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Electron tomography is a technique used in both materials science and structural biology to image features well below optical resolution limit. In this work, we present a new algorithm for reconstructing the three-dimensional(3D)…

Signal Processing · Electrical Eng. & Systems 2018-07-12 David Ren , Michael Chen , Laura Waller , Colin Ophus

For measurements designed to accurately determine layer thickness, there is a natural trade-off between sensitivity to optical thickness and lateral resolution due to the angular ray distribution required for a focused beam. We demonstrate…

Resolving single atoms in large-scale volumes has been a goal for atomic resolution microscopy for a long time. Electron microscopy has come close to this goal using a combination of advanced electron optics and computational imaging…

Materials Science · Physics 2023-11-07 Andrey Romanov , Min Gee Cho , Mary Cooper Scott , Colin Ophus , Philipp Pelz

Four-dimensional Scanning Transmission Electron Microscopy (4D STEM) with data acquired using a defocused electron probe is a promising tool for characterising complex biological specimens and materials through a phase retrieval process…

Signal Processing · Electrical Eng. & Systems 2025-05-15 Amirafshar Moshtaghpour , Angus I. Kirkland

X-ray ptychography utilizes overlapping illuminations to reconstruct the object's phase and absorption signal with spatial resolutions much smaller than the focus size. Usually, the illumination overlap is chosen to be between 50% and 60%…

Materials Science · Physics 2022-07-29 Felix Wittwer , Peter Modregger

This article presents a method to perform diffraction tomography in a standard microscope that includes an LED array for illumination. After acquiring a sequence of intensity-only images of a thick sample, a ptychography-based…

Optics · Physics 2015-10-30 Roarke Horstmeyer , Changhuei Yang

Tilting planar samples for multi-zone-axes observation is a routine procedure in electron microscopy. However, this process invariably introduces optical path differences in the electron beam across different sample positions, significantly…

Materials Science · Physics 2024-08-22 Jizhe Cui , Yi Zheng , Kang Sun , Wenfeng Yang , Haozhi Sha , Rong Yu

Circular dichroism spectroscopy is an essential technique for understanding molecular structure and magnetic materials, but spatial resolution is limited by the wavelength of light, and sensitivity sufficient for single-molecule…

Ptychography is a data-intensive computational imaging technique that achieves high spatial resolution over large fields of view. The technique involves scanning a coherent beam across overlapping regions and recording diffraction patterns.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-14 Refik Mert Cam , Junjing Deng , Rajkumar Kettimuthu , Mathew J. Cherukara , Tekin Bicer

Ptychography has rapidly grown in the fields of X-ray and electron imaging for its unprecedented ability to achieve nano or atomic scale resolution while simultaneously retrieving chemical or magnetic information from a sample. A…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Mathew J. Cherukara , Tao Zhou , Youssef Nashed , Pablo Enfedaque , Alex Hexemer , Ross J. Harder , Martin V. Holt

Atomic-scale characterization of spin textures in solids is essential for understanding and tuning properties of magnetic materials and devices. While high-energy electrons are employed for atomic-scale imaging of materials, they are…

Materials Science · Physics 2023-12-29 Jizhe Cui , Haozhi Sha , Wenfeng Yang , Rong Yu

Ptychographic reconstructions in reflection geometries are commonly interpreted with the same two-dimensional thin-sample model used in transmission, yet the validity of this approximation has not been established. We develop a…

Optics · Physics 2026-04-08 Sander Senhorst , Stefan Witte , Wim Coene

Ptychography provides highly efficient imaging in scanning transmission electron microscopy (STEM), but questions have remained over its applicability to strongly scattering samples such as those most commonly seen in materialsscience.…

Applied Physics · Physics 2022-09-07 C. Gao , C. Hofer , D. Jannis , A. Béché , J. Verbeeck , T. J. Pennycook

Ptychography is a scanning coherent diffractive imaging technique that enables imaging nanometer-scale features in extended samples. One main challenge is that widely used iterative image reconstruction methods often require significant…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Canberk Ekmekci , Tekin Bicer , Zichao Wendy Di , Junjing Deng , Mujdat Cetin

Thin film oxides are a source of endless fascination for the materials scientist. These materials are highly flexible, can be integrated into almost limitless combinations, and exhibit many useful functionalities for device applications.…

Materials Science · Physics 2025-06-17 Steven R. Spurgeon

Recent advances in scanning transmission electron and scanning probe microscopies have opened exciting opportunities in probing the materials structural parameters and various functional properties in real space with angstrom-level…

Direct ptychography enables the retrieval of information encoded in the phase of an electron wave passing through a thin sample by deconvolving the interference effects of a converged probe with known aberrations. Under the weak phase…

High quality scanning transmission electron microscopy (STEM) data acquisition and analysis has become increasingly important due to the commercial demand for investigating the properties of complex materials such as battery cathodes;…

Serial section electron microscopy (ssEM) is a widely used technique for obtaining volumetric information of biological tissues at nanometer scale. However, accurate 3D reconstructions of identified cellular structures and volumetric…

Image and Video Processing · Electrical Eng. & Systems 2020-02-06 Thanuja D. Ambegoda , Julien N. P. Martel , Jozef Adamcik , Matthew Cook , Richard H. R. Hahnloser

Non-line-of-sight (NLOS) imaging enables the visualization of objects hidden from direct view, with applications in surveillance, remote sensing, and light detection and ranging. Here, we introduce a NLOS imaging technique termed…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Pengming Song , Qianhao Zhao , Ruihai Wang , Ninghe Liu , Yingqi Qiang , Tianbo Wang , Xincheng Zhang , Yi Zhang , Guoan Zheng