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Background and Objective: To assess the feasibility and accuracy of reconstructing time-resolved, three-dimensional, subject-specific aortic geometries from a limited number of standard cine 2D magnetic resonance imaging (MRI) acquisitions.…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Gloria Wolkerstorfer , Stefano Buoso , Rabea Schlenker , Jochen von Spiczak , Robert Manka , Sebastian Kozerke

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Intracranial aneurysms (IAs) are serious cerebrovascular lesions found in approximately 5\% of the general population. Their rupture may lead to high mortality. Current methods for assessing IA risk focus on morphological and…

The rupture of an abdominal aortic aneurysm (AAA) is associated with a high mortality. When an AAA ruptures, 50% of the patients die before reaching the hospital. Of the patients that are able to reach the operating room, only 50% have it…

Applications · Statistics 2015-08-21 Rafael Izbicki , Ann B. Lee , Ender A. Finol

We propose a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features like retinal…

The exact shape of intracranial aneurysms is critical in medical diagnosis and surgical planning. While voxel-based deep learning frameworks have been proposed for this segmentation task, their performance remains limited. In this study, we…

Image and Video Processing · Electrical Eng. & Systems 2021-07-06 Xi Yang , Ding Xia , Taichi Kin , Takeo Igarashi

Pre-operative Abdominal Aortic Aneurysm (AAA) 3D shape is critical for customized stent-graft design in Fenestrated Endovascular Aortic Repair (FEVAR). Traditional segmentation approaches implement expert-designed feature extractors while…

Computer Vision and Pattern Recognition · Computer Science 2018-04-10 Jian-Qing Zheng , Xiao-Yun Zhou , Qing-Biao Li , Celia Riga , Guang-Zhong Yang

The surface morphology of the developing mammalian brain is crucial for understanding brain function and dysfunction. Computational modeling offers valuable insights into the underlying mechanisms for early brain folding. Recent findings…

Neurons and Cognition · Quantitative Biology 2024-09-06 Jixin Hou , Zhengwang Wu , Xianyan Chen , Li Wang , Dajiang Zhu , Tianming Liu , Gang Li , Xianqiao Wang

Abdominal aortic aneurysm (AAA) wall stress is a candidate rupture risk marker but is typically computed from single-phase images without known cardiac phase. Linear stress recovery methods, which solve a single geometrically linear…

Medical Physics · Physics 2025-11-25 Alastair Catlin , Mostafa Jamshidian , Adam Wittek , Karol Miller

Intrasaccular flow disruptors treat cerebral aneurysms by diverting the blood flow from the aneurysm sac. Residual flow into the sac after the intervention is a failure that could be due to the use of an undersized device, or to vascular…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Ashutosh Jadhav , Satyananda Kashyap , Hakan Bulu , Ronak Dholakia , Amon Y. Liu , Tanveer Syeda-Mahmood , William R. Patterson , Hussain Rangwala , Mehdi Moradi

Representing 3D shape deformations by linear models in high-dimensional space has many applications in computer vision and medical imaging, such as shape-based interpolation or segmentation. Commonly, using Principal Components Analysis a…

Computer Vision and Pattern Recognition · Computer Science 2016-05-12 Florian Bernard , Peter Gemmar , Frank Hertel , Jorge Goncalves , Johan Thunberg

Particle-based shape modeling (PSM) is a family of approaches that automatically quantifies shape variability across anatomical cohorts by positioning particles (pseudo landmarks) on shape surfaces in a consistent configuration. Recent…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Hong Xu , Shireen Y. Elhabian

We propose a deep learning-based technique for detection and quantification of abdominal aortic aneurysms (AAAs). The condition, which leads to more than 10,000 deaths per year in the United States, is asymptomatic, often detected…

Cerebral aneurysms are pathological dilations of intracranial arteries that can rupture with devastating consequences, including subarachnoid hemorrhage, stroke, and death. Accumulating evidence indicates that local hemodynamic forces play…

Other Quantitative Biology · Quantitative Biology 2025-05-22 Reza Bozorgpour , Pilwan Kim

Abdominal aortic aneurysm (AAA) is a life-threatening condition characterized by the progressive dilation of the aorta, which can lead to rupture if undetected or untreated. Stress-based rupture risk estimation using computational…

Predicting rupture risk and deciding on optimal treatment plan for intracranial aneurysms (IAs) is possible by quantification of their size and shape. For this purpose the IA has to be isolated from 3D angiogram. State-of-the-art methods…

Image and Video Processing · Electrical Eng. & Systems 2020-06-01 Žiga Bizjak , Boštjan Likar , Franjo Pernuš , Žiga Špiclin

This study aims to mitigate these biases and enhance QA analysis by applying a path-length correction (PLC) correction, followed by singular value decomposition (SVD)-based deconvolution, to angiograms obtained through both in-silico and…

Progressive aneurysmal dilatation is a well-recognized complication in patients with chronic type B aortic dissection (cTBAD), which may lead to a delayed rupture and create a life-threatening condition. However, our understanding of such…

Typical approaches to patient-specific hemodynamic studies of cerebral aneurysms use image based computational fluid dynamics (CFD) and seek to statistically correlate parameters such as wall shear stress (WSS) and oscillatory shear index…

Abdominal aortic aneurysm (AAA) is a vascular disease in which a section of the aorta enlarges, weakening its walls and potentially rupturing the vessel. Abdominal ultrasound has been utilized for diagnostics, but due to its limited image…

Image and Video Processing · Electrical Eng. & Systems 2022-08-12 Yordanka Velikova , Walter Simson , Mehrdad Salehi , Mohammad Farid Azampour , Philipp Paprottka , Nassir Navab