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Accurate nuclei segmentation in microscopy whole slide images (WSIs) remains challenging due to variability in staining, imaging conditions, and tissue morphology. We propose CellGenNet, a knowledge distillation framework for robust…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Srijan Ray , Bikesh K. Nirala , Jason T. Yustein , Sundaresh Ram

Infrared and visible dual-modality tasks such as semantic segmentation and object detection can achieve robust performance even in extreme scenes by fusing complementary information. Most current methods design task-specific frameworks,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Fangcen Liu , Chenqiang Gao , Fang Chen , Pengcheng Li , Junjie Guo , Deyu Meng

Inspired by recent advances of deep learning in instance segmentation and object tracking, we introduce video object segmentation problem as a concept of guided instance segmentation. Our model proceeds on a per-frame basis, guided by the…

Computer Vision and Pattern Recognition · Computer Science 2019-02-05 Anna Khoreva , Federico Perazzi , Rodrigo Benenson , Bernt Schiele , Alexander Sorkine-Hornung

A major obstacle in instance segmentation is that existing methods often need many per-pixel labels in order to be effective. These labels require large human effort and for certain applications, such labels are not readily available. To…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Issam H. Laradji , David Vazquez , Mark Schmidt

Weakly-supervised methods typically guided the pixel-wise training by comparing the predictions to single-level labels containing diverse segmentation-related information at once, but struggled to represent delicate feature differences…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Jianning Chi , Zelan Li , Huixuan Wu , Wenjun Zhang , Ying Huang

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

Nucleus instance segmentation from histopathology images suffers from the extremely laborious and expert-dependent annotation of nucleus instances. As a promising solution to this task, annotation-efficient deep learning paradigms have…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Yu Ming , Zihao Wu , Jie Yang , Danyi Li , Yuan Gao , Changxin Gao , Gui-Song Xia , Yuanqing Li , Li Liang , Jin-Gang Yu

Nuclei segmentation and classification is the first and most crucial step that is utilized for many different microscopy medical analysis applications. However, it suffers from many issues such as the segmentation of small objects,…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Hussam Azzuni , Muhammad Ridzuan , Min Xu , Mohammad Yaqub

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

Prototype learning is extensively used for few-shot segmentation. Typically, a single prototype is obtained from the support feature by averaging the global object information. However, using one prototype to represent all the information…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Gen Li , Varun Jampani , Laura Sevilla-Lara , Deqing Sun , Jonghyun Kim , Joongkyu Kim

State-of-the-art semantic segmentation methods require sufficient labeled data to achieve good results and hardly work on unseen classes without fine-tuning. Few-shot segmentation is thus proposed to tackle this problem by learning a model…

Computer Vision and Pattern Recognition · Computer Science 2020-08-05 Zhuotao Tian , Hengshuang Zhao , Michelle Shu , Zhicheng Yang , Ruiyu Li , Jiaya Jia

This paper presents a novel approach for learning instance segmentation with image-level class labels as supervision. Our approach generates pseudo instance segmentation labels of training images, which are used to train a fully supervised…

Computer Vision and Pattern Recognition · Computer Science 2019-05-13 Jiwoon Ahn , Sunghyun Cho , Suha Kwak

Accurate segmenting nuclei instances is a crucial step in computer-aided image analysis to extract rich features for cellular estimation and following diagnosis as well as treatment. While it still remains challenging because the wide…

Computer Vision and Pattern Recognition · Computer Science 2019-03-14 Yanning Zhou , Omer Fahri Onder , Qi Dou , Efstratios Tsougenis , Hao Chen , Pheng-Ann Heng

Instance segmentation in videos, which aims to segment and track multiple objects in video frames, has garnered a flurry of research attention in recent years. In this paper, we present a novel weakly supervised framework with…

Computer Vision and Pattern Recognition · Computer Science 2022-12-16 Liqi Yan , Qifan Wang , Siqi Ma , Jingang Wang , Changbin Yu

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

We present FourierNet, a single shot, anchor-free, fully convolutional instance segmentation method that predicts a shape vector. Consequently, this shape vector is converted into the masks' contour points using a fast numerical transform.…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Hamd ul Moqeet Riaz , Nuri Benbarka , Andreas Zell

Training a computer vision system to segment a novel class typically requires collecting and painstakingly annotating lots of images with objects from that class. Few-shot segmentation techniques reduce the required number of images to…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Shreyas Chandgothia , Ardhendu Sekhar , Amit Sethi

Instance segmentation of biological images is essential for studying object behaviors and properties. The challenges, such as clustering, occlusion, and adhesion problems of the objects, make instance segmentation a non-trivial task.…

Computer Vision and Pattern Recognition · Computer Science 2019-11-22 Jingru Yi , Hui Tang , Pengxiang Wu , Bo Liu , Daniel J. Hoeppner , Dimitris N. Metaxas , Lianyi Han , Wei Fan

In pathology, accurate and efficient analysis of Hematoxylin and Eosin (H\&E) slides is crucial for timely and effective cancer diagnosis. Although many deep learning solutions for nuclei instance segmentation and classification exist in…

Image and Video Processing · Electrical Eng. & Systems 2024-08-12 Cristian Tommasino , Cristiano Russo , Antonio Maria Rinaldi

Instance segmentation is of great importance for many biological applications, such as study of neural cell interactions, plant phenotyping, and quantitatively measuring how cells react to drug treatment. In this paper, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Jingru Yi , Pengxiang Wu , Hui Tang , Bo Liu , Qiaoying Huang , Hui Qu , Lianyi Han , Wei Fan , Daniel J. Hoeppner , Dimitris N. Metaxas