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Factor analysis is a critical component of high dimensional biological data analysis. However, modern biological data contain two key features that irrevocably corrupt existing methods. First, these data, which include longitudinal,…

Methodology · Statistics 2020-09-24 Chris McKennan

In this paper, we analyze a new possible biological surface feature for habitable worlds orbiting other stars: biofluorescence. High ultraviolet (UV) and blue radiation fluxes drive the strongest biofluorescence in terrestrial fluorescent…

Earth and Planetary Astrophysics · Physics 2019-08-13 J. T. O'Malley-James , L. Kaltenegger

Any object on earth has two fundamental properties: it is finite, and it is made of atoms. Structural information about an object can be obtained from diffraction amplitude measurements that account for either one of these traits.…

Optics · Physics 2015-05-13 S. Marchesini

Mass spectrometry is the dominant technology in the field of proteomics, enabling high-throughput analysis of the protein content of complex biological samples. Due to the complexity of the instrumentation and resulting data, sophisticated…

The Pierre Auger Observatory concluded its first phase of data taking after seventeen years of operation. The dataset collected by its surface and fluorescence detectors (FD and SD) provides us with the most precise estimates of the energy…

High Energy Astrophysical Phenomena · Physics 2025-01-06 Vladimír Novotný

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

Biological Physics · Physics 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

Fluorescence microscopy is widely used in biological imaging, however scattering from tissues strongly limits its applicability to a shallow depth. In this work we adapt a methodology inspired from stellar speckle interferometry, and…

Luminescence imaging is invaluable for studying biological and material systems, particularly when advanced protocols that exploit temporal dynamics are employed. However, implementing such protocols often requires custom instrumentation,…

Instrumentation and Detectors · Physics 2025-09-16 Ian Coghill , Alienor Lahlou , Andrea Lodetti , Shizue Matsubara , Johann Boucle , Thomas Le Saux , Ludovic Jullien

Optical interference is not only a fundamental phenomenon that has enabled new theories of light to be derived but it has also been used in interferometry for the measurement of small displacements, refractive index changes and surface…

Optics · Physics 2021-10-28 Chen Yang , Zhi-Yuan Zhou , Yan Li , Shi-Kai Liu , Zheng Ge , Guang-Can Guo , Bao-Sen Shi

Ongoing fascination with quantum mechanics keeps driving the development of the wide field of quantum-optics, including its neutron-optics branch. Application of neutron-optical methods and, especially, neutron interferometry and…

Quantum Physics · Physics 2016-06-21 J. Klepp , S. Sponar , Y. Hasegawa

A critical review of frequency-shift phenomena a la Doppler effect is presented. The importance of Fermi's theory of 1932 is pointed out, and it is argued that there exists a gap in our understanding of this phenomena at a fundamental…

Quantum Physics · Physics 2007-05-23 S C Tiwari

Tendencies in five main branches of atomic spectrometry (absorption, emission, mass, fluorescence and ionization spectrometry) are considered. The first three techniques are the most widespread and universal, with the best sensitivity…

Instrumentation and Detectors · Physics 2007-05-23 A. A. Bol'shakov , A. A. Ganeev , V. M. Nemets

We discuss the spontaneous emission from a coherently prepared and microwave driven doublet of potentially closely spaced excited states to a common ground level. Multiple interference mechanisms are identified which may lead to…

Quantum Physics · Physics 2009-10-31 E. Paspalakis , C. H. Keitel , P. L. Knight

Surface plasmons are usually described as surface waves with either a complex wavevector or a complex frequency. When discussing their merits in terms of field confinment or enhancement of the local density of states, controversies…

The phase space structure of certain quantum states reveals structure on a scale that is small compared to the Planck area. Using an analog between the wavefunction of a single photon and the electric field of a classical ultrashort optical…

Optics · Physics 2015-05-14 Dane R. Austin , Tobias Witting , Ian A. Walmsley

Turing patterns play a fundamental role in morphogenesis and population dynamics, encoding key information about the underlying biological mechanisms. Yet, traditional inverse problems have largely relied on non-biological data such as…

Analysis of PDEs · Mathematics 2025-09-10 Yuhan Li , Hongyu Liu , Catharine W. K. Lo

Resonance fluorescence of a two-level emitter displays persistently anti-bunching irrespective of the excitation intensity, but inherits the driving laser's linewidth under weak monochromatic excitation. These properties are commonly…

Fourier phasing is the problem of retrieving Fourier phase information from Fourier intensity data. The standard Fourier phase retrieval (without a mask) is known to have many solutions which cause the standard phasing algorithms to…

Optics · Physics 2015-06-12 Albert Fannjiang , Wenjing Liao

This paper develops the theory behind the bispectrum, a concept that is well established in statistical signal processing but not, until recently, extended to computer vision as a source of frequency-domain invariants. Recent papers on…

Group Theory · Mathematics 2012-02-15 Ramakrishna Kakarala

Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

Optics · Physics 2022-01-26 Yi Xue , David Ren , Laura Waller