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Understanding how distributed brain regions coordinate to produce behavior requires models that are both predictive and interpretable. We introduce Behavior-Adaptive Connectivity Estimation (BACE), an end-to-end framework that learns…

Neurons and Cognition · Quantitative Biology 2025-10-27 Mehrnaz Asadi , Sina Javadzadeh , Rahil Soroushmojdehi , S. Alireza Seyyed Mousavi , Terence D. Sanger

The study's objective is to explore the distinctions in the functional brain network connectivity between Alzheimer's Disease (AD) patients and normal controls using Functional Magnetic Resonance Imaging (fMRI). The study included 590…

Neurons and Cognition · Quantitative Biology 2023-05-17 Yongcheng Yao

Brain connectomics is a developing field in neurosciences which strives to understand cognitive processes and psychiatric diseases through the analysis of interactions between brain regions. However, in the high-dimensional, low-sample, and…

Applications · Statistics 2019-11-15 Claire Donnat , Leonardo Tozzi , Susan Holmes

This paper develops a novel statistical approach to characterize temporally localised cross-oscillatory interactions between channels in a functional brain network. Brain signals are generally nonstationary and the proposed framework uses…

Methodology · Statistics 2026-02-10 Haibo Wu , Marina I. Knight , Hernando Ombao

This study introduces a pioneering approach in brain-computer interface (BCI) technology, featuring our novel concept of high-level visual imagery for non-invasive electroencephalography (EEG)-based communication. High-level visual imagery,…

Human-Computer Interaction · Computer Science 2025-11-03 Byoung-Hee Kwon , Minji Lee , Seong-Whan Lee

Neurodegenerative diseases and traumatic brain injuries (TBI) are among the main causes of cognitive dysfunction in humans. Both manifestations exhibit the extensive presence of focal axonal swellings (FAS). FAS compromises the information…

Neurons and Cognition · Quantitative Biology 2016-09-27 Melanie Weber , Pedro D. Maia , J. Nathan Kutz

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

In this article, we introduce a novel problem of audio-visual autism behavior recognition, which includes social behavior recognition, an essential aspect previously omitted in AI-assisted autism screening research. We define the task at…

This paper considers joint analysis of multiple functionally related structures in classification tasks. In particular, our method developed is driven by how functionally correlated brain structures vary together between autism and control…

Machine Learning · Statistics 2021-09-08 Zhiyuan Liu , Jörn Schulz , Mohsen Taheri , Martin Styner , James Damon , Stephen Pizer , J. S. Marron

Population analyses of functional connectivity have provided a rich understanding of how brain function differs across time, individual, and cognitive task. An important but challenging task in such population analyses is the identification…

Social and Information Networks · Computer Science 2020-08-19 James D. Wilson , Melanie Baybay , Rishi Sankar , Paul Stillman , Abbie M. Popa

Evaluating the causal effect of an intervention on multivariate outcomes is challenging when the outcomes are interdependent and derived rather than directly observed. Effective connectivity, which summarizes the directional neural…

Methodology · Statistics 2026-04-02 Haiyue Song , Ani Eloyan , Youjin Lee

Functional brain network has been widely studied to understand the relationship between brain organization and behavior. In this paper, we aim to explore the functional connectivity of brain network under a \emph{multi-step} cognitive task…

Neurons and Cognition · Quantitative Biology 2017-12-06 Shi-Min Cai , Wei Chen , Dong-Bai Liu , Ming Tang , Xun Chen

In this article, we study association between the structural connectome and cognitive profiles using a multi-response nonparametric regression model.The cognitive profiles are measured in terms of seven age-adjusted cognitive test scores.…

Methodology · Statistics 2022-12-06 Arkaprava Roy

We propose an integrated deep-generative framework, that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract predictive biomarkers of a…

A major challenge in neuroimaging is understanding the mapping of neurophysiological dynamics onto cognitive functions. Traditionally, these maps have been constructed by examining changes in the activity magnitude of regions related to…

Delineating the associations between images and a vector of covariates is of central interest in medical imaging studies. To tackle this problem of image response regression, we propose a novel nonparametric approach in the framework of…

Machine Learning · Statistics 2022-03-04 Daiwei Zhang , Lexin Li , Chandra Sripada , Jian Kang

Autism Spectrum Disorder (ASD) is a complex neurological condition characterized by varied developmental impairments, especially in communication and social interaction. Accurate and early diagnosis of ASD is crucial for effective…

Machine Learning · Computer Science 2025-03-18 Suchanuch Piriyasatit , Chaohao Yuan , Ercan Engin Kuruoglu

Technological advancements in noninvasive imaging facilitate the construction of whole brain interconnected networks, known as brain connectivity. Existing approaches to analyze brain connectivity frequently disaggregate the entire network…

Methodology · Statistics 2023-09-26 Xinyuan Tian , Fan Li , Li Shen , Denise Esserman , Yize Zhao

Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…

Machine Learning · Computer Science 2025-08-12 Yiran Huang , Amirhossein Nouranizadeh , Christine Ahrends , Mengjia Xu

Whole-brain network analyses remain the vanguard in neuroimaging research, coming to prominence within the last decade. Network science approaches have facilitated these analyses and allowed examining the brain as an integrated system.…

Applications · Statistics 2015-05-04 Sean L. Simpson , Paul J. Laurienti