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Posterior sampling with the spike-and-slab prior [MB88], a popular multimodal distribution used to model uncertainty in variable selection, is considered the theoretical gold standard method for Bayesian sparse linear regression [CPS09,…

Machine Learning · Statistics 2025-03-05 Syamantak Kumar , Purnamrita Sarkar , Kevin Tian , Yusong Zhu

We propose a new framework for the analysis of current and future cosmological surveys, which combines perturbative methods (PT) on large scales with conditional simulation-based implicit inference (SBI) on small scales. This enables…

Cosmology and Nongalactic Astrophysics · Physics 2023-09-20 Chirag Modi , Oliver H. E. Philcox

Simulation Based Inference (SBI) is shown to yield more accurate resonance parameter estimates than traditional chi-squared minimization in certain cases of model misspecification, demonstrated through a case study of pi-pi scattering and…

High Energy Physics - Phenomenology · Physics 2025-07-28 Daniel Sadasivan , Isaac Cordero , Andrew Graham , Cecilia Marsh , Daniel Kupcho , Melana Mourad , Maxim Mai

Gravitational-wave parameter estimation for binary neutron star (BNS) systems poses severe computational challenges due to the extended signal duration, which can reach several minutes in current detectors. Neural posterior estimation…

General Relativity and Quantum Cosmology · Physics 2026-04-27 Masaki Iwaya , Vivien Raymond , Soichiro Morisaki , Kazuki Takada

State-space models have been used in many applications, including econometrics, engineering, medical research, etc. The maximum likelihood estimation (MLE) of the static parameter of general state-space models is not straightforward because…

Methodology · Statistics 2025-02-04 Yuxiong Gao , Wentao Li , Rong Chen

Accurately estimating parameters of physiological models is essential to achieving reliable digital twins. For Type 1 Diabetes, this is particularly challenging due to the complexity of glucose-insulin interactions. Traditional methods…

Finite mixtures are a broad class of models useful in scenarios where observed data is generated by multiple distinct processes but without explicit information about the responsible process for each data point. Estimating Bayesian mixture…

Machine Learning · Statistics 2026-03-17 Šimon Kucharský , Paul Christian Bürkner

Spiking Neural Networks (SNNs) offer an energy efficient alternative to conventional Artificial Neural Networks (ANNs) but typically still require a large number of parameters. This work introduces Linearized Bregman Iterations (LBI) as an…

Signal Processing · Electrical Eng. & Systems 2026-03-18 Daniel Windhager , Bernhard A. Moser , Michael Lunglmayr

Amortized Bayesian inference (ABI) offers fast, scalable approximations to posterior densities by training neural surrogates on data simulated from the statistical model. However, ABI methods are highly sensitive to model misspecification:…

Machine Learning · Statistics 2026-01-27 Šimon Kucharský , Aayush Mishra , Daniel Habermann , Stefan T. Radev , Paul-Christian Bürkner

Spiking neural networks (SNNs) provide an energy-efficient solution by utilizing the spike-based and sparse nature of biological systems. Since the advent of Transformers, SNNs have struggled to compete with artificial networks on long…

Neural and Evolutionary Computing · Computer Science 2024-10-24 Yan Zhong , Ruoyu Zhao , Chao Wang , Qinghai Guo , Jianguo Zhang , Zhichao Lu , Luziwei Leng

Traditional methods for spatial inference estimate smooth interpolating fields based on features measured at well-located points. When the spatial locations of some observations are missing, joint inference of the fields and locations is…

Most Probable Explanation (MPE) inference in Probabilistic Graphical Models (PGMs) is a fundamental yet computationally challenging problem arising in domains such as diagnosis, planning, and structured prediction. In many practical…

Artificial Intelligence · Computer Science 2026-02-03 Brij Malhotra , Shivvrat Arya , Tahrima Rahman , Vibhav Giridhar Gogate

Neural simulation-based inference is a powerful class of machine-learning-based methods for statistical inference that naturally handles high-dimensional parameter estimation without the need to bin data into low-dimensional summary…

Data Analysis, Statistics and Probability · Physics 2025-06-16 ATLAS Collaboration

Simulation-based methods for statistical inference have evolved dramatically over the past 50 years, keeping pace with technological advancements. The field is undergoing a new revolution as it embraces the representational capacity of…

Machine Learning · Statistics 2024-10-11 Andrew Zammit-Mangion , Matthew Sainsbury-Dale , Raphaël Huser

Simulation-based inference methods have been shown to be inaccurate in the data-poor regime, when training simulations are limited or expensive. Under these circumstances, the inference network is particularly prone to overfitting, and…

Simulation-based inference enables learning the parameters of a model even when its likelihood cannot be computed in practice. One class of methods uses data simulated with different parameters to infer models of the likelihood-to-evidence…

Machine Learning · Computer Science 2022-06-08 Giulio Isacchini , Natanael Spisak , Armita Nourmohammad , Thierry Mora , Aleksandra M. Walczak

We propose a posterior for Bayesian Likelihood-Free Inference (LFI) based on generalized Bayesian inference. To define the posterior, we use Scoring Rules (SRs), which evaluate probabilistic models given an observation. In LFI, we can…

Methodology · Statistics 2024-09-24 Lorenzo Pacchiardi , Sherman Khoo , Ritabrata Dutta

Bayesian synthetic likelihood (BSL) is a popular method for estimating the parameter posterior distribution for complex statistical models and stochastic processes that possess a computationally intractable likelihood function. Instead of…

Computation · Statistics 2019-07-26 Ziwen An , Leah F South , Christopher Drovandi

Simulation-based inference (SBI) is a method to perform inference on a variety of complex scientific models with challenging inference (inverse) problems. Bayesian Optimal Experimental Design (BOED) aims to efficiently use experimental…

Machine Learning · Statistics 2025-02-13 Vincent D. Zaballa , Elliot E. Hui

We revisit empirical Bayes in the absence of a tractable likelihood function, as is typical in scientific domains relying on computer simulations. We investigate how the empirical Bayesian can make use of neural density estimators first to…

Machine Learning · Statistics 2021-03-02 Maxime Vandegar , Michael Kagan , Antoine Wehenkel , Gilles Louppe