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This paper audits benchmark evaluation in clinical-interview depression detection through four complementary probes across DAIC/E-DAIC, CMDC, ANDROIDS, MODMA, and PDCH. First, we re-evaluate E-DAIC under strict subject-disjoint…

Computation and Language · Computer Science 2026-05-26 Takehiro Ishikawa , Jon Duke

Clinical depression or Major Depressive Disorder (MDD) is a common and serious medical illness. In this paper, a deep recurrent neural network-based framework is presented to detect depression and to predict its severity level from speech.…

Human-Computer Interaction · Computer Science 2020-03-13 Emna Rejaibi , Ali Komaty , Fabrice Meriaudeau , Said Agrebi , Alice Othmani

Anxiety and depression are the most common mental health issues worldwide, affecting a non-negligible part of the population. Accordingly, stakeholders, including governments' health systems, are developing new strategies to promote early…

Artificial Intelligence · Computer Science 2024-12-24 Francisco de Arriba-Pérez , Silvia García-Méndez

Advances in large language models (LLMs) have enabled a wide range of applications. However, depression prediction is hindered by the lack of large-scale, high-quality, and rigorously annotated datasets. This study introduces DepressLLM,…

Computation and Language · Computer Science 2025-08-13 Sehwan Moon , Aram Lee , Jeong Eun Kim , Hee-Ju Kang , Il-Seon Shin , Sung-Wan Kim , Jae-Min Kim , Min Jhon , Ju-Wan Kim

With the emergence of AI techniques for depression diagnosis, the conflict between high demand and limited supply for depression screening has been significantly alleviated. Among various modal data, audio-based depression diagnosis has…

Cryptography and Security · Computer Science 2026-03-27 Xintao Hu , Feng-Qi Cui

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

Depression remains widely underdiagnosed and undertreated because stigma and subjective symptom ratings hinder reliable screening. To address this challenge, we propose a coarse-to-fine, multi-stage framework that leverages large language…

Artificial Intelligence · Computer Science 2026-04-14 Shiyu Teng , Jiaqing Liu , Hao Sun , Yu Li , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-Wei Chen

Depression-diagnosis-oriented chat aims to guide patients in self-expression to collect key symptoms for depression detection. Recent work focuses on combining task-oriented dialogue and chitchat to simulate the interview-based depression…

Human-Computer Interaction · Computer Science 2025-08-21 Yiyang Gu , Yougen Zhou , Qin Chen , Ningning Zhou , Jie Zhou , Aimin Zhou , Liang He

This paper proposes a new depression detection system based on LLMs that is both interpretable and interactive. It not only provides a diagnosis, but also diagnostic evidence and personalized recommendations based on natural language…

Computation and Language · Computer Science 2023-05-10 Wei Qin , Zetong Chen , Lei Wang , Yunshi Lan , Weijieying Ren , Richang Hong

Depression is a common and serious mood disorder that negatively affects the patient's capacity of functioning normally in daily tasks. Speech is proven to be a vigorous tool in depression diagnosis. Research in psychiatry concentrated on…

Sound · Computer Science 2020-11-05 Muhammad Muzammel , Hanan Salam , Yann Hoffmann , Mohamed Chetouani , Alice Othmani

In this study, we focus on automated approaches to detect depression from clinical interviews using multi-modal machine learning (ML). Our approach differentiates from other successful ML methods such as context-aware analysis through…

Machine Learning · Computer Science 2024-12-30 Genevieve Lam , Huang Dongyan , Weisi Lin

Depression is a serious medical condition that is suffered by a large number of people around the world. It significantly affects the way one feels, causing a persistent lowering of mood. In this paper, we propose a novel attention-based…

Computers and Society · Computer Science 2019-04-17 Syed Arbaaz Qureshi , Mohammed Hasanuzzaman , Sriparna Saha , Gaël Dias

Depression has been the leading cause of mental-health illness worldwide. Major depressive disorder (MDD), is a common mental health disorder that affects both psychologically as well as physically which could lead to loss of lives. Due to…

Computer Vision and Pattern Recognition · Computer Science 2019-09-05 Anupama Ray , Siddharth Kumar , Rutvik Reddy , Prerana Mukherjee , Ritu Garg

Identifying physiological and behavioral markers for mental health conditions is a longstanding challenge in psychiatry. Depression and suicidal ideation, in particular, lack objective biomarkers, with screening and diagnosis primarily…

Audio-based depression detection models have demonstrated promising performance but often suffer from gender bias due to imbalanced training data. Epidemiological statistics show a higher prevalence of depression in females, leading models…

Machine Learning · Computer Science 2026-02-04 Mingxuan Hu , Hongbo Ma , Xinlan Wu , Ziqi Liu , Jiaqi Liu , Yangbin Chen

This study investigates whether speech-based depression detection models learn depression-related acoustic biomarkers or instead rely on speaker identity cues. Using the DAIC-WOZ dataset, we propose a data-splitting strategy that controls…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-17 Hsiang-Chen Yeh , Luqi Sun , Aurosweta Mahapatra , Shreeram Suresh Chandra , Emily Mower Provost , Berrak Sisman

Depression has proven to be a significant public health issue, profoundly affecting the psychological well-being of individuals. If it remains undiagnosed, depression can lead to severe health issues, which can manifest physically and even…

Human-Computer Interaction · Computer Science 2024-12-03 Chayan Tank , Sarthak Pol , Vinayak Katoch , Shaina Mehta , Avinash Anand , Rajiv Ratn Shah

With the acceleration of the pace of work and life, people have to face more and more pressure, which increases the possibility of suffering from depression. However, many patients may fail to get a timely diagnosis due to the serious…

Signal Processing · Electrical Eng. & Systems 2021-06-02 Lang He , Mingyue Niu , Prayag Tiwari , Pekka Marttinen , Rui Su , Jiewei Jiang , Chenguang Guo , Hongyu Wang , Songtao Ding , Zhongmin Wang , Wei Dang , Xiaoying Pan

Depression manifests through a diverse set of symptoms such as sleep disturbance, loss of interest, and concentration difficulties. However, most existing works treat depression prediction either as a binary label or an overall severity…

Computation and Language · Computer Science 2026-02-18 Chaithra Nerella , Chiranjeevi Yarra

Depression is a highly prevalent and disabling condition that incurs substantial personal and societal costs. Current depression diagnosis involves determining the depression severity of a person through self-reported questionnaires or…

Computation and Language · Computer Science 2025-03-27 Aishik Mandal , Dana Atzil-Slonim , Thamar Solorio , Iryna Gurevych