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Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

Methodology · Statistics 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

The autism dataset is studied to identify the differences between autistic and healthy groups. For this, the resting-state Functional Magnetic Resonance Imaging (rs-fMRI) data of the two groups are analyzed, and networks of connections…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Ramchandra Rimal , Mitchell Brannon , Yingxin Wang , Xin Yang

Mixed membership models are a flexible class of probabilistic data representations used for unsupervised and semi-supervised learning, allowing each observation to partially belong to multiple clusters or features. In this manuscript, we…

Dynamic networks have been increasingly used to characterize brain connectivity that varies during resting and task states. In such characterizations, a connectivity network is typically measured at each time point for a subject over a…

Methodology · Statistics 2023-03-23 Maoyu Zhang , Biao Cai , Wenlin Dai , Dehan Kong , Hongyu Zhao , Jingfei Zhang

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition associated with difficulties with social interactions, communication, and restricted or repetitive behaviors. To characterize ASD, investigators often use functional…

Methodology · Statistics 2026-05-12 Jialu Ran , Sarah Shultz , Benjamin B. Risk , David Benkeser

Autism Spectrum Condition (ASC) is a neurodevelopmental condition characterized by impairments in communication, social interaction and restricted or repetitive behaviors. Extensive research has been conducted to identify distinctions…

Quantitative Methods · Quantitative Biology 2024-05-22 F. J. Alcaide , I. A. Illan , J. Ramirez , J. M. Gorriz

Whole-brain neural connectivity data are now available from viral tracing experiments, which reveal the connections between a source injection site and elsewhere in the brain. These hold the promise of revealing spatial patterns of…

Neurons and Cognition · Quantitative Biology 2016-10-27 Kameron Decker Harris , Stefan Mihalas , Eric Shea-Brown

This paper studies subtypes of restricted, repetitive and stereotypical behaviors (RRBs) in adolescent males with autism spectrum disorder (ASD) from the viewpoint of the dynamics of brain functional connectivities (FCs). Data from the…

Neurons and Cognition · Quantitative Biology 2025-04-23 Gerardo Noriega

Anatomical and functional brain studies have converged to the hypothesis that Autism Spectrum Disorders (ASD) are associated with atypical connectivity. Using a modified resting-state paradigm to drive subjects' attention, we provide…

Neurons and Cognition · Quantitative Biology 2012-11-21 Pablo Barttfeld , Bruno Wicker , Sebastián Cukier , Silvana Navarta , Sergio Lew , Ramón Leiguarda , Mariano Sigman

Autism spectrum disorder (ASD) has been associated with structural alterations across cortical and subcortical regions. Quantitative neuroimaging enables large-scale analysis of these neuroanatomical patterns. This project used structural…

Neurons and Cognition · Quantitative Biology 2025-12-30 Ashley Chen

In neuroimaging data analysis, Gaussian graphical models are often used to model statistical dependencies across spatially remote brain regions known as functional connectivity. Typically, data is collected across a cohort of subjects and…

Machine Learning · Statistics 2015-12-08 Ricardo Pio Monti , Christoforos Anagnostopoulos , Giovanni Montana

Recent applications of pattern recognition techniques on brain connectome classification using functional connectivity (FC) are shifting towards acknowledging the non-Euclidean topology and dynamic aspects of brain connectivity across time.…

Machine Learning · Computer Science 2024-11-12 Sin-Yee Yap , Junn Yong Loo , Chee-Ming Ting , Fuad Noman , Raphael C. -W. Phan , Adeel Razi , David L. Dowe

ABIDE is the largest open-source autism spectrum disorder database with both fMRI data and full phenotype description. These data were extensively studied based on functional connectivity analysis as well as with deep learning on raw data,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-15 Marina Pominova , Ekaterina Kondrateva , Maxim Sharaev , Alexander Bernstein , Evgeny Burnaev

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

Neurons and Cognition · Quantitative Biology 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

Functional brain connectivity, as revealed through distant correlations in the signals measured by functional Magnetic Resonance Imaging (fMRI), is a promising source of biomarkers of brain pathologies. However, establishing and using…

This paper presents a streamlined image analysis framework for correlating behavioral measures to anatomical measures on the cortex and detecting the regions of abnormal brain-behavior correlates. We correlated a facial emotion…

Neurons and Cognition · Quantitative Biology 2025-07-02 Moo K. Chung , Kim M. Dalton , Daniel J. Kelley , Richard J. Davidson

Voxel-based analysis methods localize brain structural differences by performing voxel-wise statistical comparisons on two groups of images aligned to a common space. This procedure requires highly accurate registration as well as a…

Spontaneous brain activity, as observed in functional neuroimaging, has been shown to display reproducible structure that expresses brain architecture and carries markers of brain pathologies. An important view of modern neuroscience is…

Machine Learning · Statistics 2010-11-15 Gaël Varoquaux , Alexandre Gramfort , Jean Baptiste Poline , Bertrand Thirion

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by atypical brain connectivity. One of the crucial steps in addressing ASD is its early detection. This study introduces a novel computational framework that…

Applications · Statistics 2026-03-31 Abigail Kelly , Ramchandra Rimal , Arpan Sainju

Autism spectrum disorder is one of the leading neurodevelopmental disorders in our world, present in over 1% of the population and rapidly increasing in prevalence, yet the condition lacks a robust, objective, and efficient diagnostic.…

Neurons and Cognition · Quantitative Biology 2024-03-04 Annie Adhikary