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Related papers: OntologyRAG: Better and Faster Biomedical Code Map…

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Large language models (LLMs) are rapidly transforming various domains, including biomedicine and healthcare, and demonstrate remarkable potential from scientific research to new drug discovery. Graph-based retrieval-augmented generation…

Quantitative Methods · Quantitative Biology 2025-11-14 Guofeng Meng , Li Shen , Qiuyan Zhong , Wei Wang , Haizhou Zhang , Xiaozhen Wang

Large language models (LLMs) are transforming the way information is retrieved with vast amounts of knowledge being summarized and presented via natural language conversations. Yet, LLMs are prone to highlight the most frequently seen…

Computation and Language · Computer Science 2024-02-20 Julien Delile , Srayanta Mukherjee , Anton Van Pamel , Leonid Zhukov

This paper presents OG-RAG, an Ontology-Grounded Retrieval Augmented Generation method designed to enhance LLM-generated responses by anchoring retrieval processes in domain-specific ontologies. While LLMs are widely used for tasks like…

Computation and Language · Computer Science 2024-12-23 Kartik Sharma , Peeyush Kumar , Yunqing Li

Ontologies are pivotal for structuring knowledge bases to enhance question answering (QA) systems powered by Large Language Models (LLMs). However, traditional ontology creation relies on manual efforts by domain experts, a process that is…

Artificial Intelligence · Computer Science 2025-06-03 Yash Tiwari , Owais Ahmad Lone , Mayukha Pal

We introduce a novel graph-based Retrieval-Augmented Generation (RAG) framework specifically designed for the medical domain, called \textbf{MedGraphRAG}, aimed at enhancing Large Language Model (LLM) capabilities for generating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-17 Junde Wu , Jiayuan Zhu , Yunli Qi , Jingkun Chen , Min Xu , Filippo Menolascina , Vicente Grau

Large language models (LLMs) have recently become the leading source of answers for users' questions online. Despite their ability to offer eloquent answers, their accuracy and reliability can pose a significant challenge. This is…

Computation and Language · Computer Science 2024-07-09 Bojana Bašaragin , Adela Ljajić , Darija Medvecki , Lorenzo Cassano , Miloš Košprdić , Nikola Milošević

Large Language Models (LLMs) have swiftly emerged as vital resources for different applications in the biomedical and healthcare domains; however, these models encounter issues such as generating inaccurate information or hallucinations.…

Computation and Language · Computer Science 2024-05-06 Mingchen Li , Halil Kilicoglu , Hua Xu , Rui Zhang

Large Language Models (LLMs) are being adopted at an unprecedented rate, yet still face challenges in knowledge-intensive domains like biomedicine. Solutions such as pre-training and domain-specific fine-tuning add substantial computational…

Large language models (LLMs) offer new opportunities for constructing knowledge graphs (KGs) from unstructured clinical narratives. However, existing approaches often rely on structured inputs and lack robust validation of factual accuracy…

Artificial Intelligence · Computer Science 2026-01-06 Udiptaman Das , Krishnasai B. Atmakuri , Duy Ho , Chi Lee , Yugyung Lee

Large language models (LLMs) have demonstrated remarkable capabilities in a wide range of tasks, yet their application to specialized domains remains challenging due to the need for deep expertise. Retrieval-Augmented generation (RAG) has…

Computation and Language · Computer Science 2025-09-30 Qinggang Zhang , Shengyuan Chen , Yuanchen Bei , Zheng Yuan , Huachi Zhou , Zijin Hong , Hao Chen , Yilin Xiao , Chuang Zhou , Junnan Dong , Yi Chang , Xiao Huang

Recent proprietary large language models (LLMs), such as GPT-4, have achieved a milestone in tackling diverse challenges in the biomedical domain, ranging from multiple-choice questions to long-form generations. To address challenges that…

Computation and Language · Computer Science 2024-06-19 Minbyul Jeong , Jiwoong Sohn , Mujeen Sung , Jaewoo Kang

Retrieval-Augmented Generation (RAG) systems combine Large Language Models (LLMs) with external knowledge, and their performance depends heavily on how that knowledge is represented. This study investigates how different Knowledge Graph…

Information Retrieval · Computer Science 2025-11-11 Tiago da Cruz , Bernardo Tavares , Francisco Belo

Extracting relevant and structured knowledge from large, complex technical documents within the Reliability and Maintainability (RAM) domain is labor-intensive and prone to errors. Our work addresses this challenge by presenting OntoKGen, a…

Artificial Intelligence · Computer Science 2024-12-11 Mohammad Sadeq Abolhasani , Rong Pan

Competency question (CQ) formulation is central to several ontology development and evaluation methodologies. Traditionally, the task of crafting these competency questions heavily relies on the effort of domain experts and knowledge…

Artificial Intelligence · Computer Science 2025-02-13 Xueli Pan , Jacco van Ossenbruggen , Victor de Boer , Zhisheng Huang

Ontology Matching (OM) is a cornerstone task of semantic interoperability, yet existing systems often rely on handcrafted rules or specialized models with limited adaptability. We present KROMA, a novel OM framework that harnesses Large…

Artificial Intelligence · Computer Science 2025-09-12 Lam Nguyen , Erika Barcelos , Roger French , Yinghui Wu

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

The question-answering system for Life science research, which is characterized by the rapid pace of discovery, evolving insights, and complex interactions among knowledge entities, presents unique challenges in maintaining a comprehensive…

Computation and Language · Computer Science 2024-08-15 Chengrui Wang , Qingqing Long , Meng Xiao , Xunxin Cai , Chengjun Wu , Zhen Meng , Xuezhi Wang , Yuanchun Zhou

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

Large language models (LLMs) frequently generate confident yet factually incorrect content when used for language generation (a phenomenon often known as hallucination). Retrieval augmented generation (RAG) tries to reduce factual errors by…

Information Retrieval · Computer Science 2026-04-01 Dobrik Georgiev , Kheeran Naidu , Alberto Cattaneo , Federico Monti , Carlo Luschi , Daniel Justus

Retrieval-Augmented Generation (RAG) improves large language models (LLMs) by retrieving relevant information from external sources and has been widely adopted for text-based tasks. For structured data, such as knowledge graphs, Graph…

Information Retrieval · Computer Science 2026-03-05 Haoyu Han , Li Ma , Yu Wang , Harry Shomer , Yongjia Lei , Zhisheng Qi , Kai Guo , Zhigang Hua , Bo Long , Hui Liu , Charu C. Aggarwal , Jiliang Tang
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