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Related papers: Spatially-Structured Models of Viral Dynamics: A S…

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Understanding the dynamics of the spread of diseases within populations is critical for effective public health interventions. We extend the classical SIR model by incorporating additional complexities such as the introduction of a cure and…

Populations and Evolution · Quantitative Biology 2025-10-30 Daniel Perkins , Davis Hunter , Drake Brown , Trevor Garrity , Wyatt Pochman

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

In recent years, generative diffusion models have achieved a rapid paradigm shift in deep generative models by showing groundbreaking performance across various applications. Meanwhile, structured data, encompassing tabular and time series…

Machine Learning · Computer Science 2023-07-11 Heejoon Koo , To Eun Kim

We present a new technique for rapid modeling and construction of scientifically accurate mesoscale biological models. Resulting 3D models are based on few 2D microscopy scans and the latest knowledge about the biological entity represented…

The growth of cities has traditionally been studied from a population perspective, while urban expansion-its spatial growth-has often been approached qualitatively. However, characterizing and modeling this spatial expansion is crucial,…

Physics and Society · Physics 2026-03-31 Ulysse Marquis , Marc Barthelemy

Biochemical networks play a crucial role in biological systems, implementing a broad range of vital functions. They normally operate at low copy numbers and in spatial settings, but this is often ignored and well-stirred conditions are…

Molecular Networks · Quantitative Biology 2017-05-25 Thomas R. Sokolowski , Pieter Rein ten Wolde

Infectious disease models can be of great use for understanding the underlying mechanisms that influence the spread of diseases and predicting future disease progression. Modeling has been increasingly used to evaluate the potential impact…

Applications · Statistics 2019-08-20 Md Mahsin , Rob Deardon , Patrick Brown

Pandemic management requires that scientists rapidly formulate and analyze epidemiological models in order to forecast the spread of disease and the effects of mitigation strategies. Scientists must modify existing models and create novel…

Programming Languages · Computer Science 2022-10-12 Sophie Libkind , Andrew Baas , Micah Halter , Evan Patterson , James Fairbanks

The increase in the connectivity between hosts in recent times has facilitated the emergence of more aggressive mutant viral strains, making their containment and eradication significantly more challenging compared to the original variants.…

Populations and Evolution · Quantitative Biology 2025-02-27 Javier López-Pedrares , M. Elena Vázquez-Cendón , Alberto P. Muñuzuri

Spatiotemporal modelling of infectious diseases such as COVID-19 involves using a variety of epidemiological metrics such as regional proportion of cases or regional positivity rates. Although observing their changes over time is critical…

Spatial self-organization emerges in distributed systems exhibiting local interactions when nonlinearities and the appropriate propagation of signals are at work. These kinds of phenomena can be modeled with different frameworks, typically…

Cell Behavior · Quantitative Biology 2016-11-23 Adriano Bonforti , Salva Duran-Nebreda , Raul Montañez , Ricard Solé

Understanding large amounts of spatiotemporal data from particle-based simulations, such as molecular dynamics, often relies on the computation and analysis of aggregate measures. These, however, by virtue of aggregation, hide structural…

Computational Physics · Physics 2019-10-10 Juraj Pálenik , Jan Byška , Stefan Bruckner , Helwig Hauser

Spatiotemporal data mining (STDM) discovers useful patterns from the dynamic interplay between space and time. Several available surveys capture STDM advances and report a wealth of important progress in this field. However, STDM challenges…

Machine Learning · Computer Science 2021-04-01 Ali Hamdi , Khaled Shaban , Abdelkarim Erradi , Amr Mohamed , Shakila Khan Rumi , Flora Salim

Understanding the dissemination of diseases, information, and behavior stands as a paramount research challenge in contemporary network and complex systems science. The COVID-19 pandemic and the proliferation of misinformation are relevant…

Physics and Society · Physics 2024-02-26 Guilherme Ferraz de Arruda , Alberto Aleta , Yamir Moreno

Drug development is a wide scientific field that faces many challenges these days. Among them are extremely high development costs, long development times, as well as a low number of new drugs that are approved each year. To solve these…

Biomolecules · Quantitative Biology 2022-11-08 Christoph Gorgulla

Epidemic spread on networks is one of the most studied dynamics in network science and has important implications in real epidemic scenarios. Nonetheless, the dynamics of real epidemics and how it is affected by the underline structure of…

Physics and Society · Physics 2020-09-08 Bnaya Gross , Shlomo Havlin

The scientific rigor and computational methods of causal inference have had great impacts on many disciplines, but have only recently begun to take hold in spatial applications. Spatial casual inference poses analytic challenges due to…

Methodology · Statistics 2020-07-07 Brian J Reich , Shu Yang , Yawen Guan , Andrew B Giffin , Matthew J Miller , Ana G Rappold

Context: The globalisation of activities associated with software development and use has introduced many challenges in practice and for research. While the predominant approach to research in software engineering has followed a positivist…

Software Engineering · Computer Science 2021-02-01 Tony Clear , Stephen G. MacDonell

With the advancement of computational network science, its research scope has significantly expanded beyond static graphs to encompass more complex structures. The introduction of streaming, temporal, multilayer, and hypernetwork approaches…

Social and Information Networks · Computer Science 2024-05-29 Michał Czuba , Mateusz Nurek , Damian Serwata , Yu-Xuan Qiu , Mingshan Jia , Katarzyna Musial , Radosław Michalski , Piotr Bródka

Viral kinetics have been extensively studied in the past through the use of spatially well-mixed ordinary differential equations describing the time evolution of the diseased state. However, emerging spatial structures such as localized…

Cell Behavior · Quantitative Biology 2024-04-02 Catherine Beauchemin