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In clinical practice, many diagnosis tasks rely on the identification of cells in histopathology images. While supervised machine learning techniques require labels, providing manual cell annotations is time-consuming due to the large…

This paper presents a new scalable algorithm for cross-modal similarity preserving retrieval in a learnt manifold space. Unlike existing approaches that compromise between preserving global and local geometries, the proposed technique…

Computer Vision and Pattern Recognition · Computer Science 2016-12-20 Sailesh Conjeti , Anees Kazi , Nassir Navab , Amin Katouzian

With the increasing multimedia information, multimodal recommendation has received extensive attention. It utilizes multimodal information to alleviate the data sparsity problem in recommendation systems, thus improving recommendation…

Information Retrieval · Computer Science 2024-03-01 Jinfeng Xu , Zheyu Chen , Shuo Yang , Jinze Li , Hewei Wang , Edith C. -H. Ngai

Self-Supervised Learning (SSL) methods harness the concept of semantic invariance by utilizing data augmentation strategies to produce similar representations for different deformations of the same input. Essentially, the model captures the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Huijie Guo , Ying Ba , Jie Hu , Lingyu Si , Wenwen Qiang , Lei Shi

Timely and accurate lymphoma diagnosis is essential for guiding cancer treatment. Standard diagnostic practice combines hematoxylin and eosin (HE)-stained whole slide images with immunohistochemistry, flow cytometry, and molecular genetic…

Breast cancer has the highest mortality among cancers in women. Computer-aided pathology to analyze microscopic histopathology images for diagnosis with an increasing number of breast cancer patients can bring the cost and delays of…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Abhijeet Patil , Dipesh Tamboli , Swati Meena , Deepak Anand , Amit Sethi

Thyroid cancer is currently the fifth most common malignancy diagnosed in women. Since differentiation of cancer sub-types is important for treatment and current, manual methods are time consuming and subjective, automatic computer-aided…

Multimodal feature reconstruction is a promising approach for 3D anomaly detection, leveraging the complementary information from dual modalities. We further advance this paradigm by utilizing multi-modal mentor learning, which fuses…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Hanzhe Liang

Multi-modal brain tumor segmentation typically involves four magnetic resonance imaging (MRI) modalities, while incomplete modalities significantly degrade performance. Existing solutions employ explicit or implicit modality adaptation,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Kaixiang Yang , Wenqi Shan , Xudong Li , Xuan Wang , Xikai Yang , Xi Wang , Pheng-Ann Heng , Qiang Li , Zhiwei Wang

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents a more difficult scenario. To cope with this challenge, Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Tianyi Liu , Zhaorui Tan , Muyin Chen , Xi Yang , Haochuan Jiang , Kaizhu Huang

The integration of Artificial Intelligence (AI) into pathology faces a fundamental challenge: black-box predictive models lack transparency, while generative approaches risk clinical hallucination. A case-based retrieval paradigm offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Qifeng Zhou , Wenliang Zhong , Thao M. Dang , Hehuan Ma , Saiyang Na , Yuzhi Guo , Junzhou Huang

Molecular property prediction aims to learn representations that map chemical structures to functional properties. While multimodal learning has emerged as a powerful paradigm to learn molecular representations, prior works have largely…

Machine Learning · Computer Science 2026-03-03 Feng Jiang , Mangal Prakash , Hehuan Ma , Jianyuan Deng , Yuzhi Guo , Amina Mollaysa , Tommaso Mansi , Rui Liao , Junzhou Huang

Representation learning on electronic health records (EHRs) plays a vital role in downstream medical prediction tasks. Although natural language processing techniques, such as recurrent neural networks, and self-attention, have been adapted…

Artificial Intelligence · Computer Science 2026-01-12 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Chengqi Zhang , Allison Clarke , Clement Schlegel

Multimodal models integrating natural language and visual information have substantially improved generalization of representation models. However, their effectiveness significantly declines in real-world situations where certain modalities…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Jiajun Chen , Sai Cheng , Yutao Yuan , Yirui Zhang , Haitao Yuan , Peng Peng , Yi Zhong

Multimodal deep learning (MDL) has emerged as a transformative approach in computational pathology. By integrating complementary information from multiple data sources, MDL models have demonstrated superior predictive performance across…

Quantitative Methods · Quantitative Biology 2025-11-17 Seth Alain Chang , Muhammad Mueez Amjad , Noorul Wahab , Ethar Alzaid , Nasir Rajpoot , Adam Shephard

Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…

Machine Learning · Computer Science 2016-11-18 Hamid Reza Hassanzadeh , John H. Phan , May D. Wang

Multiple instance learning exhibits a powerful approach for whole slide image-based diagnosis in the absence of pixel- or patch-level annotations. In spite of the huge size of hole slide images, the number of individual slides is often…

Generating radiology reports automatically reduces the workload of radiologists and helps the diagnoses of specific diseases. Many existing methods take this task as modality transfer process. However, since the key information related to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Yitian Tao , Liyan Ma , Jing Yu , Han Zhang

Multiple instance (MI) learning with a convolutional neural network enables end-to-end training in the presence of weak image-level labels. We propose a new method for aggregating predictions from smaller regions of the image into an…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Heather D. Couture , J. S. Marron , Charles M. Perou , Melissa A. Troester , Marc Niethammer

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr