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Recent advancements in AI applications to healthcare have shown incredible promise in surpassing human performance in diagnosis and disease prognosis. With the increasing complexity of AI models, however, concerns regarding their opacity,…

Machine Learning · Computer Science 2023-08-17 Munib Mesinovic , Peter Watkinson , Tingting Zhu

The challenge of creating interpretable models has been taken up by two main research communities: ML researchers primarily focused on lower-level explainability methods that suit the needs of engineers, and HCI researchers who have more…

Machine Learning · Computer Science 2024-07-16 Juan D. Pinto , Luc Paquette

The need for interpretable and accountable intelligent systems grows along with the prevalence of artificial intelligence applications used in everyday life. Explainable intelligent systems are designed to self-explain the reasoning behind…

Human-Computer Interaction · Computer Science 2020-08-06 Sina Mohseni , Niloofar Zarei , Eric D. Ragan

Transformer-based models have become state-of-the-art tools in various machine learning tasks, including time series classification, yet their complexity makes understanding their internal decision-making challenging. Existing…

Machine Learning · Computer Science 2025-11-27 Matīss Kalnāre , Sofoklis Kitharidis , Thomas Bäck , Niki van Stein

A wide variety of model explanation approaches have been proposed in recent years, all guided by very different rationales and heuristics. In this paper, we take a new route and cast interpretability as a statistical inference problem. We…

Machine Learning · Computer Science 2024-01-01 Hugo Henri Joseph Senetaire , Damien Garreau , Jes Frellsen , Pierre-Alexandre Mattei

Interpretable machine learning models offer understandable reasoning behind their decision-making process, though they may not always match the performance of their black-box counterparts. This trade-off between interpretability and model…

Artificial Intelligence · Computer Science 2025-03-12 Pranjal Atrey , Michael P. Brundage , Min Wu , Sanghamitra Dutta

Selective rationalization improves neural network interpretability by identifying a small subset of input features -- the rationale -- that best explains or supports the prediction. A typical rationalization criterion, i.e. maximum mutual…

Machine Learning · Computer Science 2020-03-24 Shiyu Chang , Yang Zhang , Mo Yu , Tommi S. Jaakkola

Machines are being increasingly used in decision-making processes, resulting in the realization that decisions need explanations. Unfortunately, an increasing number of these deployed models are of a 'black-box' nature where the reasoning…

Artificial Intelligence · Computer Science 2023-11-07 Sopam Dasgupta

Artificial Intelligence (AI) has become an integral part of domains such as security, finance, healthcare, medicine, and criminal justice. Explaining the decisions of AI systems in human terms is a key challenge--due to the high complexity…

Artificial Intelligence · Computer Science 2019-11-25 Sheikh Rabiul Islam , William Eberle , Sheikh K. Ghafoor

The use of wearables in medicine and wellness, enabled by AI-based models, offers tremendous potential for real-time monitoring and interpretable event detection. Explainable AI (XAI) is required to assess what models have learned and build…

Signal Processing · Electrical Eng. & Systems 2026-03-16 Maurice Kuschel , Solveig Vieluf , Claus Reinsberger , Tobias Loddenkemper , Tanuj Hasija

Interpretability for machine learning models in medical imaging (MLMI) is an important direction of research. However, there is a general sense of murkiness in what interpretability means. Why does the need for interpretability in MLMI…

Machine Learning · Computer Science 2024-04-17 Alan Q. Wang , Batuhan K. Karaman , Heejong Kim , Jacob Rosenthal , Rachit Saluja , Sean I. Young , Mert R. Sabuncu

Interpretability methods are valuable only if their explanations faithfully describe the explained model. In this work, we consider neural networks whose predictions are invariant under a specific symmetry group. This includes popular…

Machine Learning · Computer Science 2023-10-06 Jonathan Crabbé , Mihaela van der Schaar

Mechanistic interpretability papers increasingly use causal vocabulary: circuits, mediators, causal abstraction, monosemanticity. Such claims require explicit identification assumptions. A purposive audit of 10 papers across four…

Machine Learning · Computer Science 2026-05-11 Zezheng Lin , Fengming Liu

The lack of interpretability has hindered the large-scale adoption of AI technologies. However, the fundamental idea of interpretability, as well as how to put it into practice, remains unclear. We provide notions of interpretability based…

Machine Learning · Computer Science 2021-11-18 Hangcheng Dong , Bingguo Liu , Fengdong Chen , Dong Ye , Guodong Liu

Interpretability is a pressing issue for machine learning. Common approaches to interpretable machine learning constrain interactions between features of the input, rendering the effects of those features on a model's output comprehensible…

Machine Learning · Computer Science 2023-05-11 Kieran A. Murphy , Dani S. Bassett

In a striking neuroscience study, the authors placed a dead salmon in an MRI scanner and showed it images of humans in social situations. Astonishingly, standard analyses of the time reported brain regions predictive of social emotions. The…

Artificial Intelligence · Computer Science 2025-12-23 Maxime Méloux , Giada Dirupo , François Portet , Maxime Peyrard

Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

Machine Learning · Computer Science 2018-06-27 Anirban Mukhopadhyay

Deep learning continues to revolutionize an ever-growing number of critical application areas including healthcare, transportation, finance, and basic sciences. Despite their increased predictive power, model transparency and human…

Machine Learning · Computer Science 2020-04-28 Benjamin Shickel , Parisa Rashidi

Mechanistic interpretability aims to understand the internal mechanisms learned by neural networks. Despite recent progress toward this goal, it remains unclear how best to decompose neural network parameters into mechanistic components. We…

Machine Learning · Computer Science 2025-02-11 Dan Braun , Lucius Bushnaq , Stefan Heimersheim , Jake Mendel , Lee Sharkey

We argue that existing definitions of interpretability are not actionable in that they fail to inform users about general, sound, and robust interpretable model design. This makes current interpretability research fundamentally ill-posed.…

Machine Learning · Computer Science 2025-08-04 Pietro Barbiero , Mateo Espinosa Zarlenga , Alberto Termine , Mateja Jamnik , Giuseppe Marra
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