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The aim of this work is to revisit the phenomenological theory of the interaction between membrane inclusions, mediated by the membrane fluctuations. We consider the case where the inclusions are separated by distances larger than their…

Soft Condensed Matter · Physics 2022-12-28 E. S. Pikina , A. R. Muratov , E. I. Kats , V. V. Lebedev

The flow of ions through permeable channels causes voltage drop in physiological nanodomains such as synapses, dendrites and dendritic spines, and other protrusions. How the voltage changes around channels in these nanodomains has remained…

Soft Condensed Matter · Physics 2025-01-10 Frédéric Paquin-Lefebvre , David Holcman

Understanding how electrolyte-filled porous electrodes respond to an applied potential is important to many electrochemical technologies. Here, we consider a model supercapacitor of two blocking cylindrical pores on either side of a…

Soft Condensed Matter · Physics 2022-04-05 Jie Yang , Mathijs Janssen , Cheng Lian , René van Roij

We formulate a theory of electrostatic interactions in lipid bilayer membranes where both monolayer leaflets contain dissociable moieties that are subject to charge regulation. We specifically investigate the coupling between membrane…

Soft Condensed Matter · Physics 2022-04-01 Petch Khunpetch , Arghya Majee , Rudolf Podgornik

Nonlinear elements in a rectifying circuit can be used to harvest energy from thermal fluctuations either steadily or transitorily. We study an energy harvesting system comprising a small variable capacitor (e.g., free standing graphene)…

Statistical Mechanics · Physics 2026-02-12 L. L. Bonilla , A. Torrente , J. M. Mangum , P. M. Thibado

Diffusion in cell membranes is not just simple two-dimensional Brownian motion, but typically depends on the timescale of the observation. The physical origins of this anomalous sub-diffusion are unresolved, and model systems capable of…

Biological Physics · Physics 2017-10-25 H. L. E. Coker , M. R. Cheetham , D. R. Kattnig , Y. J. Wang , S. Garcia-Manyes , M. I. Wallace

We studied how to charge droplets by induction and how to maximize this charge. In order to aim this objective, we developed an innovative device that avoids non-linear effects and that is able to charge liquids of different nature. The…

Fluid Dynamics · Physics 2013-04-16 Martin Brandenbourger , Stephane Dorbolo

A modified Poisson-Nernst-Planck system in a bounded domain with mixed Dirichlet-Neumann boundary conditions is analyzed. It describes the concentrations of ions immersed in a polar solvent and the correlated electric potential due to the…

Analysis of PDEs · Mathematics 2023-05-25 Ansgar Jüngel , Annamaria Massimini

Plasma membranes appear as deformable systems wherein molecules are free to move and diffuse giving rise to condensed microdomains (composed of ordered lipids, transmembrane proteins and cholesterol) surrounded by disordered lipid…

Soft Condensed Matter · Physics 2024-09-25 Chiara Bernard , Angelo Rosario Carotenuto , Nicola Maria Pugno , Luca Deseri , Massimiliano Fraldi

We review a model for a solid electrolyte derived under thermodynamics principles. We non-dimensionalise and scale the model to identify small parameters, where we identify a scaling that controls the width of the space-charge layer in the…

Applied Physics · Physics 2023-06-23 Laura M. Keane , Iain R. Moyles

We generalize the predictions for attractions between over-all neutral surfaces induced by charge fluctuations/correlations to non-uniform systems that include dielectric discontinuities, as is the case for mixed charged lipid membranes in…

Soft Condensed Matter · Physics 2009-10-31 Rebecca Menes , Philip Pincus , Bean Stein

Signals recorded from neurons with extracellular planar sensors have a wide range of waveforms and amplitudes. This variety is a result of different physical conditions affecting the ion currents through a cellular membrane. The…

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

Electrochemical devices often charge both through Faradaic reactions and electric double layer formation. Here, we study these coupled processes in a model system of a long electrolyte-filled pore subject to a small suddenly-applied…

Statistical Mechanics · Physics 2025-10-27 Timur Aslyamov , Massimiliano Esposito , Mathijs Janssen

Lipid bilayer membranes are the fundamental biological barriers that permit life. The bilayer dynamics largely participates in orchestrating cellular workings and is characterized by substantial stability together with extreme plasticity…

Soft Condensed Matter · Physics 2022-12-05 Matteo Bottacchiari , Mirko Gallo , Marco Bussoletti , Carlo Massimo Casciola

We use a coarse-grained molecular dynamics simulation to investigate the interaction between neutral or charged nanoparticles (NPs) and a vesicle consisting of neutral and negatively charged lipids. We focus on the interaction strengths of…

Soft Condensed Matter · Physics 2019-07-25 Naofumi Shimokawa , Hiroaki Ito , Yuji Higuchi

We present the first application of phase field modeling to electrochemistry. A free energy functional that includes the electrostatic effect of charged particles leads to rich interactions between concentration, electrostatic potential,…

Materials Science · Physics 2007-05-23 J. E. Guyer , W. J. Boettinger , J. A. Warren , G. B. McFadden

We consider a discrete-continuum model of a biomembrane with embedded particles. While the membrane is represented by a continuous surface, embedded particles are described by rigid discrete objects which are free to move and rotate in…

Analysis of PDEs · Mathematics 2021-04-29 Tobias Kies , Carsten Gräser

Using molecular dynamics simulations with recently developed importance sampling methods, we show that the differential capacitance of a model ionic liquid based double-layer capacitor exhibits an anomalous dependence on the applied…

In tissues, cells in direct physical contact with each other can exchange ions or molecules via protein clusters called gap junctions that form channels across the membranes of adjacent cells. Here, we use a simplified biomimetic approach,…