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In this paper the first equation within a class of well known chemotaxis systems is derived as a hydrodynamic limit from a stochastic interacting many particle system on the lattice. The cells are assumed to interact with attractive…

Probability · Mathematics 2018-04-26 Stefan Grosskinsky , Daniel Marahrens , Angela Stevens

We generated a computational approach to analyze the biomechanics of epithelial cell aggregates, either island or stripes or entire monolayers, that combines both vertex and contact-inhibition-of-locomotion models to include both cell-cell…

In this paper homogenization of a mathematical model for biomechanics of a plant tissue with randomly distributed cells is considered. Mechanical properties of a plant tissue are modelled by a strongly coupled system of…

Analysis of PDEs · Mathematics 2020-10-28 Andrey Piatnitski , Mariya Ptashnyk

Plants often exhibit regular arrangements of seeds or leaves, known as phyllotaxis, and can famously exhibit Fibonacci spirals, as in sunflower heads or on pine cones. While there are many models which can reproduce spiral formation, the…

Biological Physics · Physics 2025-09-09 Michael F. Staddon

Chemotaxis systems play a crucial role in modeling the dynamics of bacterial and cellular behaviors, including propagation, aggregation, and pattern formation, all under the influence of chemical signals. One notable characteristic of these…

Numerical Analysis · Mathematics 2024-02-07 Alina Chertock , Shumo Cui , Alexander Kurganov , Chenxi Wang

We study the stationary Keller--Segel chemotaxis models with logistic cellular growth over a one-dimensional region subject to the Neumann boundary condition. We show that nonconstant solutions emerge in the sense of Turing's instability as…

Analysis of PDEs · Mathematics 2016-04-19 Qi Wang , Jingda Yan , Chunyi Gai

A stochastic walker model is proposed to describe the chemotactic guidance of growth cones, i.e. the tips of developing neurites. The model accounts for the influence of both attractive and repulsive chemical cues, which are emitted by the…

Analysis of PDEs · Mathematics 2025-11-04 Noah Geltner , Ansgar Jüngel

In this paper we consider kinetic and associated macroscopic models for chemotaxis on a network. Coupling conditions at the nodes of the network for the kinetic problem are presented and used to derive coupling conditions for the…

Analysis of PDEs · Mathematics 2015-12-29 Raul Borsche , Axel Klar , Ha T. N. Pham

Graph-based signal processing techniques have become essential for handling data in non-Euclidean spaces. However, there is a growing awareness that these graph models might need to be expanded into `higher-order' domains to effectively…

Machine Learning · Computer Science 2024-04-15 Mustafa Hajij , Ghada Zamzmi , Theodore Papamarkou , Aldo Guzmán-Sáenz , Tolga Birdal , Michael T. Schaub

Colonies of bacteria grown on thin agar plate exhibit fractal patterns as a result of adaptation to their environments. The bacterial colony pattern formation is regulated crucially by chemotaxis, the movement of cells along a chemical…

Biological Physics · Physics 2013-05-24 Waipot Ngamsaad , Kannika Khompurngson

Complex biological and physical transport processes are often described through systems of interacting particles. Excluded-volume effects on these transport processes are well studied, however the interplay between volume exclusion and…

Statistical Mechanics · Physics 2018-06-27 Daniel Wilson , Helen Byrne , Maria Bruna

When a single cell senses a chemical gradient and chemotaxes, stochastic receptor-ligand binding can be a fundamental limit to the cell's accuracy. For clusters of cells responding to gradients, however, there is a critical difference: even…

Cell Behavior · Quantitative Biology 2017-11-09 Brian A. Camley , Wouter-Jan Rappel

Cooperative search games are collective tasks where all agents share the same goal of reaching a target in the shortest time while limiting energy expenditure and avoiding collisions. Here we show that the equations that characterize the…

Biological Physics · Physics 2018-10-10 Alberto Pezzotta , Matteo Adorisio , Antonio Celani

The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth,…

Biological Physics · Physics 2024-04-10 Johannes C. Krämer , Edouard Hannezo , Gerhard Gompper , Jens Elgeti

A dynamic model for cell differentiation is studied, where cells with internal chemical reaction dynamics interact with each other and replicate. It leads to spontaneous differentiation of cells and determination, as is discussed in the…

adap-org · Physics 2007-05-23 Chikara Furusawa , Kunihiko Kaneko

Spatial distributions of morphogens provide positional information in developing systems, but how the distributions are established and maintained remains an open problem. Transport by diffusion has been the traditional mechanism, but…

Cell Behavior · Quantitative Biology 2022-11-23 Jay A. Stotsky , Hans G. Othmer

The organization of cells within tissues plays a vital role in various biological processes, including development and morphogenesis. As a result, understanding how cells self-organize in tissues has been an active area of research. In our…

Soft Condensed Matter · Physics 2023-10-09 Kanaya Malakar , Rafael I. Rubenstein , Dapeng Bi , Bulbul Chakraborty

Kinetic-transport equations that take into account the intra-cellular pathways are now considered as the correct description of bacterial chemotaxis by run and tumble. Recent mathematical studies have shown their interest and their…

Analysis of PDEs · Mathematics 2018-06-13 Benoît Perthame , Weiran Sun , Min Tang

The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…

Biological Physics · Physics 2019-09-04 Matteo Campo , Simon K. Schnyder , John J. Molina , Thomas Speck , Ryoichi Yamamoto

We consider an inertial model of chemotactic aggregation generalizing the Keller-Segel model and we study the linear dynamical stability of an infinite and homogeneous distribution of cells (bacteria, amoebae, endothelial cells,...) when…

Biological Physics · Physics 2009-11-13 Pierre-Henri Chavanis