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Environmental epidemiologic studies routinely utilize aggregate health outcomes to estimate effects of short-term (e.g., daily) exposures that are available at increasingly fine spatial resolutions. However, areal averages are typically…

Applications · Statistics 2023-02-07 Yuzi Zhang , Howard H. Chang , Joshua L. Warren , Stefanie T. Ebelt

We present an approach to estimate distance-dependent heterogeneous associations between point-referenced exposures to built environment characteristics and health outcomes. By estimating associations that depend non-linearly on distance…

Methodology · Statistics 2021-07-14 Adam Peterson , Emma Sanchez-Vaznaugh , Brisa Sanchez

Humans are routinely exposed to mixtures of chemical and other environmental factors, making the quantification of health effects associated with environmental mixtures a critical goal for establishing environmental policy sufficiently…

The health impact of long-term exposure to air pollution is now routinely estimated using spatial ecological studies, due to the recent widespread availability of spatial referenced pollution and disease data. However, this areal unit study…

Applications · Statistics 2014-12-16 Duncan Lee , Christophe Sarran

In air pollution studies, dispersion models provide estimates of concentration at grid level covering the entire spatial domain, and are then calibrated against measurements from monitoring stations. However, these different data sources…

Applications · Statistics 2020-08-17 Chiara Forlani , Samir Bhatt , Michela Cameletti , Elias Krainski , Marta Blangiardo

This paper presents an approach to estimating the health effects of an environmental hazard. The approach is general in nature, but is applied here to the case of air pollution. It uses a computer model involving ambient pollution and…

Applications · Statistics 2007-11-01 Gavin Shaddick , Duncan Lee , James V. Zidek , Ruth Salway

An important goal of environmental health research is to assess the health risks posed by mixtures of multiple environmental exposures. In these mixtures analyses, flexible models like Bayesian kernel machine regression and multiple index…

Methodology · Statistics 2025-12-29 Glen McGee , Joseph Antonelli

Statistical techniques used in air pollution modelling usually lack the possibility to understand which predictors affect air pollution in which functional form; and are not able to regress on exceedances over certain thresholds imposed by…

Methodology · Statistics 2021-05-25 Nadja Klein , Jorge Mateu

An important goal of environmental health research is to assess the risk posed by mixtures of environmental exposures. Two popular classes of models for mixtures analyses are response-surface methods and exposure-index methods.…

Methodology · Statistics 2025-05-01 Glen McGee , Ander Wilson , Thomas F. Webster , Brent A. Coull

In regional economics research, a problem of interest is to detect similarities between regions, and estimate their shared coefficients in economics models. In this article, we propose a mixture of finite mixtures (MFM) clustered regression…

Methodology · Statistics 2021-08-31 Guanyu Hu , Yishu Xue , Zhihua Ma

The relationship between short-term exposure to air pollution and mortality or morbidity has been the subject of much recent research, in which the standard method of analysis uses Poisson linear or additive models. In this paper we use a…

Applications · Statistics 2012-01-27 Duncan Lee , Gavin Shaddick

Estimating the joint effect of a multivariate, continuous exposure is crucial, particularly in environmental health where interest lies in simultaneously evaluating the impact of multiple environmental pollutants on health. We develop novel…

We present a novel approach for the analysis of multivariate case-control georeferenced data using Bayesian inference in the context of disease mapping, where the spatial distribution of different types of cancers is analyzed. Extending…

We develop new methodology to improve our understanding of the causal effects of multivariate air pollution exposures on public health. Typically, exposure to air pollution for an individual is measured at their home geographic region,…

Methodology · Statistics 2025-11-18 Heejun Shin , Danielle Braun , Kezia Irene , Michelle Audirac , Joseph Antonelli

Income inequality is a major contributor to health disparities, yet its effects often vary by geography and are commonly represented as compositional distributions (e.g., proportions of households across income brackets). Existing spatial…

Methodology · Statistics 2026-05-18 Jingwen Deng , Shujie Ma , Sergio J. Rey , Guanyu Hu

Leveraging multivariate spatial dependence to improve the precision of estimates using American Community Survey data and other sample survey data has been a topic of recent interest among data-users and federal statistical agencies. One…

Applications · Statistics 2024-01-19 Ryan Janicki , Andrew M. Raim , Scott H. Holan , Jerry Maples

The estimation of the effect of environmental exposures and overall mixtures on a survival time outcome is common in environmental epidemiological studies. While advanced statistical methods are increasingly being used for mixture analyses,…

Maternal exposure to air pollution during pregnancy has a substantial public health impact. Epidemiological evidence supports an association between maternal exposure to air pollution and low birth weight. A popular method to estimate this…

We develop a Gaussian-process mixture model for heterogeneous treatment effect estimation that leverages the use of transformed outcomes. The approach we will present attempts to improve point estimation and uncertainty quantification…

Methodology · Statistics 2018-12-19 Abbas Zaidi , Sayan Mukherjee

Occupancy models are frequently used by ecologists to quantify spatial variation in species distributions while accounting for observational biases in the collection of detection-nondetection data. However, the common assumption that a…