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Mixed-integer nonlinear programs (MINLPs) arise in domains such as energy systems, process engineering, and transportation, and are notoriously difficult to solve at scale due to the interplay of discrete decisions and nonlinear…

Machine Learning · Computer Science 2025-12-16 Bo Tang , Elias B. Khalil , Ján Drgoňa

Combinatorial sequential decision making problems are typically modeled as mixed integer linear programs (MILPs) and solved via branch and bound (B&B) algorithms. The inherent difficulty of modeling MILPs that accurately represent…

Artificial Intelligence · Computer Science 2025-12-15 Akhil S Anand , Elias Aarekol , Martin Mziray Dalseg , Magnus Stalhane , Sebastien Gros

Mixed-Integer Linear Programming (MILP) is a powerful framework used to address a wide range of NP-hard combinatorial optimization problems, often solved by Branch and Bound (B&B). A key factor influencing the performance of B&B solvers is…

Machine Learning · Computer Science 2025-10-23 Paul Strang , Zacharie Alès , Côme Bissuel , Olivier Juan , Safia Kedad-Sidhoum , Emmanuel Rachelson

While Mixed-integer linear programming (MILP) is NP-hard in general, practical MILP has received roughly 100--fold speedup in the past twenty years. Still, many classes of MILPs quickly become unsolvable as their sizes increase, motivating…

Machine Learning · Computer Science 2023-05-29 Ziang Chen , Jialin Liu , Xinshang Wang , Jianfeng Lu , Wotao Yin

Planning in hybrid systems with both discrete and continuous control variables is important for dealing with real-world applications such as extra-planetary exploration and multi-vehicle transportation systems. Meanwhile, generating…

Robotics · Computer Science 2021-02-23 Jingkai Chen , Brian Williams , Chuchu Fan

Mixed-integer linear programs (MILPs) are extensively used to model practical problems such as planning and scheduling. A prominent method for solving MILPs is large neighborhood search (LNS), which iteratively seeks improved solutions…

Optimization and Control · Mathematics 2024-12-12 Wenbo Liu , Akang Wang , Wenguo Yang , Qingjiang Shi

Inspection planning is concerned with computing the shortest robot path to inspect a given set of points of interest (POIs) using the robot's sensors. This problem arises in a wide range of applications from manufacturing to medical…

Robotics · Computer Science 2026-05-12 Adir Morgan , Kiril Solovey , Oren Salzman

Finding optimal join orders is among the most crucial steps to be performed by query optimisers. Though extensively studied in data management research, the problem remains far from solved: While query optimisers rely on exhaustive search…

Databases · Computer Science 2025-10-24 Manuel Schönberger , Immanuel Trummer , Wolfgang Mauerer

Integer linear programming (ILP) is an elegant approach to solve linear optimization problems, naturally described using integer decision variables. Within the context of physics-inspired machine learning applied to chemistry, we…

We present an integrated prediction-optimization (PredOpt) framework to efficiently solve sequential decision-making problems by predicting the values of binary decision variables in an optimal solution. We address the key issues of…

Machine Learning · Computer Science 2023-11-14 Dogacan Yilmaz , İ. Esra Büyüktahtakın

Over the past few decades, neuroscience experiments have become increasingly complex and naturalistic. Experimental design has in turn become more challenging, as experiments must conform to an ever-increasing diversity of design…

Neurons and Cognition · Quantitative Biology 2020-12-07 Storm Slivkoff , Jack L. Gallant

This paper presents a new hybrid classical-quantum approach to solve Mixed Integer Linear Programming (MILP) using neutral atom quantum computations. We apply Benders decomposition (BD) to segment MILPs into a master problem (MP) and a…

Quantum Physics · Physics 2024-07-17 M. Yassine Naghmouchi , Wesley da Silva Coelho

Optimization modeling via mixed-integer linear programming (MILP) is fundamental to industrial planning and scheduling, yet translating natural-language requirements into solver-executable models and maintaining them under evolving business…

Artificial Intelligence · Computer Science 2026-03-24 Yiliu He , Tianle Li , Binghao Ji , Zhiyuan Liu , Di Huang

We address the optimal design of a large scale multi-agent system where each agent has discrete and/or continuous decision variables that need to be set so as to optimize the sum of linear local cost functions, in presence of linear local…

Optimization and Control · Mathematics 2017-06-28 Alessandro Falsone , Kostas Margellos , Maria Prandini

In this paper we solve mixed-integer linear programs (MILPs) via distributed asynchronous saddle point computation. This work is motivated by the MILPs being able to model problems in multi-agent autonomy, such as task assignment problems…

Optimization and Control · Mathematics 2024-10-16 Luke Fina , Christopher Petersen , Matthew Hale

Data-driven inverse optimization for mixed-integer linear programs (MILPs), which seeks to learn an objective function and constraints consistent with observed decisions, is important for building accurate mathematical models in a variety…

Optimization and Control · Mathematics 2026-02-17 Akira Kitaoka

We consider integer programming problems with bounded general-integer variables belonging to the general class of network flow problems. For those, we computationally investigate the effect on mixed-integer linear programming (MIP) solvers…

Optimization and Control · Mathematics 2026-04-09 Pierre Bonami , Sanjeeb Dash , Anton Derkach , Andrea Lodi

Mixed-integer linear programming (MILP), a widely used modeling framework for combinatorial optimization, are central to many scientific and engineering applications, yet remains computationally challenging at scale. Recent advances in deep…

Artificial Intelligence · Computer Science 2026-01-09 Peixin Huang , Yaoxin Wu , Yining Ma , Cathy Wu , Wen Song , Wei Zhang

This paper aims to predict optimal solutions for combinatorial optimization problems (COPs) via machine learning (ML). To find high-quality solutions efficiently, existing work uses a ML prediction of the optimal solution to guide heuristic…

Optimization and Control · Mathematics 2023-01-30 Yunzhuang Shen , Yuan Sun , Xiaodong Li , Andrew Eberhard , Andreas Ernst

This paper addresses the problem of tightening the mixed-integer linear programming (MILP) formulation for continuous piecewise linear (CPWL) approximations of data sets in arbitrary dimensions. The MILP formulation leverages the…

Optimization and Control · Mathematics 2026-01-08 Quentin Ploussard , Xiang Li , Matija Pavičević