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Diabetic retinopathy (DR) is a leading cause of blindness worldwide, and AI systems can expand access to fundus photography screening. Current FDA-cleared systems primarily provide binary referral outputs, where this minimal output may…

Artificial Intelligence · Computer Science 2025-09-17 Nadim Barakat , William Lotter

In this paper, models of the blood glucose (BG) dynamics in people with Type 1 diabetes (T1D) in response to moderate intensity aerobic activity are derived from physiology-based first principles and system identification experiments. We…

Systems and Control · Electrical Eng. & Systems 2023-07-18 Mehrad Jaloli , Marzia Cescon

Accurate long-horizon glucose forecasting is critical for automated insulin delivery systems, which help people with type 1 diabetes (T1D) manage their glucose and avoid dangerous hypoglycemia. However, standard recursive long short-term…

Machine Learning · Computer Science 2026-05-19 Phat Tran , Neville Mehta , Clara Mosquera-Lopez , Robert H. Dodier , Lizhong Chen , Peter G. Jacobs

Diabetes mellitus is a chronic metabolic disorder that has emerged as one of the major health problems worldwide due to its high prevalence and serious complications, which are pricey to manage. Effective management requires good glycemic…

Machine Learning · Computer Science 2024-07-01 Abolfazl Zarghani

The insulin sensitivity (IS) of the human body changes with a circadian rhythm. This adds to the time-varying feature of the glucose metabolism process and places challenges on the blood glucose (BG) control of patients with Type 1 Diabetes…

Systems and Control · Computer Science 2021-01-29 Lukas Ortmann , Dawei Shi , Eyal Dassau , Francis J. Doyle , Steffen Leonhardt , Berno J. E. Misgeld

The global prevalence of diabetes, particularly type 2 diabetes mellitus (T2DM), is rapidly increasing, posing significant health and economic challenges. T2DM not only disrupts blood glucose regulation but also damages vital organs such as…

Machine Learning · Computer Science 2025-06-09 Praveen Kumar , Vincent T. Metzger , Scott A. Malec

As continuous glucose monitors (CGMs) are used increasingly by diabetic patients, new and intuitive tools are needed to help patients and their physicians use these streams of data to improve blood glucose management. In this paper, we…

Quantitative Methods · Quantitative Biology 2013-05-15 Edward Aboufadel

Standard objective functions used during the training of neural-network-based predictive models do not consider clinical criteria, leading to models that are not necessarily clinically acceptable. In this study, we look at this problem from…

Quantitative Methods · Quantitative Biology 2020-09-24 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

The growing worldwide incidence of diabetes requires more effective approaches for managing blood glucose levels. Insulin delivery systems have advanced significantly, with artificial intelligence (AI) playing a key role in improving their…

Artificial Intelligence · Computer Science 2025-03-25 Maria Panagiotou , Knut Stroemmen , Lorenzo Brigato , Bastiaan E. de Galan , Stavroula Mougiakakou

The conventional method of glucose measurement such as pricking blood from the body is prevalent which brings pain and trauma. Invasive methods of measurement sometimes raise the risk of blood infection to the patient. Sometimes, some of…

Medical Physics · Physics 2023-08-24 Prateek Jain , Amit Joshi , Saraju Mohanty

Graph deep learning (GDL) has demonstrated impressive performance in predicting population-based brain disorders (BDs) through the integration of both imaging and non-imaging data. However, the effectiveness of GDL based methods heavily…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Luhui Cai , Weiming Zeng , Hongyu Chen , Hua Zhang , Yueyang Li , Yu Feng , Hongjie Yan , Lingbin Bian , Wai Ting Siok , Nizhuan Wang

Modeling the dynamics of probability distributions from time-dependent data samples is a fundamental problem in many fields, including digital health. The goal is to analyze how the distribution of a biomarker, such as glucose, changes over…

Machine Learning · Statistics 2025-09-18 Antonio Álvarez-López , Marcos Matabuena

Blood glucose value prediction is an important task in diabetes management. While it is reported that glucose concentration is sensitive to social context such as mood, physical activity, stress, diet, alongside the influence of diabetes…

Machine Learning · Statistics 2019-09-05 Mohammad Akbari , Rumi Chunara

Diabetes mellitus is a common disease of human body caused by a group of metabolic disorders where the sugar levels over a prolonged period is very high. It affects different organs of the human body which thus harm a large number of the…

Machine Learning · Computer Science 2019-02-27 Md. Faisal Faruque , Asaduzzaman , Iqbal H. Sarker

The prevalence of Diabetes mellitus (DM) in the Middle East is exceptionally high as compared to the rest of the world. In fact, the prevalence of diabetes in the Middle East is 17-20%, which is well above the global average of 8-9%.…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Muhammad Usman , Kashif Ahmad , Amir Sohail , Marwa Qaraqe

High-dimensional neuroimaging data presents challenges for assessing neurodegenerative diseases due to complex non-linear relationships. Variational Autoencoders (VAEs) can encode scans into lower-dimensional latent spaces capturing…

Insulin resistance (IR) is a key precursor to diabetes and a significant risk factor for cardiovascular disease. Traditional IR assessment methods require multiple blood tests. We developed a simple AI model using only fasting blood glucose…

Machine Learning · Computer Science 2025-03-10 Weihao Gao , Zhuo Deng , Zheng Gong , Ziyi Jiang , Lan Ma

Objective: The design of an Artificial Pancreas (AP) to regulate blood glucose levels requires reliable control methods. Model Predictive Control has emerged as a promising approach for glycemia control. However, model--based control…

Optimization and Control · Mathematics 2022-02-02 Claudia Lopez-Zazueta , Øyvind Stavdahl , Anders Lyngvi Fougner

Rapid changes in blood glucose levels can have severe and immediate health consequences, leading to the need to develop indices for assessing these rapid changes based on continuous glucose monitoring (CGM) data. We proposed a CGM index,…

Quantitative Methods · Quantitative Biology 2025-06-17 Dandan Wang , Xiaoyan Chen , Jingxiang Lin , Teng Zhang , Lianyi Huang , Dongliang Leng , Xiaohua Douglas Zhang , Gang Li

Background and objective: Diabetes is one of the four leading causes of death worldwide, necessitating daily blood glucose monitoring. While sweat offers a promising non-invasive alternative for glucose monitoring, its application remains…

Quantitative Methods · Quantitative Biology 2024-12-05 Xiaoyu Yin , Elisabetta Peri , Eduard Pelssers , Jaap den Toonder , Lisa Klous , Hein Daanen , Massimo Mischi