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The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has…

Machine Learning · Computer Science 2026-04-30 Yunkun Zhang , Jin Gao , Zheling Tan , Lingfeng Zhou , Kexin Ding , Mu Zhou , Shaoting Zhang , Dequan Wang

In the rapidly evolving field of artificial intelligence, large language models (LLMs) have emerged as powerful tools for a myriad of applications, from natural language processing to decision-making support systems. However, as these…

Computation and Language · Computer Science 2025-07-08 Jianchao Ji , Yutong Chen , Mingyu Jin , Wujiang Xu , Wenyue Hua , Yongfeng Zhang

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

The role of artificial intelligence (AI) in pathology has evolved from aiding diagnostics to uncovering predictive morphological patterns in whole slide images (WSIs). Recently, foundation models (FMs) leveraging self-supervised…

Research in Responsible AI has developed a range of principles and practices to ensure that machine learning systems are used in a manner that is ethical and aligned with human values. However, a critical yet often neglected aspect of…

Computers and Society · Computer Science 2024-08-21 Neha R. Gupta , Jessica Hullman , Hari Subramonyam

Ensuring equitable Artificial Intelligence (AI) in healthcare demands systems that make unbiased decisions across all demographic groups, bridging technical innovation with ethical principles. Foundation Models (FMs), trained on vast…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Dilermando Queiroz , Anderson Carlos , André Anjos , Lilian Berton

The deep integration of foundation models (FM) with federated learning (FL) enhances personalization and scalability for diverse downstream tasks, making it crucial in sensitive domains like healthcare. Achieving group fairness has become…

Machine Learning · Computer Science 2025-06-24 Yuning Yang , Han Yu , Tianrun Gao , Xiaodong Xu , Guangyu Wang

Clinical prediction models are statistical or machine learning models used to quantify the risk of a certain health outcome using patient data. These can then inform potential interventions on patients, causing an effect called performative…

Machine Learning · Computer Science 2024-06-06 Louis Chislett , Louis JM Aslett , Alisha R Davies , Catalina A Vallejos , James Liley

Large language models (LLMs) demonstrate significant potential in advancing medical applications, yet their capabilities in addressing medical ethics challenges remain underexplored. This paper introduces MedEthicEval, a novel benchmark…

Computation and Language · Computer Science 2025-03-05 Haoan Jin , Jiacheng Shi , Hanhui Xu , Kenny Q. Zhu , Mengyue Wu

The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable…

Machine Learning · Statistics 2021-06-16 Stephen R. Pfohl , Agata Foryciarz , Nigam H. Shah

With the introduction of ChatGPT, Large Language Models (LLMs) have received enormous attention in healthcare. Despite their potential benefits, researchers have underscored various ethical implications. While individual instances have…

Computers and Society · Computer Science 2024-07-09 Joschka Haltaufderheide , Robert Ranisch

Moral values have deep roots in early civilizations, codified within norms and laws that regulated societal order and the common good. They play a crucial role in understanding the psychological basis of human behavior and cultural…

Computation and Language · Computer Science 2025-04-07 Lorenzo Zangari , Candida M. Greco , Davide Picca , Andrea Tagarelli

The escalating integration of machine learning in high-stakes fields such as healthcare raises substantial concerns about model fairness. We propose an interpretable framework - Fairness-Aware Interpretable Modeling (FAIM), to improve model…

Machine Learning · Computer Science 2024-03-11 Mingxuan Liu , Yilin Ning , Yuhe Ke , Yuqing Shang , Bibhas Chakraborty , Marcus Eng Hock Ong , Roger Vaughan , Nan Liu

The adoption of Artificial Intelligence (AI) in the healthcare service industry presents numerous ethical challenges, yet current frameworks often fail to offer a comprehensive, empirical understanding of the multidimensional factors…

Artificial Intelligence · Computer Science 2025-05-06 Prathamesh Muzumdar , Apoorva Muley , Kuldeep Singh , Sumanth Cheemalapati

We review practical challenges in building and deploying ethical AI at the scale of contemporary industrial and societal uses. Apart from the purely technical concerns that are the usual focus of academic research, the operational…

Machine Learning · Computer Science 2021-08-16 Jiahao Chen , Victor Storchan , Eren Kurshan

Big models have greatly advanced AI's ability to understand, generate, and manipulate information and content, enabling numerous applications. However, as these models become increasingly integrated into everyday life, their inherent…

Computers and Society · Computer Science 2023-10-27 Xiaoyuan Yi , Jing Yao , Xiting Wang , Xing Xie

Moral cognition is a crucial yet underexplored aspect of decision-making in AI models. Regardless of the application domain, it should be a consideration that allows for ethically aligned decision-making. This paper presents a multifaceted…

Computers and Society · Computer Science 2026-02-17 Aisha Aijaz , Raghava Mutharaju , Manohar Kumar

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

The increasing integration of large language models (LLMs) into mental health applications necessitates robust frameworks for evaluating professional safety alignment. Current evaluative approaches primarily rely on refusal-based safety…

Computation and Language · Computer Science 2026-01-08 Yaling Shen , Stephanie Fong , Yiwen Jiang , Zimu Wang , Feilong Tang , Qingyang Xu , Xiangyu Zhao , Zhongxing Xu , Jiahe Liu , Jinpeng Hu , Dominic Dwyer , Zongyuan Ge

Pathology foundation models (PFMs) have become central to computational pathology, aiming to offer general encoders for feature extraction from whole-slide images (WSIs). Despite strong benchmark performance, PFM robustness to real-world…

Image and Video Processing · Electrical Eng. & Systems 2026-01-08 Erik Thiringer , Fredrik K. Gustafsson , Kajsa Ledesma Eriksson , Mattias Rantalainen