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Exposure mixtures frequently occur in data across many domains, particularly in the fields of environmental and nutritional epidemiology. Various strategies have arisen to answer questions about mixtures, including methods such as weighted…

Humans are exposed to complex mixtures of environmental pollutants rather than single chemicals, necessitating methods to quantify the health effects of such mixtures. Research on environmental mixtures provides insights into realistic…

Methodology · Statistics 2026-04-09 Aaron Sonabend , Jiangshan Zhang , Edgar Castro , Joel Schwartz , Brent A. Coull , Junwei Lu

Investigating relationships between response variables and covariates in areas such as environmental science, geoscience, and public health is an important endeavor. Based on a Bayesian mixture of finite mixtures model, we present a novel…

Methodology · Statistics 2023-06-06 Peng Zhao , Hou-Cheng Yang , Dipak K. Dey , Guanyu Hu

Epidemiological evidence supports an association between exposure to air pollution during pregnancy and birth and child health outcomes. Typically, such associations are estimated by regressing an outcome on daily or weekly measures of…

Maternal exposure to environmental chemicals during pregnancy can alter birth and children's health outcomes. Research seeks to identify critical windows, time periods when the exposures can change future health outcomes, and estimate the…

Methodology · Statistics 2022-04-14 Daniel Mork , Ander Wilson

Fine particulate matter (PM2.5) measured at a given location is a mix of pollution generated locally and pollution traveling long distances in the atmosphere. Therefore, the identification of spatial scales associated with health effects…

Methodology · Statistics 2016-09-19 Joseph Antonelli , Joel Schwartz , Itai Kloog , Brent Coull

Motivated by analyzing a national data base of annual air pollution and cardiovascular disease mortality rate for 3100 counties in the U.S. (areal data), we develop a novel statistical framework to automatically detect spatially varying…

Applications · Statistics 2015-11-19 Shuo Chen , Chengsheng Jiang , Lance Waller

Children's health studies support an association between maternal environmental exposures and children's birth outcomes. A common goal is to identify critical windows of susceptibility--periods during gestation with increased association…

Estimation of the long-term health effects of air pollution is a challenging task, especially when modelling small-area disease incidence data in an ecological study design. The challenge comes from the unobserved underlying spatial…

Methodology · Statistics 2013-05-24 Duncan Lee , Alastair Rushworth , Sujit K. Sahu

Spatial statistical models are commonly used in geographical scenarios to ensure spatial variation is captured effectively. However, spatial models and cluster algorithms can be complicated and expensive. This paper pursues three main…

Studying the association between mixtures of environmental exposures and health outcomes can be challenging due to issues such as correlation among the exposures and non-linearities or interactions in the exposure-response function. For…

Applications · Statistics 2024-11-15 Jacob Englert , Stefanie Ebelt , Howard Chang

Understanding the role of time-varying pollution mixtures on human health is critical as people are simultaneously exposed to multiple pollutants during their lives. For vulnerable sub-populations who have well-defined exposure periods…

This manuscript presents a novel Bayesian varying coefficient quantile regression (BVCQR) model designed to assess the longitudinal effects of chemical exposure mixtures on children's neurodevelopment. Recognizing the complexity and…

Applications · Statistics 2024-04-22 Wei Jia , Roman Jandarov

Airborne particulate matter (PM2.5) is a major public health concern in urban environments, where population density and emission sources exacerbate exposure risks. We present a novel Bayesian spatiotemporal fusion model to estimate monthly…

The impact of wildfire smoke on air quality is a growing concern, contributing to air pollution through a complex mixture of chemical species with important implications for public health. While previous studies have primarily focused on…

Methodology · Statistics 2026-02-10 Dafne Zorzetto , Jenna Landy , Corwin Zigler , Giovanni Parmigiani , Roberta De Vito

Air pollution remains a major environmental risk factor that is often associated with adverse health outcomes. However, quantifying and evaluating its effects on human health is challenging due to the complex nature of exposure data. Recent…

Methodology · Statistics 2025-06-02 Soumyakanti Pan , Sudipto Banerjee

Exposures to environmental chemicals during gestation can alter health status later in life. Most studies of maternal exposure to chemicals during pregnancy have focused on a single chemical exposure observed at high temporal resolution.…

Distributed lag models are useful in environmental epidemiology as they allow the user to investigate critical windows of exposure, defined as the time period during which exposure to a pollutant adversely affects health outcomes. Recent…

Methodology · Statistics 2021-08-02 Joseph Antonelli , Ander Wilson , Brent Coull

Ambient air pollution poses significant health and environmental challenges. Exposure to high concentrations of PM$_{2.5}$ have been linked to increased respiratory and cardiovascular hospital admissions, more emergency department visits…

Applications · Statistics 2026-02-27 Zeinab Mohamed , Wenlong Gong

A typical problem in air pollution epidemiology is exposure assessment for individuals for which health data are available. Due to the sparsity of monitoring sites and the limited temporal frequency with which measurements of air pollutants…

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