , Tim Bode

The quantum approximate optimisation algorithm (QAOA) is a hybrid quantum-classical algorithm used to approximately solve combinatorial optimisation problems. It involves multiple iterations of a parameterised ansatz comprising a problem…

Quantum Physics · Physics 2024-02-16 V. Vijendran , Aritra Das , Dax Enshan Koh , Syed M. Assad , Ping Koy Lam

Quantum Approximate Optimization Algorithm (QAOA) is a hybrid algorithm whose control parameters are classically optimized. In addition to the variational parameters, the right choice of hyperparameter is crucial for improving the…

Quantum Physics · Physics 2022-06-30 Yu Pan , Yifan Tong , Yi Yang

The Quantum Approximate Optimization Algorithm (QAOA) requires considered optimization problems to be translated into a compatible format. A popular transformation step in this pipeline involves the quadratization of higher-order binary…

Quantum Physics · Physics 2025-11-26 Damian Rovara , Lukas Burgholzer , Robert Wille

The Quantum Approximate Optimisation Algorithm (QAOA) is a widely studied quantum-classical iterative heuristic for combinatorial optimisation. While QAOA targets problems in complexity class NP, the classical optimisation procedure…

Quantum Physics · Physics 2025-11-12 Tom Krüger , Wolfgang Mauerer

The Quantum Approximate Optimisation Algorithm (QAOA) is a hybrid quantum-classical algorithm for solving combinatorial optimisation problems. QAOA encodes solutions into the ground state of a Hamiltonian, approximated by a $p$-level…

Quantum Physics · Physics 2025-05-16 V Vijendran , Dax Enshan Koh , Eunok Bae , Hyukjoon Kwon , Ping Koy Lam , Syed M Assad

The quantum approximate optimization algorithm (QAOA) has numerous promising applications in solving the combinatorial optimization problems on near-term Noisy Intermediate Scalable Quantum (NISQ) devices. QAOA has a quantum-classical…

Quantum Physics · Physics 2022-02-17 Xinwei Lee , Yoshiyuki Saito , Dongsheng Cai , Nobuyoshi Asai

The Quantum Approximate Optimization Algorithm (QAOA) represents a significant opportunity for practical quantum computing applications, particularly in the era before error correction is fully realized. This algorithm is especially…

Quantum Physics · Physics 2024-10-08 Yiwen Liu , Qingyue Jiao , Yidong Zhou , Zhiding Liang , Yiyu Shi , Ke Wan , Shangjie Guo

The quantum approximate optimization algorithm (QAOA) is a leading iterative variational quantum algorithm for heuristically solving combinatorial optimization problems. A large portion of the computational effort in QAOA is spent by the…

Quantum Physics · Physics 2022-08-23 Ohad Amosy , Tamuz Danzig , Ely Porat , Gal Chechik , Adi Makmal

We present a classical control mechanism for Quantum devices using Reinforcement Learning. Our strategy is applied to the Quantum Approximate Optimization Algorithm (QAOA) in order to optimize an objective function that encodes a solution…

Quantum Physics · Physics 2019-11-25 Artur Garcia-Saez , Jordi Riu

Maximum cut (Max-Cut) problem is one of the most important combinatorial optimization problems because of its various applications in real life, and recently Quantum Approximate Optimization Algorithm (QAOA) has been widely employed to…

Quantum Physics · Physics 2023-07-31 Yiren Lu , Guojing Tian , Xiaoming Sun

We explore the application of variational quantum algorithms to the NP-hard set balancing problem, a critical challenge in clinical trial design and experimental scheduling. The problem is mapped to an Ising model, with tailored Quadratic…

Quantum Physics · Physics 2025-09-10 Nikhil Kowshik , Sayan Manna , Sudebkumar Prasant Pal

Hybrid quantum-classical algorithms such as the Quantum Approximate Optimization Algorithm (QAOA) are considered as one of the most encouraging approaches for taking advantage of near-term quantum computers in practical applications. Such…

The quantum approximate optimization algorithm (QAOA) is a quantum heuristic for combinatorial optimization that has been demonstrated to scale better than state-of-the-art classical solvers for some problems. For a given problem instance,…

Quantum Physics · Physics 2026-02-23 Tianyi Hao , Zichang He , Ruslan Shaydulin , Jeffrey Larson , Marco Pistoia
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