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The detection of heterogeneous mental disorders based on brain readouts remains challenging due to the complexity of symptoms and the absence of reliable biomarkers. This paper introduces CAM (Cortical Anomaly Detection through Masked Image…

Image and Video Processing · Electrical Eng. & Systems 2024-02-14 Hao-Chun Yang , Ole Andreassen , Lars Tjelta Westlye , Andre F. Marquand , Christian F. Beckmann , Thomas Wolfers

This review explores anomaly localization in medical images using denoising diffusion models. After providing a brief methodological background of these models, including their application to image reconstruction and their conditioning…

Image and Video Processing · Electrical Eng. & Systems 2025-12-15 Cosmin I. Bercea , Philippe C. Cattin , Julia A. Schnabel , Julia Wolleb

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

Deep unsupervised approaches are gathering increased attention for applications such as pathology detection and segmentation in medical images since they promise to alleviate the need for large labeled datasets and are more generalizable…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Ioannis Lagogiannis , Felix Meissen , Georgios Kaissis , Daniel Rueckert

Anomaly detection (AD) aims at detecting abnormal samples that deviate from the expected normal patterns. Generally, it can be trained merely on normal data, without a requirement for abnormal samples, and thereby plays an important role in…

Computer Vision and Pattern Recognition · Computer Science 2025-02-20 Yu Cai , Weiwen Zhang , Hao Chen , Kwang-Ting Cheng

The quality of patient care associated with diagnostic radiology is proportionate to a physician workload. Segmentation is a fundamental limiting precursor to both diagnostic and therapeutic procedures. Advances in machine learning (ML) aim…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Ahmed Ghorbel , Ahmed Aldahdooh , Shadi Albarqouni , Wassim Hamidouche

Decoding visual stimuli from brain recordings aims to deepen our understanding of the human visual system and build a solid foundation for bridging human and computer vision through the Brain-Computer Interface. However, reconstructing…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Zijiao Chen , Jiaxin Qing , Tiange Xiang , Wan Lin Yue , Juan Helen Zhou

In the context of flexible manufacturing systems that are required to produce different types and quantities of products with minimal reconfiguration, this paper addresses the problem of unsupervised multi-class anomaly detection: develop a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-18 Haonan Yin , Guanlong Jiao , Qianhui Wu , Borje F. Karlsson , Biqing Huang , Chin Yew Lin

As advancements in the field of breast cancer treatment continue to progress, the assessment of post-surgical cosmetic outcomes has gained increasing significance due to its substantial impact on patients' quality of life. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Sangjoon Park , Yong Bae Kim , Jee Suk Chang , Seo Hee Choi , Hyungjin Chung , Ik Jae Lee , Hwa Kyung Byun

Anomaly detection (AD) is a crucial machine learning task that aims to learn patterns from a set of normal training samples to identify abnormal samples in test data. Most existing AD studies assume that the training and test data are drawn…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Tri Cao , Jiawen Zhu , Guansong Pang

Unsupervised anomaly detection aims to build models to effectively detect unseen anomalies by only training on the normal data. Although previous reconstruction-based methods have made fruitful progress, their generalization ability is…

Machine Learning · Computer Science 2022-01-04 Yuxin Zhang , Jindong Wang , Yiqiang Chen , Han Yu , Tao Qin

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

Unsupervised out-of-distribution detection (OOD) seeks to identify out-of-domain data by learning only from unlabeled in-domain data. We present a novel approach for this task - Lift, Map, Detect (LMD) - that leverages recent advancement in…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Zhenzhen Liu , Jin Peng Zhou , Yufan Wang , Kilian Q. Weinberger

Anomaly detection (AD) is a critical task across domains such as cybersecurity and healthcare. In the unsupervised setting, an effective and theoretically-grounded principle is to train classifiers to distinguish normal data from…

Machine Learning · Statistics 2025-06-18 Matthew Lau , Tian-Yi Zhou , Xiangchi Yuan , Jizhou Chen , Wenke Lee , Xiaoming Huo

Although mainstream unsupervised anomaly detection (AD) (including image-level classification and pixel-level segmentation)algorithms perform well in academic datasets, their performance is limited in practical application due to the ideal…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Chengjie Wang , Xi Jiang , Bin-Bin Gao , Zhenye Gan , Yong Liu , Feng Zheng , Lizhuang Ma

Discrete diffusion models have recently shown great promise for modeling complex discrete data, with masked diffusion models (MDMs) offering a compelling trade-off between quality and generation speed. MDMs denoise by progressively…

Machine Learning · Computer Science 2026-04-15 Tianyu Xie , Shuchen Xue , Zijin Feng , Tianyang Hu , Jiacheng Sun , Zhenguo Li , Cheng Zhang

Computer-aided diagnosis for low-dose computed tomography (CT) based on deep learning has recently attracted attention as a first-line automatic testing tool because of its high accuracy and low radiation exposure. However, existing methods…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Kyung-Su Kim , Seong Je Oh , Ju Hwan Lee , Myung Jin Chung

Unsupervised anomaly detection methods offer a promising and flexible alternative to supervised approaches, holding the potential to revolutionize medical scan analysis and enhance diagnostic performance. In the current landscape, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Cosmin I. Bercea , Esther Puyol-Antón , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel , Andrew P. King

Unsupervised anomaly segmentation approaches to pathology segmentation train a model on images of healthy subjects, that they define as the 'normal' data distribution. At inference, they aim to segment any pathologies in new images as…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Ziyun Liang , Xiaoqing Guo , J. Alison Noble , Konstantinos Kamnitsas
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