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We introduce an explainability method for biomedical hypothesis generation systems, built on top of the novel Hypothesis Generation Context Retriever framework. Our approach combines semantic graph-based retrieval and relevant…

Autonomous Driving Systems (ADS) use complex decision-making (DM) models with multimodal sensory inputs, making rigorous validation and verification (V&V) essential for safety and reliability. These models pose challenges in diagnosing…

Agent-based simulation is crucial for modeling complex human behavior, yet traditional approaches require extensive domain knowledge and large datasets. In data-scarce healthcare settings where historic and counterfactual data are limited,…

Medical large language models (LLMs) achieve impressive performance on standardized benchmarks, yet these evaluations fail to capture the complexity of real clinical encounters where patients exhibit memory gaps, limited health literacy,…

This paper explores the potential of using Large Language Models (LLMs) to automate the evaluation of responses in medical Question and Answer (Q\&A) systems, a crucial form of Natural Language Processing. Traditionally, human evaluation…

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of…

Machine reasoning has made great progress in recent years owing to large language models (LLMs). In the clinical domain, however, most NLP-driven projects mainly focus on clinical classification or reading comprehension, and under-explore…

Large language models (LLMs) have the potential to aid and improve human decision-making in classification tasks, not only by providing fairly accurate predictions, but also in their ability to generate cogent narrative explanations of…

Large language models (LLMs) show promise for supporting clinicians in diagnostic communication by generating explanations and guidance for patients. Yet their ability to produce outputs that are both understandable and empathetic remains…

Leveraging outputs from multiple large language models (LLMs) is emerging as a method for harnessing their power across a wide range of tasks while mitigating their capacity for making errors, e.g., hallucinations. However, current…

Resolving ambiguities through interaction is a hallmark of natural language, and modeling this behavior is a core challenge in crafting AI assistants. In this work, we study such behavior in LMs by proposing a task-agnostic framework for…

Clinical trial matching is the task of identifying trials for which patients may be potentially eligible. Typically, this task is labor-intensive and requires detailed verification of patient electronic health records (EHRs) against the…

The breakthrough of OpenAI o1 highlights the potential of enhancing reasoning to improve LLM. Yet, most research in reasoning has focused on mathematical tasks, leaving domains like medicine underexplored. The medical domain, though…

Large Language Models (LLMs) have emerged as transformative tools in the healthcare sector, demonstrating remarkable capabilities in natural language understanding and generation. However, their proficiency in numerical reasoning,…

As large language models (LLMs) are increasingly deployed in sensitive domains such as healthcare, law, and education, the demand for transparent, interpretable, and accountable AI systems becomes more urgent. Explainable AI (XAI) acts as a…

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Recent research has shown that hallucinations, omissions, and biases are prevalent in everyday use-cases of LLMs. However, chatbots used in medical contexts must provide consistent advice in situations where non-medical factors are…

Artificial intelligence (AI) is transforming the practice of science. Machine learning and large language models (LLMs) can generate hypotheses at a scale and speed far exceeding traditional methods, offering the potential to accelerate…

Biomedical question answering (QA) requires accurate interpretation of complex medical knowledge. Large language models (LLMs) have shown promising capabilities in this domain, with retrieval-augmented generation (RAG) systems enhancing…