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Recent studies in pathology foundation models have shown that scaling training data, diversifying cancer types, and increasing model size consistently improve their performance. However, giga-scale foundation models, which are trained on…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Yesung Cho , Sungmin Lee , Geongyu Lee , Minkyung Lee , Jongbae Park , Dongmyung Shin

The emergence of pathology foundation models has revolutionized computational histopathology, enabling highly accurate, generalized whole-slide image analysis for improved cancer diagnosis, and prognosis assessment. While these models show…

With the development of deep convolutional neural networks, medical image segmentation has achieved a series of breakthroughs in recent years. However, the high-performance convolutional neural networks always mean numerous parameters and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-30 Wenxuan Zou , Muyi Sun

Computational pathology has made significant progress in recent years, fueling advances in both fundamental disease understanding and clinically ready tools. This evolution is driven by the availability of large amounts of digitized slides…

Recent rapid progress in the field of computational pathology has been enabled by foundation models. These models are beginning to move beyond encoding image patches towards whole-slide understanding but their clinical utility remains…

As natural image understanding moves towards the pretrain-finetune era, research in pathology imaging is concurrently evolving. Despite the predominant focus on pretraining pathological foundation models, how to adapt foundation models to…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Jiaxuan Lu , Fang Yan , Xiaofan Zhang , Yue Gao , Shaoting Zhang

Healthcare foundation models have largely followed paradigms from natural language processing and computer vision, emphasizing large scale pretraining and deterministic representations over heterogeneous clinical data. However, clinical…

Machine Learning · Computer Science 2026-04-07 Qian Zhou , Yuanyun Zhang , Shi Li

Medical image segmentation is crucial for computer-aided diagnosis, yet privacy constraints hinder data sharing across institutions. Federated learning addresses this limitation, but existing approaches often rely on lightweight…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Tong Wang , Xingyue Zhao , Linghao Zhuang , Haoyu Zhao , Jiayi Yin , Yuyang He , Gang Yu , Bo Lin

Deep metric learning aims to transform input data into an embedding space, where similar samples are close while dissimilar samples are far apart from each other. In practice, samples of new categories arrive incrementally, which requires…

Computer Vision and Pattern Recognition · Computer Science 2022-03-11 Gao-Dong Liu , Wan-Lei Zhao , Jie Zhao

Accurate medical image segmentation is essential for effective diagnosis and treatment planning but is often challenged by domain shifts caused by variations in imaging devices, acquisition conditions, and patient-specific attributes.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Jie Bao , Zhixin Zhou , Wen Jung Li , Rui Luo

Accurate semantic segmentation for histopathology image is crucial for quantitative tissue analysis and downstream clinical modeling. Recent segmentation foundation models have improved generalization through large-scale pretraining, yet…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Peixian Liang , Songhao Li , Shunsuke Koga , Yutong Li , Zahra Alipour , Yucheng Tang , Daguang Xu , Zhi Huang

Pathology image analysis plays a pivotal role in medical diagnosis, with deep learning techniques significantly advancing diagnostic accuracy and research. While numerous studies have been conducted to address specific pathological tasks,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-31 Dankai Liao , Sicheng Chen , Nuwa Xi , Qiaochu Xue , Jieyu Li , Lingxuan Hou , Zeyu Liu , Chang Han Low , Yufeng Wu , Yiling Liu , Yanqin Jiang , Dandan Li , Shangqing Lyu

Recent advancements in deep learning have shifted the development of brain imaging analysis. However, several challenges remain, such as heterogeneity, individual variations, and the contradiction between the high dimensionality and small…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Yanwu Yang , Hairui Chen , Jiesi Hu , Xutao Guo , Ting Ma

While pathology foundation models have transformed cancer image analysis, they often lack integration with molecular data at single-cell resolution, limiting their utility for precision oncology. Here, we present PAST, a pan-cancer…

Quantitative Methods · Quantitative Biology 2025-07-10 Changchun Yang , Haoyang Li , Yushuai Wu , Yilan Zhang , Yifeng Jiao , Yu Zhang , Rihan Huang , Yuan Cheng , Yuan Qi , Xin Guo , Xin Gao

Data sharing in the medical image analysis field has potential yet remains underappreciated. The aim is often to share datasets efficiently with other sites to train models effectively. One possible solution is to avoid transferring the…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Muyang Li , Can Cui , Quan Liu , Ruining Deng , Tianyuan Yao , Marilyn Lionts , Yuankai Huo

Recently, many foundation models for medical image analysis such as MedSAM, SwinUNETR have been released and proven to be useful in multiple tasks. However, considering the inherent heterogeneity and inhomogeneity of real-world medical…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Shangde Gao , Yichao Fu , Ke Liu , Hongxia Xu , Jian Wu

The fusion of complementary multimodal information is crucial in computational pathology for accurate diagnostics. However, existing multimodal learning approaches necessitate access to users' raw data, posing substantial privacy risks.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yuanzhe Peng , Jieming Bian , Jie Xu

In recent years, foundation models such as CLIP, DINO,and CONCH have demonstrated remarkable domain generalization and unsupervised feature extraction capabilities across diverse imaging tasks. However, systematic and independent…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Lavish Ramchandani , Aashay Tinaikar , Dev Kumar Das , Rohit Garg , Tijo Thomas

The scarcity of well-annotated medical datasets requires leveraging transfer learning from broader datasets like ImageNet or pre-trained models like CLIP. Model soups averages multiple fine-tuned models aiming to improve performance on…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Santosh Sanjeev , Nuren Zhaksylyk , Ibrahim Almakky , Anees Ur Rehman Hashmi , Mohammad Areeb Qazi , Mohammad Yaqub

Tabular foundation models (TFMs) achieve strong performance on health datasets, but their inference cost and infrastructure requirements limit practical use. We study whether their predictive behavior can be transferred to lightweight…

Machine Learning · Computer Science 2026-05-19 Aditya Tanna , Nassim Bouarour , Mohamed Bouadi , Vinay Kumar Sankarapu , Pratinav Seth
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