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Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Large Language Model (LLM)-enhanced agents become increasingly prevalent in Human-AI communication, offering vast potential from entertainment to professional domains. However, current multi-modal dialogue systems overlook the acoustic…

Computation and Language · Computer Science 2024-06-19 Haoqiu Yan , Yongxin Zhu , Kai Zheng , Bing Liu , Haoyu Cao , Deqiang Jiang , Linli Xu

While Multimodal Large Language Models (MLLMs) show immense promise for achieving truly human-like interactions, progress is hindered by the lack of fine-grained evaluation frameworks for human-centered scenarios, encompassing both the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Zheng Qin , Ruobing Zheng , Yabing Wang , Tianqi Li , Yi Yuan , Jingdong Chen , Le Wang

The rapid advancements in large language models (LLMs) have opened up new opportunities for transforming patient engagement in healthcare through conversational AI. This paper presents an overview of the current landscape of LLMs in…

Artificial Intelligence · Computer Science 2024-11-27 Bo Wen , Raquel Norel , Julia Liu , Thaddeus Stappenbeck , Farhana Zulkernine , Huamin Chen

Recent advancements in large language models (LLMs) have shown promise in generating psychotherapeutic dialogues, particularly in the context of motivational interviewing (MI). However, the inherent lack of transparency in LLM outputs…

Computation and Language · Computer Science 2024-12-18 Xin Sun , Xiao Tang , Abdallah El Ali , Zhuying Li , Pengjie Ren , Jan de Wit , Jiahuan Pei , Jos A. Bosch

Human communication is a complex and diverse process that not only involves multiple factors such as language, commonsense, and cultural backgrounds but also requires the participation of multimodal information, such as speech. Large…

Computation and Language · Computer Science 2024-01-09 Dong Zhang , Zhaowei Li , Pengyu Wang , Xin Zhang , Yaqian Zhou , Xipeng Qiu

We propose a multi-agent framework for modeling artificial consciousness in large language models (LLMs), grounded in psychoanalytic theory. Our \textbf{Psychodynamic Model} simulates self-awareness, preconsciousness, and unconsciousness…

Computation and Language · Computer Science 2025-10-22 Sang Hun Kim , Jongmin Lee , Dongkyu Park , So Young Lee , Yosep Chong

We present Tell Me, a mental well-being system that leverages advances in large language models to provide accessible, context-aware support for users and researchers. The system integrates three components: (i) a retrieval-augmented…

Computation and Language · Computer Science 2025-11-19 Trishala Jayesh Ahalpara

Human conversation involves language, speech, and visual cues, with each medium providing complementary information. For instance, speech conveys a vibe or tone not fully captured by text alone. While multimodal LLMs focus on generating…

Human-Computer Interaction · Computer Science 2025-09-19 Taesoo Kim , Yongsik Jo , Hyunmin Song , Taehwan Kim

Therapeutic art activities, such as expressive drawing and painting, require the synergy between creative visual production and interactive dialogue. Recent advancements in Multimodal Large Language Models (MLLMs) have expanded the capacity…

Human-Computer Interaction · Computer Science 2026-05-12 Le Lin , Zihao Zhu , Rainbow Tin Hung Ho , Jing Liao , Yuhan Luo

This study investigates the efficacy of Large Language Models (LLMs) in interactive language therapy for high-functioning autistic adolescents. With the rapid advancement of artificial intelligence, particularly in natural language…

Human-Computer Interaction · Computer Science 2023-11-17 Yujin Cho , Mingeon Kim , Seojin Kim , Oyun Kwon , Ryan Donghan Kwon , Yoonha Lee , Dohyun Lim

Human cognition is constrained by processing limitations, leading to cognitive overload and inefficiencies in knowledge synthesis and decision-making. Large Language Models (LLMs) present an opportunity for cognitive augmentation, but their…

Human-Computer Interaction · Computer Science 2025-04-21 Xiangrong , Zhu , Yuan Xu , Tianjian Liu , Jingwei Sun , Yu Zhang , Xin Tong

This paper explores enhancing empathy in Large Language Models (LLMs) by integrating them with physiological data. We propose a physiological computing approach that includes developing deep learning models that use physiological data for…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Poorvesh Dongre , Majid Behravan , Kunal Gupta , Mark Billinghurst , Denis Gračanin

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

With the advancement of large language models, many dialogue systems are now capable of providing reasonable and informative responses to patients' medical conditions. However, when patients consult their doctor, they may experience…

Computation and Language · Computer Science 2025-06-17 Shang-Chi Tsai , Yun-Nung Chen

Empathy is central to human connection, yet people often struggle to express it effectively. In blinded evaluations, large language models (LLMs) generate responses that are often judged more empathic than human-written ones. Yet when a…

Computation and Language · Computer Science 2026-03-17 Aakriti Kumar , Nalin Poungpeth , Diyi Yang , Bruce Lambert , Matthew Groh

People experiencing severe distress increasingly use Large Language Model (LLM) chatbots as mental health support tools. Discussions on social media have described how engagements were lifesaving for some, but evidence suggests that…

Human-Computer Interaction · Computer Science 2025-05-12 Inhwa Song , Sachin R. Pendse , Neha Kumar , Munmun De Choudhury

We present Empathic Prompting, a novel framework for multimodal human-AI interaction that enriches Large Language Model (LLM) conversations with implicit non-verbal context. The system integrates a commercial facial expression recognition…

Human-Computer Interaction · Computer Science 2026-05-29 Lorenzo Stacchio , Andrea Ubaldi , Alessandro Galdelli , Maurizio Mauri , Emanuele Frontoni , Andrea Gaggioli

Recent progress in large language models (LLMs) has opened new possibilities for mental health support, yet current approaches lack realism in simulating specialized psychotherapy and fail to capture therapeutic progression over time.…

Computation and Language · Computer Science 2025-09-15 Yi Feng , Jiaqi Wang , Wenxuan Zhang , Zhuang Chen , Yutong Shen , Xiyao Xiao , Minlie Huang , Liping Jing , Jian Yu

Large language models (LLMs) have rapidly shifted from peripheral assistive tools to constant companions in everyday and even high stakes human decision making. Many users now consult these models about health, intimate relationships,…

Computers and Society · Computer Science 2026-02-26 Abas Bertina , Sara Shakeri