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Chemotaxis describes the intricate interplay of cellular motion in response to a chemical signal. We here consider the case of slab geometry which models chemotactic motion between two infinite membranes. Like previous works, we are…

Analysis of PDEs · Mathematics 2026-01-16 Herbert Egger , Kathrin Hellmuth , Nora Philippi , Matthias Schlottbom

This paper studies a chemotaxis system where cells move in response to a chemical signal within a confined habitat. The model includes external source terms that combine local and nonlocal growth with dampening effects. The main focus is on…

Analysis of PDEs · Mathematics 2025-11-11 Rafael Diaz Fuentes , Fatma Gamze Duzgun , Silvia Frassu , Giuseppe Viglialoro

Chemotaxis, i.e. motion generated by chemical gradients, is a motility mode shared by many living species that has been developed by evolution to optimize certain biological processes such as foraging or immune response. In particular,…

Soft Condensed Matter · Physics 2023-05-24 Hugues Meyer , Heiko Rieger

Chemical signaling is one of the ubiquitous mechanisms by which inter-cellular communication takes place at the microscopic level, particularly via chemotaxis. Such multi-cellular systems are popularly studied using continuum, mean-field…

Cell Behavior · Quantitative Biology 2009-11-11 Ramon Grima

Cells perform directed motion in response to external stimuli that they detect by sensing the environment with their membrane protrusions. In particular, several biochemical and biophysical cues give rise to tactic migration in the…

Cell Behavior · Quantitative Biology 2020-07-15 N. Loy , M. Conte

Three-dimensional cultures of cells are gaining popularity as an in vitro improvement over 2D Petri dishes. In many such experiments, cells have been found to organize in aggregates. We present new results of three-dimensional in vitro…

Cell Behavior · Quantitative Biology 2018-11-01 Federica Bubba , Camille Pouchol , Nathalie Ferrand , Guillaume Vidal , Luis Almeida , Benoıt Perthame , Michèle Sabbah

The long range movement of certain organisms in the presence of a chemoattractant can be governed by long distance runs, according to an approximate Levy distribution. This article clarifies the form of biologically relevant model…

Biological Physics · Physics 2018-04-12 Gissell Estrada-Rodriguez , Heiko Gimperlein , Kevin J. Painter

Chemotaxis plays a significant role in numerous physiological processes. The Keller-Segel equation serves as a mathematical model for simulating the phenomenon of cell population aggregation under chemotaxis, possessing physical properties…

Numerical Analysis · Mathematics 2025-02-24 Mingmei Chen , Kun Wang , Cong Xie

As a class of nonlinear partial differential equations, the Keller-Segel system is widely used to model chemotaxis in biology. In this paper, we present the construction and analysis of a decoupled linear, mass-conservative, block-centered…

Numerical Analysis · Mathematics 2025-01-24 Jie Xu , Hongfei Fu

We consider the chemotaxis problem for a one-dimensional system. To analyze the interaction of bacteria and attractant we use a modified Keller-Segel model which accounts attractant absorption. To describe the system we use the chemotaxis…

Biological Physics · Physics 2017-02-15 Alex Vasilev

Populations can become spatially organised through chemotaxis autoattraction, wherein population members release their own chemoattractant. Standard models of this process usually assume phenotypic homogeneity, but recent studies have shed…

Populations and Evolution · Quantitative Biology 2025-06-05 Tommaso Lorenzi , Kevin J. Painter

Chemotaxis-driven invasions have been proposed across a broad spectrum of biological processes, from cancer to ecology. The influential system of equations introduced by Keller and Segel has proven a popular choice in the modelling of such…

Populations and Evolution · Quantitative Biology 2022-02-02 Tommaso Lorenzi , Kevin J Painter

Multicellular chemotaxis can occur via individually chemotaxing cells that are mechanically coupled. Alternatively, it can emerge collectively, from cells chemotaxing differently in a group than they would individually. Here we consider…

Biological Physics · Physics 2017-11-01 Julien Varennes , Sean Fancher , Bumsoo Han , Andrew Mugler

In this paper, we address a distributed control problem for a system of partial differential equations describing the evolution of a tumor that takes the biological mechanism of chemotaxis into account. The system describing the evolution…

Optimization and Control · Mathematics 2023-09-19 Gianni Gilardi , Andrea Signori , Jürgen Sprekels

In this paper we deal with diffusive relaxation limits of nonlinear systems of Euler type modeling chemotactic movement of cells toward Keller--Segel type systems. The approximating systems are either hyperbolic--parabolic or…

Analysis of PDEs · Mathematics 2008-07-25 M. Di Francesco , D. Donatelli

The large scale behaviour of a population of cells that grow and interact through the concentration field of the chemicals they secrete is studied using dynamical renormalization group methods. The combination of the effective long-range…

Cell Behavior · Quantitative Biology 2015-01-19 Anatolij Gelimson , Ramin Golestanian

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

Biological Physics · Physics 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

Aerotaxis is the particular form of chemotaxis in which oxygen plays the role of both the attractant and the repellent. Aerotaxis occurs without methylation adaptation, and it leads to fast and complete aggregation toward the most favorable…

Classical Analysis and ODEs · Mathematics 2015-06-26 Barbara "Bori" C. Mazzag

Cells are constantly exposed to diverse stimuli-chemical, mechanical, or electrical-that guide their movement. In physiological conditions, these signals often overlap, as seen during infections, where neutrophils and dendritic cells…

Biological Physics · Physics 2026-03-25 Emiliano Perez Ipiña , Brian A. Camley

The capacity to aggregate through chemosensitive movement forms a paradigm of self-organisation, with examples spanning cellular and animal systems. A basic mechanism assumes a phenotypically homogeneous population that secretes its own…

Analysis of PDEs · Mathematics 2022-09-26 Fiona R Macfarlane , Tommaso Lorenzi , Kevin J Painter