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Deep learning based automated pathological diagnosis has markedly improved diagnostic efficiency and reduced variability between observers, yet its clinical adoption remains limited by opaque model decisions and a lack of traceable…

Pathology image segmentation is crucial in computational pathology for analyzing histological features relevant to cancer diagnosis and prognosis. However, current methods face major challenges in clinical applications due to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zhixuan Chen , Junlin Hou , Liqi Lin , Yihui Wang , Yequan Bie , Xi Wang , Yanning Zhou , Ronald Cheong Kin Chan , Hao Chen

Recent advances in deep learning have completely transformed the domain of computational pathology (CPath). More specifically, it has altered the diagnostic workflow of pathologists by integrating foundation models (FMs) and vision-language…

Machine Learning · Computer Science 2024-09-19 Dibaloke Chanda , Milan Aryal , Nasim Yahya Soltani , Masoud Ganji

Although Vision Language Models (VLMs) have shown strong generalization in medical imaging, pathology presents unique challenges due to ultra-high resolution, complex tissue structures, and nuanced clinical semantics. These factors make…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Wenchuan Zhang , Jingru Guo , Hengzhe Zhang , Penghao Zhang , Jie Chen , Shuwan Zhang , Zhang Zhang , Yuhao Yi , Hong Bu

Visual grounding (VG) is the capability to identify the specific regions in an image associated with a particular text description. In medical imaging, VG enhances interpretability by highlighting relevant pathological features…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Ta Duc Huy , Duy Anh Huynh , Yutong Xie , Yuankai Qi , Qi Chen , Phi Le Nguyen , Sen Kim Tran , Son Lam Phung , Anton van den Hengel , Zhibin Liao , Minh-Son To , Johan W. Verjans , Vu Minh Hieu Phan

Visual grounding (VG) aims to establish fine-grained alignment between vision and language. Ideally, it can be a testbed for vision-and-language models to evaluate their understanding of the images and texts and their reasoning abilities…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Zhihong Chen , Ruifei Zhang , Yibing Song , Xiang Wan , Guanbin Li

Visual grounding aims to align visual information of specific regions of images with corresponding natural language expressions. Current visual grounding methods leverage pre-trained visual and language backbones independently to obtain…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Jiaxi Wang , Wenhui Hu , Xueyang Liu , Beihu Wu , Yuting Qiu , YingYing Cai

Accurate analysis of pathological images is essential for automated tumor diagnosis but remains challenging due to high structural similarity and subtle morphological variations in tissue images. Current vision-language (VL) models often…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Yating Huang , Ziyan Huang , Lintao Xiang , Qijun Yang , Hujun Yin

The diagnosis of pathological images is often limited by expert availability and regional disparities, highlighting the importance of automated diagnosis using Vision-Language Models (VLMs). Traditional multimodal models typically emphasize…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Jianyu Wu , Hao Yang , Xinhua Zeng , Guibing He , Zhiyu Chen , Zihui Li , Xiaochuan Zhang , Yangyang Ma , Run Fang , Yang Liu

Vision-Language Models (VLMs) offer significant potential in computational pathology by enabling interpretable image analysis, automated reporting, and scalable decision support. However, their widespread clinical adoption remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Minbing Chen , Zhu Meng , Fei Su

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Vision-Language Models (VLMs) can generate convincing clinical narratives, yet frequently struggle to visually ground their statements. We posit this limitation arises from the scarcity of high-quality, large-scale clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Mengmeng Zhang , Xiaoping Wu , Hao Luo , Fan Wang , Yisheng Lv

In this paper, we consider the problem of visual representation learning for computational pathology, by exploiting large-scale image-text pairs gathered from public resources, along with the domain-specific knowledge in pathology.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Xiao Zhou , Xiaoman Zhang , Chaoyi Wu , Ya Zhang , Weidi Xie , Yanfeng Wang

Foundation models and vision-language pre-training have significantly advanced Vision-Language Models (VLMs), enabling multimodal processing of visual and linguistic data. However, their application in domain-specific agricultural tasks,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Khang Nguyen Quoc , Phuong D. Dao , Luyl-Da Quach

Pathology image segmentation across multiple centers encounters significant challenges due to diverse sources of heterogeneity including imaging modalities, organs, and scanning equipment, whose variability brings representation bias and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-29 Yuan Zhang , Feng Chen , Yaolei Qi , Guanyu Yang , Huazhu Fu

The field of computational pathology has witnessed remarkable progress in the development of both task-specific predictive models and task-agnostic self-supervised vision encoders. However, despite the explosive growth of generative…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Ming Y. Lu , Bowen Chen , Drew F. K. Williamson , Richard J. Chen , Kenji Ikamura , Georg Gerber , Ivy Liang , Long Phi Le , Tong Ding , Anil V Parwani , Faisal Mahmood

The emergence of pathology foundation models has revolutionized computational histopathology, enabling highly accurate, generalized whole-slide image analysis for improved cancer diagnosis, and prognosis assessment. While these models show…

The emergence of large multimodal models has unlocked remarkable potential in AI, particularly in pathology. However, the lack of specialized, high-quality benchmark impeded their development and precise evaluation. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yuxuan Sun , Hao Wu , Chenglu Zhu , Sunyi Zheng , Qizi Chen , Kai Zhang , Yunlong Zhang , Dan Wan , Xiaoxiao Lan , Mengyue Zheng , Jingxiong Li , Xinheng Lyu , Tao Lin , Lin Yang

Accurate diagnosis and prognosis assisted by pathology images are essential for cancer treatment selection and planning. Despite the recent trend of adopting deep-learning approaches for analyzing complex pathology images, they fall short…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Awais Naeem , Tianhao Li , Huang-Ru Liao , Jiawei Xu , Aby M. Mathew , Zehao Zhu , Zhen Tan , Ajay Kumar Jaiswal , Raffi A. Salibian , Ziniu Hu , Tianlong Chen , Ying Ding

Visual grounding, the task of localizing objects described by natural-language expressions, is a foundational capability for agricultural AI systems, enabling applications such as selective weeding, disease monitoring, and targeted…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Haocheng Li , Juepeng Zheng , Zenghao Yang , Kaiqi Du , Guilong Xiao , Gengmeng Pu , Haohuan Fu , Jianxi Huang
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