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3D fluorescence microscopy of living organisms has increasingly become an essential and powerful tool in biomedical research and diagnosis. An exploding amount of imaging data has been collected, whereas efficient and effective…

Image and Video Processing · Electrical Eng. & Systems 2019-11-28 Yang Jiao , Mo Weng , Mei Yang

Raman microscopy is a powerful method combining non-invasiveness with no special sample preparation. Because of this remarkable simplicity, it has been widely exploited in many fields, ranging from life and materials sciences, to…

Investigating the cellular internalization pathways of single molecules or single nano-objects is important to understanding cell-matter interactions and to applications in drug delivery and discovery. Imaging and tracking the motion of…

Biological Physics · Physics 2015-06-04 Guosong Hong , Justin Z. Wu , Joshua T. Robinson , Hailiang Wang , Bo Zhang , Hongjie Dai

Electron ptychography has seen a recent surge of interest for phase sensitive imaging at atomic or near-atomic resolution. However, applications are so far mainly limited to radiation-hard samples because the required doses are too high for…

Computational Physics · Physics 2017-02-21 Philipp Michael Pelz , Wen Xuan Qiu , Robert Bücker , Günther Kassier , R. J. Dwayne Miller

Investigation of dynamic processes in cell biology very often relies on the observation in two dimensions of 3D biological processes. Consequently, the data are partial and statistical methods and models are required to recover the…

Applications · Statistics 2020-10-21 Yunjiao Lu , Pierre Hodara , Charles Kervrann , Alain Trubuil

Light detection and ranging (Lidar) single-photon devices capture range and intensity information from a 3D scene. This modality enables long range 3D reconstruction with high range precision and low laser power. A multispectral…

Signal Processing · Electrical Eng. & Systems 2019-09-20 Julián Tachella , Yoann Altmann , Miguel Márquez , Henry Arguello-Fuentes , Jean-Yves Tourneret , Stephen McLaughlin

3D cell tracking in a living organism has a crucial role in live cell image analysis. Cell tracking in C. elegans has two difficulties. First, cell migration in a consecutive frame is large since they move their head during scanning.…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Kaito Shiku , Hiromitsu Shirai , Takeshi Ishihara , Ryoma Bise

Among super-resolution microscopy techniques, structured illumination microscopy (SIM) shows great advances of low phototoxicity, high speed, and excellent performance in long-term dynamic observation, making it especially suitable for live…

Optics · Physics 2025-02-07 Han Wang , Wenshu Wang , Xinzhu Xu , Meiqi Li , Peng Xi

Imaging specimens over large scales and with a sub-micron resolution is instrumental to biomedical research. Yet, the number of pixels to form such an image usually exceeds the number of pixels provided by conventional cameras. While most…

Instrumentation and Detectors · Physics 2019-12-03 Gaelle Recher , Pierre Nassoy , Amaury Badon

The scanning electron microscopy (SEM) is probably one the most fascinating examination approach that has been used since more than two decades to detailed inspection of micro scale objects. Most of the scanning electron microscopes could…

Computer Vision and Pattern Recognition · Computer Science 2016-02-18 Wichai Shanklin

Automated 3D pose estimation of satellites and other known space objects is a critical component of space situational awareness. Ground-based imagery offers a convenient data source for satellite characterization; however, analysis…

Computer Vision and Pattern Recognition · Computer Science 2019-06-27 Maxim Bazik , Brien Flewelling , Manoranjan Majji , Joseph Mundy

Our growing ability to tailor healthcare to the needs of individuals has the potential to transform clinical treatment. However, the measurement of multiple biomarkers to inform clinical decisions requires rapid, effective, and affordable…

Tomographic imaging reveals internal structures of 3D objects and is crucial for medical diagnoses. Visualizing the morphology and appearance of non-planar sparse anatomical structures that extend over multiple 2D slices in tomographic…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Leonhard Rist , Pluvio Stephan , Noah Maul , Linda Vorberg , Hendrik Ditt , Michael Sühling , Andreas Maier , Bernhard Egger , Oliver Taubmann

An exciting recent development for deep-tissue imaging with cellular resolution is three-photon fluorescence microscopy (3PM) with excitation at long wavelengths (1300 and 1700 nm). In the last few years, long-wavelength 3PM has driven…

Medical image retrieval is a valuable field for supporting clinical decision-making, yet current methods primarily support 2D images and require fully annotated queries, limiting clinical flexibility. To address this, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Inye Na , Nejung Rue , Jiwon Chung , Hyunjin Park

We propose a probabilistic shape completion method extended to the continuous geometry of large-scale 3D scenes. Real-world scans of 3D scenes suffer from a considerable amount of missing data cluttered with unsegmented objects. The problem…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Dongsu Zhang , Changwoon Choi , Inbum Park , Young Min Kim

Multiphoton microscopy (MPM) has gained enormous popularity over the years for its capacity to provide high resolution images from deep within scattering samples1. However, MPM is generally based on single-point laser-focus scanning, which…

Optics · Physics 2018-12-14 Devin R. Beaulieu , Ian G. Davison , Thomas G. Bifano , Jerome Mertz

Volumetric biomedical microscopy has the potential to increase the diagnostic information extracted from clinical tissue specimens and improve the diagnostic accuracy of both human pathologists and computational pathology models.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Cheng Jiang , Alexander Gedeon , Yiwei Lyu , Eric Landgraf , Yufeng Zhang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Honglak Lee , Todd Hollon

Capturing biological specimens at large scales with sub-micron resolution is crucial for biomedical research, but conventional cameras often can't handle the pixel requirements. While most microscopes use motorized stages to move samples…

Optics · Physics 2025-03-28 Charlie Kersuzan , Aymerick Bazin , Amaury Badon

Electroluminescence (EL) imaging is a powerful and established technique for assessing the quality of photovoltaic (PV) modules, which consist of many electrically connected solar cells arranged in a grid. The analysis of imperfect…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Evgenii Sovetkin , Ansgar Steland