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3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Hao Zheng , Yizhe Zhang , Lin Yang , Peixian Liang , Zhuo Zhao , Chaoli Wang , Danny Z. Chen

Single-pixel imaging (SPI) is significant for applications constrained by transmission bandwidth or lighting band, where 3D SPI can be further realized through capturing signals carrying depth. Sampling strategy and reconstruction algorithm…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Xinyue Ma , Chenxing Wang

Fast 3D super-resolution imaging is essential for decoding rapidly occurring biological processes. Encoding single molecules to their respective planes enable simultaneous multi-plane super-resolution volume imaging. This saves the…

Biological Physics · Physics 2016-08-04 Partha Pratim Mondal

3D medical image generation is essential for data augmentation and patient privacy, calling for reliable and efficient models suited for clinical practice. However, current methods suffer from limited anatomical fidelity, restricted axial…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Minye Shao , Xingyu Miao , Haoran Duan , Zeyu Wang , Jingkun Chen , Yawen Huang , Xian Wu , Jingjing Deng , Yang Long , Yefeng Zheng

Solving 3D medical inverse problems such as image restoration and reconstruction is crucial in modern medical field. However, the curse of dimensionality in 3D medical data leads mainstream volume-wise methods to suffer from high resource…

Image and Video Processing · Electrical Eng. & Systems 2024-05-27 Jia He , Bonan Li , Ge Yang , Ziwen Liu

Optimizing the performance of organic solar cells (OSCs) hinges on a comprehensive understanding of their nanostructures, yet traditional characterization methods often fall short, delivering incomplete structural snapshots. We introduce…

Numerical investigation of the interaction of electromagnetic fields with eukaryotic cells requires specifically adapted computer models. Virtual microdosimetry, used to investigate exposure, requires volumetric cell models, which are…

We present a cost-effective, simple and fast digital holographic microscopy method based upon Rayleigh-Sommerfeld back propagation for identification of the geometrical shape of a cell. The method was tested using synthetic hologram images…

Optics · Physics 2015-10-28 Johan Zakrisson , Staffan Schedin , Magnus Andersson

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Mapping conformational heterogeneity of macromolecules presents a formidable challenge to X-ray crystallography and cryo-electron microscopy, which often presume its absence. This has severely limited our knowledge of the conformations…

Biological Physics · Physics 2015-05-14 P. Schwander , R. Fung , G. N. Phillips , A. Ourmazd

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

Ascertaining the collective viability of cells in different cell culture conditions has typically relied on averaging colorimetric indicators and is often reported out in simple binary readouts. Recent research has combined viability…

Quantitative Methods · Quantitative Biology 2024-04-03 Kylie J. Trettner , Jeremy Hsieh , Weikun Xiao , Jerry S. H. Lee , Andrea M. Armani

Diffusion models are a special type of generative model, capable of synthesising new data from a learnt distribution. We introduce DISPR, a diffusion-based model for solving the inverse problem of three-dimensional (3D) cell shape…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Dominik J. E. Waibel , Ernst Röell , Bastian Rieck , Raja Giryes , Carsten Marr

We present feature finding and tracking algorithms in 3D in living cells, and demonstrate their utility to measure metrics important in cell biological processes. We developed a computational imaging hybrid approach that combines automated…

Biological Physics · Physics 2015-04-06 Kemp Plumb , Sarah Elaz , Vincent Pelletier , Maria L. Kilfoil

Single particle reconstruction has recently emerged in 3D fluorescence microscopy as a powerful technique to improve the axial resolution and the degree of fluorescent labeling. It is based on the reconstruction of an average volume of a…

Image and Video Processing · Electrical Eng. & Systems 2023-01-24 Thibaut Eloy , Etienne Baudrier , Marine Laporte , Virginie Hamel , Paul Guichard , Denis Fortun

This paper concerns electromagnetic 3D subsurface imaging in connection with sparsity of signal sources. We explored an imaging approach that can be implemented in situations that allow obtaining a large amount of data over a surface or a…

Instrumentation and Methods for Astrophysics · Physics 2016-08-26 Sampsa Pursiainen , Mikko Kaasalainen

Ptychography is an enabling coherent diffraction imaging technique for both fundamental and applied sciences. Its applications in optical microscopy, however, fall short for its low imaging throughput and limited resolution. Here, we report…

We present a method for reconstructing 3D shape of arbitrary Lambertian objects based on measurements by miniature, energy-efficient, low-cost single-photon cameras. These cameras, operating as time resolved image sensors, illuminate the…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Fangzhou Mu , Carter Sifferman , Sacha Jungerman , Yiquan Li , Mark Han , Michael Gleicher , Mohit Gupta , Yin Li

Spectroscopic analysis of large biomolecules is critical in a number of applications, including medical diagnostics and label-free biosensing. Recently, it has been shown that Raman spectroscopy of proteins can be used to diagnose some…

Super-resolution ultrasound imaging has been so far achieved in 3-D by mechanically scanning a volume with a linear probe, by co-aligning multiple linear probes, by using multiplexed 3-D clinical ultrasound systems, or by using 3-D…

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