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Simulating human profiles by instilling personas into large language models (LLMs) is rapidly transforming research in agentic behavioral simulation, LLM personalization, and human-AI alignment. However, most existing synthetic personas…

Artificial Intelligence · Computer Science 2025-12-02 Zhen Wang , Yufan Zhou , Zhongyan Luo , Lyumanshan Ye , Adam Wood , Man Yao , Saab Mansour , Luoshang Pan

Large Language Models (LLMs) have demonstrated remarkable capabilities in reasoning and generation, serving as the foundation for advanced persona simulation and Role-Playing Language Agents (RPLAs). However, achieving authentic alignment…

Computation and Language · Computer Science 2026-04-20 Xintao Wang , Jian Yang , Weiyuan Li , Rui Xie , Jen-tse Huang , Jun Gao , Shuai Huang , Yueping Kang , Yuanli Gou , Hongwei Feng , Yanghua Xiao

With the advancement of large language models, many dialogue systems are now capable of providing reasonable and informative responses to patients' medical conditions. However, when patients consult their doctor, they may experience…

Computation and Language · Computer Science 2025-06-17 Shang-Chi Tsai , Yun-Nung Chen

Access to mental health support remains limited, particularly in marginalized communities where structural and cultural barriers hinder timely care. This paper explores the potential of AI-enabled chatbots as a scalable solution, focusing…

Computers and Society · Computer Science 2024-10-07 Rawan AlMakinah , Andrea Norcini-Pala , Lindsey Disney , M. Abdullah Canbaz

Objectives: While Large Language Models (LLMs) have been widely used to assist clinicians and support patients, no existing work has explored dialogue systems for standard diagnostic interviews and assessments. This study aims to bridge the…

Computation and Language · Computer Science 2025-05-01 Sichang Tu , Abigail Powers , Stephen Doogan , Jinho D. Choi

The prevailing paradigm in the domain of Open-Domain Dialogue agents predominantly focuses on the English language, encompassing both models and datasets. Furthermore, the financial and temporal investments required for crowdsourcing such…

Computation and Language · Computer Science 2025-03-06 Ahmed Njifenjou , Virgile Sucal , Bassam Jabaian , Fabrice Lefèvre

Large Language Models (LLMs) have revolutionized Natural Language Processing but exhibit limitations, particularly in autonomously addressing novel challenges such as reasoning and problem-solving. Traditional techniques like…

Multiagent Systems · Computer Science 2024-01-03 Sumedh Rasal

Synthetic data generation using large language models (LLMs) demonstrates substantial promise in addressing biomedical data challenges and shows increasing adoption in biomedical research. This study systematically reviews recent advances…

Computation and Language · Computer Science 2026-02-18 Hanshu Rao , Weisi Liu , Haohan Wang , I-Chan Huang , Zhe He , Xiaolei Huang

In recent years, with the rapid advancements in large language models (LLMs), achieving excellent empathetic response capability has become a crucial prerequisite. Consequently, managing and understanding large-scale video datasets has…

Computation and Language · Computer Science 2024-07-10 Linzhuang Sun , Hao Liang , Jingxuan Wei , Linkun Sun , Bihui Yu , Bin Cui , Wentao Zhang

This paper investigates the capacity of small language models (0.5B-5B parameters) to generate empathetic responses for individuals with PTSD. We introduce Trauma-Informed Dialogue for Empathy (TIDE), a novel dataset comprising 10,000…

Computation and Language · Computer Science 2025-09-23 Suhas BN , Yash Mahajan , Dominik Mattioli , Andrew M. Sherrill , Rosa I. Arriaga , Chris W. Wiese , Saeed Abdullah

Empathetic Conversational Systems (ECS) are built to respond empathetically to the user's emotions and sentiments, regardless of the application domain. Current ECS studies evaluation approaches are restricted to offline evaluation…

Computation and Language · Computer Science 2024-07-29 Aravind Sesagiri Raamkumar , Siyuan Brandon Loh

Linear programming (LP) problems are pervasive in real-life applications. However, despite their apparent simplicity, an untrained user may find it difficult to determine the linear model of their specific problem. We envisage the creation…

Computation and Language · Computer Science 2024-02-01 Yelaman Abdullin , Diego Molla-Aliod , Bahadorreza Ofoghi , John Yearwood , Qingyang Li

An important issue impacting healthcare is a lack of available experts. Machine learning (ML) models could resolve this by aiding in diagnosing patients. However, creating datasets large enough to train these models is expensive. We…

Computation and Language · Computer Science 2024-05-14 Chancellor R. Woolsey , Prakash Bisht , Joshua Rothman , Gondy Leroy

Synthetic therapy dialogues generated by large language models (LLMs) are increasingly used in mental health NLP to simulate counseling scenarios, train models, and supplement limited real-world data. However, it remains unclear whether…

Computation and Language · Computer Science 2025-12-18 Xiaoyi Wang , Jiwei Zhang , Guangtao Zhang , Honglei Guo

Large language models (LLMs) show promise in generating supportive responses for mental health queries, but improving their usefulness, empathy, and safety often requires substantial compute, expert input, and labeled data. At the same…

Human-Computer Interaction · Computer Science 2026-05-29 Jiwon Kim , Maya Ajit , Sherry Gong , Soorya Ram Shimgekar , Dong Whi Yoo , Eshwar Chandrasekharan , Koustuv Saha

Mental health support in colleges is vital in educating students by offering counseling services and organizing supportive events. However, evaluating its effectiveness faces challenges like data collection difficulties and lack of…

Computation and Language · Computer Science 2024-12-06 Palak Sood , Chengyang He , Divyanshu Gupta , Yue Ning , Ping Wang

Large Language Models (LLMs),such as ChatGPT, are increasingly used in research, ranging from simple writing assistance to complex data annotation tasks. Recently, some research has suggested that LLMs may even be able to simulate human…

Artificial Intelligence · Computer Science 2025-08-14 Sarah Schröder , Thekla Morgenroth , Ulrike Kuhl , Valerie Vaquet , Benjamin Paaßen

In the literature, existing human-centric emotional motion generation methods primarily focus on boosting performance within a single scale-fixed dataset, largely neglecting the flexible and scale-increasing motion scenarios (e.g., sports,…

Artificial Intelligence · Computer Science 2025-12-23 Jiawen Wang , Jingjing Wang Tianyang Chen , Min Zhang , Guodong Zhou

Large Language Models (LLMs) have demonstrated impressive capabilities in role-playing scenarios, particularly in simulating domain-specific experts using tailored prompts. This ability enables LLMs to adopt the persona of individuals with…

Artificial Intelligence · Computer Science 2025-01-14 Xinyao Ma , Rui Zhu , Zihao Wang , Jingwei Xiong , Qingyu Chen , Haixu Tang , L. Jean Camp , Lucila Ohno-Machado

AI-based persona simulation -- often referred to as digital twin simulation -- is increasingly used for market research, recommender systems, and social sciences. Despite their flexibility, large language models (LLMs) often exhibit…

Machine Learning · Computer Science 2026-04-10 Grace Jiarui Fan , Chengpiao Huang , Tianyi Peng , Kaizheng Wang , Yuhang Wu
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