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The transmission dynamics of an epidemic are rarely homogeneous. Super-spreading events and super-spreading individuals are two types of heterogeneous transmissibility. Inference of super-spreading is commonly carried out on secondary case…

Quantitative Methods · Quantitative Biology 2025-01-23 Hannah Craddock , Simon EF Spencer , Xavier Didelot

Human behavior plays a critical role in shaping epidemic trajectories. During health crises, people respond in diverse ways in terms of self-protection and adherence to recommended measures, largely reflecting differences in how individuals…

Physics and Society · Physics 2026-01-30 Fabio Mazza , Gabriele Ricci , Francesca Colaiori , Stefano Guarino , Sandro Meloni , Fabio Saracco

Nowcasting and forecasting of epidemic spreading rely on incidence series of reported cases to derive the fundamental epidemiological parameters for a given pathogen. Two relevant drawbacks for predictions are the unknown fractions of…

Populations and Evolution · Quantitative Biology 2022-08-31 Guilherme S. Costa , Wesley Cota , Silvio C. Ferreira

Accurate estimates of the reproduction ratio are crucial to project infectious disease epidemic evolution and guide public health response. Here, we prove that estimates of the reproduction ratio based on inference from surveillance data…

Physics and Society · Physics 2025-01-08 Piero Birello , Michele Re Fiorentin , Boxuan Wang , Vittoria Colizza , Eugenio Valdano

Epidemic spreading of infectious diseases is ubiquitous and has often considerable impact on public health and economic wealth. The large variability in spatio-temporal patterns of epidemics prohibits simple interventions and demands for a…

Populations and Evolution · Quantitative Biology 2010-11-25 Christel Kamp

We explore how heterogeneity in the intensity of interactions between people affects epidemic spreading. For that, we study the susceptible-infected-susceptible model on a complex network, where a link connecting individuals $i$ and $j$ is…

Physics and Society · Physics 2013-08-28 C. Buono , F. Vazquez , P. A. Macri , L. A. Braunstein

We propose a new paradigm to design a network-based self-adaptive epidemic model that relies on the interplay between the network and its line graph. We implement this proposal on a Susceptible-Infected-Susceptible model in which both nodes…

Adaptation and Self-Organizing Systems · Physics 2024-03-05 Paolo Bartesaghi , Gian Paolo Clemente , Rosanna Grassi

The course of an epidemic is not only shaped by infection transmission over face-to-face contacts, but also by preventive behaviour caused by risk perception and social interactions. This study explores the dynamics of coupled awareness and…

Physics and Society · Physics 2025-02-24 Tim Van Wesemael , Luis E. C. Rocha , Jan M. Baetens

During an epidemic outbreak, decision makers crucially need accurate and robust tools to monitor the pathogen propagation. The effective reproduction number, defined as the expected number of secondary infections stemming from one…

Signal Processing · Electrical Eng. & Systems 2026-01-14 Etienne Lasalle , Barbara Pascal

Eigenvector centrality is an established measure of global connectivity, from which the importance and influence of nodes can be inferred. We introduce a local eigenvector centrality that incorporates both local and global connectivity.…

Social and Information Networks · Computer Science 2025-11-19 Ruaridh A. Clark , Francesca Arrigo , Agathe Bouis , Malcolm Macdonald

The epidemic threshold of a spreading process indicates the condition for the occurrence of the wide spreading regime, thus representing a predictor of the network vulnerability to the epidemic. Such threshold depends on the natural history…

Physics and Society · Physics 2016-01-20 Eugenio Valdano , Chiara Poletto , Vittoria Colizza

Mathematical modeling of disease spreading plays a crucial role in understanding, controlling and preventing epidemic outbreaks. In a microscopic description of the propagation of a disease over the complex network of human contacts, the…

Physics and Society · Physics 2021-10-08 Federico Malizia , Luca Gallo , Mattia Frasca , Vito Latora , Giovanni Russo

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

Classical compartmental models in epidemiology often assume a homogeneous population for simplicity, which neglects the inherent heterogeneity among individuals. This assumption frequently leads to inaccurate predictions when applied to…

Populations and Evolution · Quantitative Biology 2024-09-09 Ning Jiang , Weiqi Chu , Yao Li

It has recently become established that the spread of infectious diseases between humans is affected not only by the pathogen itself but also by changes in behavior as the population becomes aware of the epidemic; for example, social…

Physics and Society · Physics 2013-10-09 Yilei Bu , Steve Gregory , Harriet L. Mills

We consider a flexible Bayesian evidence synthesis approach to model the age-specific transmission dynamics of COVID-19 based on daily mortality counts. The temporal evolution of transmission rates in populations containing multiple types…

Edge-based percolation methods can be used to analyze disease transmission on complex social networks. This allows us to include complex social heterogeneity in our models while maintaining tractability. Here we review the seminal works on…

Social and Information Networks · Computer Science 2025-04-17 S. Zhao , F. M. G. Magpantay

We study a class of individual-based, fixed-population size epidemic models under general assumptions, e.g., heterogeneous contact rates encapsulating changes in behavior and/or enforcement of control measures. We show that the…

Probability · Mathematics 2023-07-04 Jean-Jil Duchamps , Félix Foutel-Rodier , Emmanuel Schertzer

Network-based epidemic models have been extensively employed to understand the spread of infectious diseases, but have generally overlooked the fact that most realistic networks are dynamical rather than static. In this paper, we study a…

Physics and Society · Physics 2019-02-19 Xiao-Long Peng , Ze-Qiong Zhang , Junyuan Yang , Zhen Jin

Epidemic control is of great importance for human society. Adjusting interacting partners is an effective individualized control strategy. Intuitively, it is done either by shortening the interaction time between susceptible and infected…

Populations and Evolution · Quantitative Biology 2016-12-28 Bin Wu , Shanjun Mao , Jiazeng Wang , Da Zhou