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Brain network topology, derived from functional magnetic resonance imaging (fMRI), holds promise for improving Alzheimer's disease (AD) diagnosis. Current methods primarily focus on lower-order topological features, often overlooking the…

Geometric Topology · Mathematics 2025-09-19 Dengyi Zhao , Shanyong Li , Yunping Wang , Chenfei Wang , Zhiheng Zhou , Guiying Yan , Xingqin Qi

Chronological age of healthy brain is able to be predicted using deep neural networks from T1-weighted magnetic resonance images (T1 MRIs), and the predicted brain age could serve as an effective biomarker for detecting aging-related…

Computer Vision and Pattern Recognition · Computer Science 2022-05-12 Yu Fu , Yanyan Huang , Yalin Wang , Shunjie Dong , Le Xue , Xunzhao Yin , Qianqian Yang , Yiyu Shi , Cheng Zhuo

Functional MRI is a neuroimaging technique that analyzes the functional activity of the brain by measuring blood-oxygen-level-dependent signals throughout the brain. The derived functional features can be used for investigating brain…

Neurons and Cognition · Quantitative Biology 2026-02-16 Giorgio Dolci , Silvia Saglia , Lorenza Brusini , Vince D. Calhoun , Ilaria Boscolo Galazzo , Gloria Menegaz

Neuropsychiatric disorders impact functional connectivity of the brain at the network level. The identification and statistical testing of disorder-related networks remains challenging. We propose novel methods to streamline the detection…

Applications · Statistics 2017-01-16 Shuo Chen , Yishi Xing , Jian Kang , Dinesh Shukla , Peter Kochunov , L. Elliot Hong

Functional brain dynamics is supported by parallel and overlapping functional network modes that are associated with specific neural circuits. Decomposing these network modes from fMRI data and finding their temporal characteristics is…

Artificial Intelligence · Computer Science 2023-12-08 Md Asadullah Turja , Martin Styner , Guorong Wu

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

A novel unsupervised deep learning method is developed to identify individual-specific large scale brain functional networks (FNs) from resting-state fMRI (rsfMRI) in an end-to-end learning fashion. Our method leverages deep Encoder-Decoder…

Computer Vision and Pattern Recognition · Computer Science 2020-12-14 Hongming Li , Yong Fan

We present a deep semi-nonnegative matrix factorization method for identifying subject-specific functional networks (FNs) at multiple spatial scales with a hierarchical organization from resting state fMRI data. Our method is built upon a…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Hongming Li , Xiaofeng Zhu , Yong Fan

Cognitive neuroscience is enjoying rapid increase in extensive public brain-imaging datasets. It opens the door to large-scale statistical models. Finding a unified perspective for all available data calls for scalable and automated…

Machine Learning · Statistics 2019-05-16 Arthur Mensch , Julien Mairal , Danilo Bzdok , Bertrand Thirion , Gaël Varoquaux

Identifying unusual brain activity is a crucial task in neuroscience research, as it aids in the early detection of brain disorders. It is common to represent brain networks as graphs, and researchers have developed various graph-based…

Machine Learning · Computer Science 2024-10-04 Sadaf Sadeghian , Xiaoxiao Li , Margo Seltzer

Functional magnetic resonance imaging (fMRI) is a powerful tool for probing brain function, yet reliable clinical diagnosis is hampered by low signal-to-noise ratios, inter-subject variability, and the limited frequency awareness of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Junhao Jia , Yifei Sun , Yunyou Liu , Cheng Yang , Changmiao Wang , Feiwei Qin , Yong Peng , Wenwen Min

In the last decade, network science has shed new light both on the structural (anatomical) and on the functional (correlations in the activity) connectivity among the different areas of the human brain. The analysis of brain networks has…

Physics and Society · Physics 2017-04-18 Federico Battiston , Vincenzo Nicosia , Mario Chavez , Vito Latora

The integration of multi-modal Magnetic Resonance Imaging (MRI) and clinical data holds great promise for enhancing the diagnosis of neurological disorders (NDs) in real-world clinical settings. Deep Learning (DL) has recently emerged as a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Wajih Hassan Raza , Aamir Bader Shah , Yu Wen , Yidan Shen , Juan Diego Martinez Lemus , Mya Caryn Schiess , Timothy Michael Ellmore , Renjie Hu , Xin Fu

The estimation of time-varying networks for functional Magnetic Resonance Imaging (fMRI) data sets is of increasing importance and interest. In this work, we formulate the problem in a high-dimensional time series framework and introduce a…

Applications · Statistics 2016-06-24 Ivor Cribben , Yi Yu

Understanding how local neurophysiological patterns interact with global brain dynamics is essential for decoding human emotions from EEG signals. However, existing deep learning approaches often overlook the brain's intrinsic spatial…

Human-Computer Interaction · Computer Science 2026-01-16 Yijin Zhou , Fu Li , Yi Niu , Boxun Fu , Huaning Wang , Lijian Zhang

The human brain forms functional networks on all spatial scales. Modern fMRI scanners allow to resolve functional brain data in high resolutions, allowing to study large-scale networks that relate to cognitive processes. The analysis of…

Neurons and Cognition · Quantitative Biology 2019-05-14 Melanie Weber , Johannes Stelzer , Emil Saucan , Alexander Naitsat , Gabriele Lohmann , Jürgen Jost

Decoding visual experiences from fMRI offers a powerful avenue to understand human perception and develop advanced brain-computer interfaces. However, current progress often prioritizes maximizing reconstruction fidelity while overlooking…

Machine Learning · Computer Science 2025-10-09 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Tianyang Wang , Xiao Wang , Vince D. Calhoun

Reconstructing seeing images from fMRI recordings is an absorbing research area in neuroscience and provides a potential brain-reading technology. The challenge lies in that visual encoding in brain is highly complex and not fully revealed.…

Neural and Evolutionary Computing · Computer Science 2021-01-29 Tao Fang , Yu Qi , Gang Pan

Deciphering visual content from functional Magnetic Resonance Imaging (fMRI) helps illuminate the human vision system. However, the scarcity of fMRI data and noise hamper brain decoding model performance. Previous approaches primarily…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 Yulong Liu , Yongqiang Ma , Guibo Zhu , Haodong Jing , Nanning Zheng

Functional connectivity, as estimated using resting state fMRI, has shown potential in bridging the gap between pathophysiology and cognition. However, clinical use of functional connectivity biomarkers is impeded by unreliable estimates of…